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View Structure Prediction Details

Protein: gi|494469, gi|19...
Organism: Homo sapiens
Length: 218 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|494469, gi|19....

Description E-value Query
Range
Subject
Range
gi|47225569 - gi|47225569|emb|CAG12052.1| unnamed protein product [Tetraodon nigroviridis]
228.0 [0..1] [217..493]
gi|87130885 - gi|87130885|gb|ABD24064.1| intein-trypsinogen fusion protein [synthetic construct]
227.0 [0..1] [217..164]
TMPS6_MOUSE - Transmembrane protease, serine 6 - Mus musculus (Mouse)
227.0 [0..1] [217..565]
gi|114683675 - gi|114683675|ref|XP_514836.2| PREDICTED: enterokinase [Pan troglodytes]
227.0 [0..1] [218..785]
gi|76608355 - gi|76608355|ref|XP_618102.2| PREDICTED: similar to Transmembrane protease, serine 3 [Bos taurus]
226.0 [0..1] [218..251]
TMPRSS15 - transmembrane protease, serine 15
226.0 [0..1] [218..785]
gi|74001330 - gi|74001330|ref|XP_544824.2| PREDICTED: similar to Enteropeptidase precursor (Enterokinase) [Canis f...
226.0 [0..1] [218..800]
gi|50729868 - gi|50729868|ref|XP_425539.1| PREDICTED: similar to enteropeptidase precursor [Gallus gallus]
226.0 [0..1] [217..805]

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Predicted Domain #1
Region A:
Residues: [1-218]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVGGRRARPH AWPFMVSLQL RGGHFCGATL IAPNFVMSAA HCVANVNVRA VRVVLGAHNL  60
   61 SRREPTRQVF AVQRIFENGY DPVNLLNDIV ILQLNGSATI NANVQVAQLP AQGRRLGNGV 120
  121 QCLAMGWGLL GRNRGIASVL QELNVTVVTS LCRRSNVCTL VRGRQAGVCF GDSGSPLVCN 180
  181 GLIHGIASFV RGGCASGLYP DAFAPVAQFV NWIDSIIQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.154902
Match: 1h1bA
Description: Elastase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 5.91209560688646 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 5.52773635813967 bayes_pls_golite062009
serine hydrolase activity 5.5105092190926 bayes_pls_golite062009
serine-type peptidase activity 5.49703869306079 bayes_pls_golite062009
serine-type endopeptidase activity 5.39623690248556 bayes_pls_golite062009
endopeptidase activity 5.32070018460528 bayes_pls_golite062009
hydrolase activity 4.40346950809697 bayes_pls_golite062009
glycosaminoglycan binding 2.01328116441763 bayes_pls_golite062009
nucleic acid binding 1.73928761064649 bayes_pls_golite062009
DNA binding 1.61536775064425 bayes_pls_golite062009
heparin binding 1.48285358055737 bayes_pls_golite062009
thrombospondin receptor activity 1.44312413043539 bayes_pls_golite062009
catalytic activity 1.40927913545237 bayes_pls_golite062009
polysaccharide binding 1.34665327732001 bayes_pls_golite062009
binding 1.30738106455622 bayes_pls_golite062009
protein binding 1.30414885212044 bayes_pls_golite062009
fucose binding 1.28001086938735 bayes_pls_golite062009
receptor activity 1.10676631226741 bayes_pls_golite062009
calcium-dependent protein binding 1.10244132298625 bayes_pls_golite062009
serine-type aminopeptidase activity 0.964413112640311 bayes_pls_golite062009
signal transducer activity 0.885246794092463 bayes_pls_golite062009
molecular transducer activity 0.885246794092463 bayes_pls_golite062009
growth factor activity 0.848900101748605 bayes_pls_golite062009
receptor binding 0.79054390509229 bayes_pls_golite062009
sodium channel regulator activity 0.30724450617383 bayes_pls_golite062009

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