Protein Overview: gi|42562972

General Information:
Name(s) found:	gi\|42562972 [NCBI NR]
Description(s) found: SHOW ONLY BEST	gi\|42562972\|ref\|NP_176723.3\| GTB1; RNA binding / hydrolase, acting on ester bonds / transcription elongation regulator [Arabidopsis thaliana] [NCBI NR] glycine-rich protein [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas] \| Symbols: GTB1 \| GTB1 (GLOBAL TRANSCRIPTION FACTOR GROUP B1); RNA binding / hydrolase, acting on ester bonds / transcription elongation regulator \| chr1:24310608-24317990 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta] GTB1; RNA binding / hydrolase, acting on ester bonds [Arabidopsis thaliana] [nr-271106-contam.fasta] \| Symbols: GTB1 \| global transcription factor group B1 \| chr1:24306945-24314327 REVERSE LENGTH=1647 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta] Transcription elongation factor SPT6 OS=Arabidopsis thaliana GN=GTB1 PE=4 SV=1 [ARATH-contam.fasta] Transcription elongation factor SPT6-like protein OS=Arabidopsis thaliana GN=GTB1 PE=4 SV=1 [ARATH.fasta.20160308]
Organism:	Arabidopsis thaliana
Length:	1647 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	chromatin assembly or disassembly [ISS] transcription initiation [ISS]
Molecular Function:	hydrolase activity, acting on ester bonds [IEA] transcription elongation regulator activity [IEA] RNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARNAISDDE EDHELEDDDG EPVHGDPAEH DENDDEEDDD DVGNEYENDG FIVNDEDEEE  60
   61 EEEEDEERKD SDEERQKKKK KRKKKDEGLD EDDYLLLQDN NVKFKKRQYK RLKKAQREQG 120
  121 NGQGESSDDE FDSRGGTRRS AEDKIKDRLF DDVDVDDPPD DVGDEEDLVV EEDVVGSEDE 180
  181 MADFIVDEDD EHGPPKRGNS KKKKYRQGSD ITAMRDANEI FGDVDELLTI RKKGLASNQR 240
  241 MERRLEDEFE PTVLSEKYMT GNDDEIRQLD IPERMQISEE STGSPPVDEI SIEEESNWIY 300
  301 AQLASQLRES DGTFDGRGFS VNKDDIAKFL ELHHVQKLEI PFIAMYRKEQ CRSLLDTGDF 360
  361 DGANQGKKPE TKWHKVFWMI HDLDKKWLLL RKRKMALHGY YTKRYEEESR RVYDETRLNL 420
  421 NQYLFESVIK SLKVAETERE VDDVDSKFNL HFPPGEIGVD EGQYKRPKRK SQYSICSKAG 480
  481 LWEVANKFGY SAEQLGLALS LEKLVDELED AKETPEEMAK NFVCAMFENS LAVLKGARHM 540
  541 AAVEISCEPS VKKYVRGIYM ENAVVSTSPT ADGNTVIDSF HQFSGIKWLR EKPLSKFEGA 600
  601 QWLLIQKGEE EKLLQVTFKL PENYMNRLIS DCNEHYLSVG VSKYAQLWNE QRKLILEDAL 660
  661 HAFLLPSMEK EARSLLTSRA KSRLLSEYGQ ALWNKVSAGP YQKKEMDINL DEEAAPRVMA 720
  721 CCWGPGKPPN TFVMLDSSGE VLDVLYAGSL TSRSQNVNDQ QRKKSDQDRV LKFMMDHQPH 780
  781 VVALGAVNLS CTRLKDDIYE VIFQMVEEKP RDVGHGMDDL SIVYVDESLP RLYENSRISG 840
  841 EQLPQQSGNV RRAVALGRYL QNPLAMVATL CGPGREILSW KLHPLENFLQ LDEKYGMVEQ 900
  901 VMVDITNQVG IDINLAASHD WFFSPLQFIS GLGPRKAASL QRSLVRAGSI FVRKDLIMHG 960
  961 LGKKVFVNAA GFLRIRRSGL AASSSQFIDL LDDTRIHPES YSLAQELAKD IYDEDVRGDS1020
 1021 NDDEDAIEMA IEHVRDRPAS LRKVVLDEYL ASKKRENKKE TYSNIIRELS CGFQDWRIPF1080
 1081 KEPSPDEEFY MISGETEDTI AEGRIVQASV RRLQNGRAIC VLDSGLTGML MKEDFSDDGR1140
 1141 DIVDLADQLK EGDILTCKIK SIQKQRYQVF LICKESEMRN NRHQHNQNVD AYYHEDRNSL1200
 1201 QLVKEKARKE KELVRKHFKS RMIVHPRFQN ITADQATEYL SDKDFGESIV RPSSRGLNFL1260
 1261 TLTLKIYDGV YAHKEIAEGG KENKDITSLQ CIGKTLTIGE DTFEDLDEVM DRYVDPLVSH1320
 1321 LKTMLNYRKF RKGTKSEVDD LLRIEKGENP SRIVYCFGIS HEHPGTFILS YIRSTNPHHE1380
 1381 YIGLYPKGFK FRKRMFEDID RLVAYFQRHI DDPLQESAPS IRSIAAKVPM RSPADHGSSG1440
 1441 GSGWGSSQSE GGWKGNSDRS GSGRGGEYRN GGGRDGHPSG APRPYGGRGR GRGRGRRDDM1500
 1501 NSDRQDGNGD WGNNDTGTAD GGWGNSGGGG WGSESAGKKT GGGSTGGWGS ESGGNKSDGA1560
 1561 GSWGSGSGGG GSGGWGNDSG GKKSSEDGGF GSGSGGGGSD WGNESGGKKS SADGGWGSES1620
 1621 GGKKSDGEGG WGNEPSSRKS DGGGGGW

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
nucleic acid binding	3.87899047526266	bayes_pls_golite062009
DNA binding	3.47278447192966	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	2.90653390639682	bayes_pls_golite062009
binding	2.63617204791771	bayes_pls_golite062009
telomeric DNA binding	2.51555240517937	bayes_pls_golite062009
single-stranded telomeric DNA binding	2.42617682290608	bayes_pls_golite062009
structural constituent of ribosome	2.13063800565247	bayes_pls_golite062009
transcription regulator activity	2.10110937001387	bayes_pls_golite062009
structural molecule activity	1.9177190829469	bayes_pls_golite062009
structure-specific DNA binding	1.81524862921454	bayes_pls_golite062009
single-stranded DNA binding	1.62996999055328	bayes_pls_golite062009
excinuclease ABC activity	1.24466762466323	bayes_pls_golite062009
DNA-directed RNA polymerase activity	1.19766815287926	bayes_pls_golite062009
RNA polymerase activity	1.19766815287926	bayes_pls_golite062009
ribonuclease activity	1.19236946227657	bayes_pls_golite062009
endonuclease activity	0.991569665925888	bayes_pls_golite062009
damaged DNA binding	0.95191912850966	bayes_pls_golite062009
transcription factor activity	0.937752547283357	bayes_pls_golite062009
sequence-specific DNA binding	0.76825863122436	bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters	0.708753843279937	bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	0.598360955770972	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.583085644017496	bayes_pls_golite062009
nuclease activity	0.57381531077345	bayes_pls_golite062009
translation regulator activity	0.31332179848255	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.263197317040851	bayes_pls_golite062009
deoxyribonuclease activity	0.24906263529692	bayes_pls_golite062009
translation initiation factor activity	0.2080607201312	bayes_pls_golite062009
RNA binding	0.18502033889261	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	0.125256208482441	bayes_pls_golite062009
telomerase inhibitor activity	0.111973370145519	bayes_pls_golite062009
exoribonuclease activity	0.109774918833391	bayes_pls_golite062009
DNA-directed DNA polymerase activity	0.09423425042945	bayes_pls_golite062009
protein binding	0.0528188351789111	bayes_pls_golite062009
DNA polymerase activity	0.0189279348688405	bayes_pls_golite062009
endoribonuclease activity	0.016619833072142	bayes_pls_golite062009
chromatin binding	0.0075451629397203	bayes_pls_golite062009

No functions predicted.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..190]	MSA	2.038996	View MSA. No confident structure predictions are available.
2	View Details	[191..311]	deduced	N/A	No confident structure predictions are available.
3	View Details	[312..1186]	PSI-BLAST	1000.0	No description for 2oceA was found.
4	View Details	[1187..1331]	FFAS03	1.7	No description for 2bbuA was found.
5	View Details	[1332..1647]	PSI-BLAST	51.0	No description for 1y0fB was found.

Protein Overview: gi|42562972

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: