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Protein Overview: gi|494469, gi|19...

General Information:
Name(s) found: gi|494469 [NCBI NR]
gi|23200120 [NCBI NR]
gi|23200119 [NCBI NR]
gi|197305016 [NCBI NR]
Description(s) found:
Found 9 descriptions.
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  • gi|494469|pdb|1PPG|E Chain E, The Refined 2.3 Angstroms Crystal Structure Of Human Leukocyte Elastase In A Complex With A Valine Chloromethyl Ketone Inhibitor [NCBI NR]
  • gi|23200120|pdb|1H1B|B Chain B, Crystal Structure Of Human Neutrophil Elastase Complexed With An Inhibitor (Gw475151) [NCBI NR]
  • gi|23200119|pdb|1H1B|A Chain A, Crystal Structure Of Human Neutrophil Elastase Complexed With An Inhibitor (Gw475151) [NCBI NR]
  • gi|197305016|pdb|2Z7F|E Chain E, Crystal Structure Of The Complex Of Human Neutrophil Elastase With 12SLPI [NCBI NR]
    • Organism: Homo sapiens
    Length: 218 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVGGRRARPH AWPFMVSLQL RGGHFCGATL IAPNFVMSAA HCVANVNVRA VRVVLGAHNL  60
   61 SRREPTRQVF AVQRIFENGY DPVNLLNDIV ILQLNGSATI NANVQVAQLP AQGRRLGNGV 120
  121 QCLAMGWGLL GRNRGIASVL QELNVTVVTS LCRRSNVCTL VRGRQAGVCF GDSGSPLVCN 180
  181 GLIHGIASFV RGGCASGLYP DAFAPVAQFV NWIDSIIQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. gi|112491310 gi|494469, gi|19...

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..218] PSI-BLAST 48.154902 Elastase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  5.91209560688646 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  5.52773635813967 bayes_pls_golite062009
  • serine hydrolase activity
    		•  5.5105092190926 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  5.49703869306079 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  5.39623690248556 bayes_pls_golite062009
  • endopeptidase activity
    		•  5.32070018460528 bayes_pls_golite062009
  • hydrolase activity
    		•  4.40346950809697 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  2.01328116441763 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.73928761064649 bayes_pls_golite062009
  • DNA binding
    		•  1.61536775064425 bayes_pls_golite062009
  • heparin binding
    		•  1.48285358055737 bayes_pls_golite062009
  • thrombospondin receptor activity
    		•  1.44312413043539 bayes_pls_golite062009
  • catalytic activity
    		•  1.40927913545237 bayes_pls_golite062009
  • polysaccharide binding
    		•  1.34665327732001 bayes_pls_golite062009
  • binding
    		•  1.30738106455622 bayes_pls_golite062009
  • protein binding
    		•  1.30414885212044 bayes_pls_golite062009
  • fucose binding
    		•  1.28001086938735 bayes_pls_golite062009
  • receptor activity
    		•  1.10676631226741 bayes_pls_golite062009
  • calcium-dependent protein binding
    		•  1.10244132298625 bayes_pls_golite062009
  • serine-type aminopeptidase activity
    		•  0.964413112640311 bayes_pls_golite062009
  • signal transducer activity
    		•  0.885246794092463 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.885246794092463 bayes_pls_golite062009
  • growth factor activity
    		•  0.848900101748605 bayes_pls_golite062009
  • receptor binding
    		•  0.79054390509229 bayes_pls_golite062009
  • sodium channel regulator activity
    		•  0.30724450617383 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.39

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle