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Protein Overview: gi|17864836, gi|...

General Information:
Name(s) found: gi|17864836 [NCBI NR]
gi|149049610 [NCBI NR]
Description(s) found:
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  • gi|17864836|gb|AAL47071.1|AF394938_1 L-type calcium channel alpha-1c subunit [Rattus norvegicus] [NCBI NR]
  • gi|149049610|gb|EDM02064.1| calcium channel, voltage-dependent, L type, alpha 1C subunit, isoform CRA_c [Rattus norvegicus] [NCBI NR]
  • L-type calcium channel alpha-1c subunit [Rattus norvegicus] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 L-type calcium channel alpha-1c subunit [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • calcium channel, voltage-dependent, L type, alpha 1C subunit, isoform CRA_c [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 L-TYPE CALCIUM CHANNEL ALPHA-1C SUBUNIT [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Cacna1c Calcium channel, voltage-dependent, L type, alpha 1C subunit, isoform CRA_c [rat-ipi-250309-contam.fasta]
  • Calcium channel, voltage-dependent, L type, alpha 1C subunit, isoform CRA_c OS=Rattus norvegicus GN=Cacna1c [011711_HMR.fasta]
  • Calcium channel, voltage-dependent, L type, alpha 1C subunit, isoform CRA_c OS=Rattus norvegicus GN=Cacna1c PE=2 SV=1 [20141208_RAT.fasta]
    • Organism: Rattus norvegicus
    Length: 2170 amino acids

    Gene Ontology:
    Cellular Component: presynaptic membrane [IDA]
    postsynaptic density [UNKNOWN][IDA]
    caveolar macromolecular signaling complex [UNKNOWN][IEA]
    voltage-gated calcium channel complex [UNKNOWN][IDA][IEA][TAS]
    neuronal cell body [UNKNOWN][IDA]
    plasma membrane [UNKNOWN]
    membrane fraction [UNKNOWN][IDA]
    nucleus [IDA]
    Z disc [IDA]
    T-tubule [IDA]
    dendrite [IDA]
    cytoplasm [UNKNOWN][IEA]
    sarcolemma [IDA]
    dendritic shaft [UNKNOWN][IEA]
    membrane [IEA]
    integral to membrane [UNKNOWN][IEA]
    Biological Process: transmembrane transport [IEA]
    insulin secretion [UNKNOWN][IEA]
    synaptic transmission [UNKNOWN][IEA]
    visual learning [UNKNOWN][IEA]
    regulation of organ growth [UNKNOWN][IEA]
    regulation of blood pressure [UNKNOWN][IEA]
    cellular calcium ion homeostasis [UNKNOWN][IEA]
    elevation of cytosolic calcium ion concentration [UNKNOWN]
    adult walking behavior [UNKNOWN][IEA]
    ion transport [IEA]
    smooth muscle contraction [UNKNOWN][IEA]
    calcium ion transport [UNKNOWN][IEA][IMP]
    glucose homeostasis [UNKNOWN][IEA]
    growth hormone secretion [UNKNOWN][IEA]
    calcium ion-dependent exocytosis [UNKNOWN][IEA]
    smooth muscle contraction involved in micturition [UNKNOWN][IEA]
    regulation of vasoconstriction [UNKNOWN][IEA]
    Molecular Function: ion channel activity [IEA]
    calmodulin binding [UNKNOWN][IEA]
    protein domain specific binding [IPI]
    protein binding [UNKNOWN][IPI]
    voltage-gated ion channel activity [IEA]
    dihydropyridine-sensitive calcium channel activity [UNKNOWN][IEA]
    voltage-gated calcium channel activity [UNKNOWN][IDA][IEA][IMP][TAS]
    protein phosphatase 2A binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRAFAQPST PPYQPLSSCL SEDTERKFKG KVVHEAQLNC FYISPGGSNY GSPRPAHANM  60
   61 NANAAAGLAP EHIPTPGAAL SWQAAIDAAR QAKLMGSAGN ATISTVSSTQ RKRQQYGKPK 120
  121 KQGGTTATRP PRALLCLTLK NPIRRACISI VEWKPFEIII LLTIFANCVA LAIYIPFPED 180
  181 DSNATNSNLE RVEYLFLIIF TVEAFLKVIA YGLLFHPNAY LRNGWNLLDF IIVVVGLFSA 240
  241 ILEQATKADG ANALGGKGAG FDVKALRAFR VLRPLRLVSG VPSLQVVLNS IIKAMVPLLH 300
  301 IALLVLFVII IYAIIGLELF MGKMHKTCYN QEGIIDVPAE EDPSPCALET GHGRQCQNGT 360
  361 VCKPGWDGPK HGITNFDNFA FAMLTVFQCI TMEGWTDVLY WMQDAMGYEL PWVYFVSLVI 420
  421 FGSFFVLNLV LGVLSGEFSK EREKAKARGD FQKLREKQQL EEDLKGYLDW ITQAEDIDPE 480
  481 NEDEGMDEDK PRNMSMPTSE TESVNTENVA GGDIEGENCG ARLAHRISKS KFSRYWRRWN 540
  541 RFCRRKCRAA VKSNVFYWLV IFLVFLNTLT IASEHYNQPH WLTEVQDTAN KALLALFTAE 600
  601 MLLKMYSLGL QAYFVSLFNR FDCFIVCGGI LETILVETKI MSPLGISVLR CVRLLRIFKI 660
  661 TRYWNSLSNL VASLLNSVRS IASLLLLLFL FIIIFSLLGM QLFGGKFNFD EMQTRRSTFD 720
  721 NFPQSLLTVF QILTGEDWNS VMYDGIMAYG GPSFPGMLVC IYFIILFICG NYILLNVFLA 780
  781 IAVDNLADAE SLTSAQKEEE EEKERKKLAR TASPEKKQEV MEKPAVEESK EEKIELKSIT 840
  841 ADGESPPTTK INMDDLQPSE NEDKSPHSNP DTAGEEDEEE PEMPVGPRPR PLSELHLKEK 900
  901 AVPMPEASAF FIFSPNNRFR LQCHRIVNDT IFTNLILFFI LLSSISLAAE DPVQHTSFRN 960
  961 HILGNADYVF TSIFTLEIIL KMTAYGAFLH KGSFCRNYFN ILDLLVVSVS LISFGIQSSA1020
 1021 INVVKILRVL RVLRPLRAIN RAKGLKHVVQ CVFVAIRTIG NIVIVTTLLQ FMFACIGVQL1080
 1081 FKGKLYTCSD SSKQTEAECK GNYITYKDGE VDHPIIQPRS WENSKFDFDN VLAAMMALFT1140
 1141 VSTFEGWPEL LYRSIDSHTE DKGPIYNYRV EISIFFIIYI IIIAFFMMNI FVGFVIVTFQ1200
 1201 EQGEQEYKNC ELDKNQRQCV EYALKARPLR RYIPKNQHQY KVWYVVNSTY FEYLMFVLIL1260
 1261 LNTICLAMQH YGQSCLFKIA MNILNMLFTG LFTVEMILKL IAFKPKHYFC DAWNTFDALI1320
 1321 VVGSIVDIAI TEVHPAEHTQ CSPSMSAEEN SRISITFFRL FRVMRLVKLL SRGEGIRTLL1380
 1381 WTFIKSFQAL PYVALLIVML FFIYAVIGMQ VFGKIALNDT TEINRNNNFQ TFPQAVLLLF1440
 1441 RCATGEAWQD IMLACMPGKK CAPESEPSNS TEGETPCGSS FAVFYFISFY MLCAFLIINL1500
 1501 FVAVIMDNFD YLTRDWSILG PHHLDEFKRI WAEYDPEAKG RIKHLDVVTL LRRIQPPLGF1560
 1561 GKLCPHRVAC KRLVSMNMPL NSDGTVMFNA TLFALVRTAL RIKTEGNLEQ ANEELRAIIK1620
 1621 KIWKRTSMKL LDQVVPPAGD DEVTVGKFYA TFLIQEYFRK FKKRKEQGLV GKPSQRNALS1680
 1681 LQAGLRTLHD IGPEIRRAIS GDLTAEEELD KAMKEAVSAA SEDDIFRRAG GLFGNHVSYY1740
 1741 QSDSRSNFPQ TFATQRPLHI NKTGNNQADT ESPSHEKLVD STFTPSSYSS TGSNANINNA1800
 1801 NNTALGRFPH PAGYSSTVST VEGHGPPLSP AVRVQEAAWK LSSKRCHSRE SQGATVSQDM1860
 1861 FPDETRSSVR LSEEVEYCSE PSLLSTDILS YQDDENRQLT CLEEDKREIQ PSPKRSFLRS1920
 1921 ASLGRRASFH LECLKRQKDQ GGDISQKTAL PLHLVHHQAL AVAGLSPLLQ RSHSPSTFPR1980
 1981 PRPTPPVTPG SRGRPLQPIP TLRLEGAESS EKLNSSFPSI HCSSWSEETT ACSGGSSMAR2040
 2041 RARPVSLTVP SQAGAPGRQF HGSASSLVEA VLISEGLGQF AQDPKFIEVT TQELADACDM2100
 2101 TIEEMENAAD NILSGGAQQS PNGTLLPFVN CRDPGQDRAV VPEDESCVYA LGRGRSEEAL2160
 2161 PDSRSYVSNL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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