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Protein Overview: gi|42562972

General Information:
Name(s) found: gi|42562972 [NCBI NR]
Description(s) found:
Found 7 descriptions.
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  • gi|42562972|ref|NP_176723.3| GTB1; RNA binding / hydrolase, acting on ester bonds / transcription elongation regulator [Arabidopsis thaliana] [NCBI NR]
    • Organism: Arabidopsis thaliana
    Length: 1647 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: chromatin assembly or disassembly [ISS]
    transcription initiation [ISS]
    Molecular Function: hydrolase activity, acting on ester bonds [IEA]
    transcription elongation regulator activity [IEA]
    RNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARNAISDDE EDHELEDDDG EPVHGDPAEH DENDDEEDDD DVGNEYENDG FIVNDEDEEE  60
   61 EEEEDEERKD SDEERQKKKK KRKKKDEGLD EDDYLLLQDN NVKFKKRQYK RLKKAQREQG 120
  121 NGQGESSDDE FDSRGGTRRS AEDKIKDRLF DDVDVDDPPD DVGDEEDLVV EEDVVGSEDE 180
  181 MADFIVDEDD EHGPPKRGNS KKKKYRQGSD ITAMRDANEI FGDVDELLTI RKKGLASNQR 240
  241 MERRLEDEFE PTVLSEKYMT GNDDEIRQLD IPERMQISEE STGSPPVDEI SIEEESNWIY 300
  301 AQLASQLRES DGTFDGRGFS VNKDDIAKFL ELHHVQKLEI PFIAMYRKEQ CRSLLDTGDF 360
  361 DGANQGKKPE TKWHKVFWMI HDLDKKWLLL RKRKMALHGY YTKRYEEESR RVYDETRLNL 420
  421 NQYLFESVIK SLKVAETERE VDDVDSKFNL HFPPGEIGVD EGQYKRPKRK SQYSICSKAG 480
  481 LWEVANKFGY SAEQLGLALS LEKLVDELED AKETPEEMAK NFVCAMFENS LAVLKGARHM 540
  541 AAVEISCEPS VKKYVRGIYM ENAVVSTSPT ADGNTVIDSF HQFSGIKWLR EKPLSKFEGA 600
  601 QWLLIQKGEE EKLLQVTFKL PENYMNRLIS DCNEHYLSVG VSKYAQLWNE QRKLILEDAL 660
  661 HAFLLPSMEK EARSLLTSRA KSRLLSEYGQ ALWNKVSAGP YQKKEMDINL DEEAAPRVMA 720
  721 CCWGPGKPPN TFVMLDSSGE VLDVLYAGSL TSRSQNVNDQ QRKKSDQDRV LKFMMDHQPH 780
  781 VVALGAVNLS CTRLKDDIYE VIFQMVEEKP RDVGHGMDDL SIVYVDESLP RLYENSRISG 840
  841 EQLPQQSGNV RRAVALGRYL QNPLAMVATL CGPGREILSW KLHPLENFLQ LDEKYGMVEQ 900
  901 VMVDITNQVG IDINLAASHD WFFSPLQFIS GLGPRKAASL QRSLVRAGSI FVRKDLIMHG 960
  961 LGKKVFVNAA GFLRIRRSGL AASSSQFIDL LDDTRIHPES YSLAQELAKD IYDEDVRGDS1020
 1021 NDDEDAIEMA IEHVRDRPAS LRKVVLDEYL ASKKRENKKE TYSNIIRELS CGFQDWRIPF1080
 1081 KEPSPDEEFY MISGETEDTI AEGRIVQASV RRLQNGRAIC VLDSGLTGML MKEDFSDDGR1140
 1141 DIVDLADQLK EGDILTCKIK SIQKQRYQVF LICKESEMRN NRHQHNQNVD AYYHEDRNSL1200
 1201 QLVKEKARKE KELVRKHFKS RMIVHPRFQN ITADQATEYL SDKDFGESIV RPSSRGLNFL1260
 1261 TLTLKIYDGV YAHKEIAEGG KENKDITSLQ CIGKTLTIGE DTFEDLDEVM DRYVDPLVSH1320
 1321 LKTMLNYRKF RKGTKSEVDD LLRIEKGENP SRIVYCFGIS HEHPGTFILS YIRSTNPHHE1380
 1381 YIGLYPKGFK FRKRMFEDID RLVAYFQRHI DDPLQESAPS IRSIAAKVPM RSPADHGSSG1440
 1441 GSGWGSSQSE GGWKGNSDRS GSGRGGEYRN GGGRDGHPSG APRPYGGRGR GRGRGRRDDM1500
 1501 NSDRQDGNGD WGNNDTGTAD GGWGNSGGGG WGSESAGKKT GGGSTGGWGS ESGGNKSDGA1560
 1561 GSWGSGSGGG GSGGWGNDSG GKKSSEDGGF GSGSGGGGSD WGNESGGKKS SADGGWGSES1620
 1621 GGKKSDGEGG WGNEPSSRKS DGGGGGW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..190] MSA 2.038996 View MSA. No confident structure predictions are available.
    2 View Details [191..311] deduced N/A No confident structure predictions are available.
    3 View Details [312..1186] PSI-BLAST 1000.0 No description for 2oceA was found.
    4 View Details [1187..1331] FFAS03 1.7 No description for 2bbuA was found.
    5 View Details [1332..1647] PSI-BLAST 51.0 No description for 1y0fB was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • nucleic acid binding
    		•  3.87899047526266 bayes_pls_golite062009
  • DNA binding
    		•  3.47278447192966 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  2.90653390639682 bayes_pls_golite062009
  • binding
    		•  2.63617204791771 bayes_pls_golite062009
  • telomeric DNA binding
    		•  2.51555240517937 bayes_pls_golite062009
  • single-stranded telomeric DNA binding
    		•  2.42617682290608 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.13063800565247 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.10110937001387 bayes_pls_golite062009
  • structural molecule activity
    		•  1.9177190829469 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.81524862921454 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  1.62996999055328 bayes_pls_golite062009
  • excinuclease ABC activity
    		•  1.24466762466323 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  1.19766815287926 bayes_pls_golite062009
  • RNA polymerase activity
    		•  1.19766815287926 bayes_pls_golite062009
  • ribonuclease activity
    		•  1.19236946227657 bayes_pls_golite062009
  • endonuclease activity
    		•  0.991569665925888 bayes_pls_golite062009
  • damaged DNA binding
    		•  0.95191912850966 bayes_pls_golite062009
  • transcription factor activity
    		•  0.937752547283357 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.76825863122436 bayes_pls_golite062009
  • endoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.708753843279937 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.598360955770972 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.583085644017496 bayes_pls_golite062009
  • nuclease activity
    		•  0.57381531077345 bayes_pls_golite062009
  • translation regulator activity
    		•  0.31332179848255 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.263197317040851 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  0.24906263529692 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.2080607201312 bayes_pls_golite062009
  • RNA binding
    		•  0.18502033889261 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.125256208482441 bayes_pls_golite062009
  • telomerase inhibitor activity
    		•  0.111973370145519 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.109774918833391 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.09423425042945 bayes_pls_golite062009
  • protein binding
    		•  0.0528188351789111 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.0189279348688405 bayes_pls_golite062009
  • endoribonuclease activity
    		•  0.016619833072142 bayes_pls_golite062009
  • chromatin binding
    		•  0.0075451629397203 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle