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Protein Overview: gi|42572301

General Information:
Name(s) found: gi|42572301 [NCBI NR]
Description(s) found:
Found 7 descriptions.
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  • gi|42572301|ref|NP_974246.1| GTP cyclohydrolase I [Arabidopsis thaliana] [NCBI NR]
    • Organism: Arabidopsis thaliana
    Length: 466 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: tetrahydrofolate biosynthetic process [IEA]
    Molecular Function: GTP cyclohydrolase I activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTKDEGCLN LELDIGMKNG CIELAFEHQP ETLAIQDAVK LLLQGLHEDV NREGIKKTPF  60
   61 RVAKALREGT RGYKQKVKDY VQSALFPEAG LDEGVGQAGG VGGLVVVRDL DHYSYCESCL 120
  121 LPFHVKCHIG YVPSGQRVLG LSKFSRVTDV FAKRLQDPQR LADDICSALQ HWVKPAGVAV 180
  181 VLECSHIHFP SLDLDSLNLS SHRGFVKLLV SSGSGVFEDE SSNLWGEFQS FLMFKGVKTQ 240
  241 ALCRNGSSVK EWCPSVKSSS KLSPEVDPEM VSAVVSILKS LGEDPLRKEL IATPTRFLKW 300
  301 MLNFQRTNLE MKLNSFNPAK VNGEVKEKRL HCELNMPFWS MCEHHLLPFY GVVHIGYFCA 360
  361 EGSNPNPVGS SLMKAIVHFY GFKLQVQERM TRQIAETLSP LVGGDVIVVA EAGHTCMISR 420
  421 GIEKFGSSTA TIAVLGRFSS DNSARAMFLD KIHTTNALKT ESSSPF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..244] FFAS03 8.41 Structure of GTP cyclohydrolase I from Thermus thermophilus HB8
    2 View Details [245..466] PSI-BLAST 80.39794 GTP cyclohydrolase I

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • GTP cyclohydrolase I activity
    		•  4.58215881457764 bayes_pls_golite062009
  • cyclohydrolase activity
    		•  3.1225900680321 bayes_pls_golite062009
  • GTP cyclohydrolase activity
    		•  2.816522292063 bayes_pls_golite062009
  • 6-pyruvoyltetrahydropterin synthase activity
    		•  2.34489533040902 bayes_pls_golite062009
  • catalytic activity
    		•  2.02879677696451 bayes_pls_golite062009
  • dihydroneopterin aldolase activity
    		•  1.4000306436633 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  1.2538657804327 bayes_pls_golite062009
  • binding
    		•  1.23408359924301 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  0.627364990614658 bayes_pls_golite062009
  • protein binding
    		•  0.316566321438364 bayes_pls_golite062009
    2
    Term Confidence Notes
  • GTP cyclohydrolase I activity
    		•  5.27071565931386 bayes_pls_golite062009
  • cyclohydrolase activity
    		•  3.66553359909123 bayes_pls_golite062009
  • GTP cyclohydrolase activity
    		•  3.44912994722205 bayes_pls_golite062009
  • 6-pyruvoyltetrahydropterin synthase activity
    		•  2.94513271787536 bayes_pls_golite062009
  • catalytic activity
    		•  2.20788162511962 bayes_pls_golite062009
  • dihydroneopterin aldolase activity
    		•  1.96466418682643 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  1.73101699306211 bayes_pls_golite062009
  • binding
    		•  1.19587307204017 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  0.974891318710762 bayes_pls_golite062009
  • protein binding
    		•  0.298277659609786 bayes_pls_golite062009
  • urate oxidase activity
    		•  0.0294957696532921 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle