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Protein Overview: gi|1827806, gi|2...

General Information:
Name(s) found: gi|5822045 [NCBI NR]
gi|5542270 [NCBI NR]
gi|5542120 [NCBI NR]
gi|2982090 [NCBI NR]
gi|2982089 [NCBI NR]
gi|1827806 [NCBI NR]
gi|1827805 [NCBI NR]
gi|157831324 [NCBI NR]
gi|157830332 [NCBI NR]
Description(s) found:
Found 19 descriptions.
SHOW ALL
  • gi|5822045|pdb|1DIC|A Chain A, Structure Of 3,4-Dichloroisocoumarin-Inhibited Factor D [NCBI NR]
  • gi|5542270|pdb|1HFD| Chain , Human Complement Factor D In A P21 Crystal Form [NCBI NR]
  • gi|5542120|pdb|1BIO| Chain , Human Complement Factor D In Complex With Isatoic Anhydride Inhibitor [NCBI NR]
  • gi|2982090|pdb|1DFP|B Chain B, Factor D Inhibited By Diisopropyl Fluorophosphate [NCBI NR]
  • gi|2982089|pdb|1DFP|A Chain A, Factor D Inhibited By Diisopropyl Fluorophosphate [NCBI NR]
  • gi|1827806|pdb|1DSU|B Chain B, Human Factor D, Complement Activating Enzyme [NCBI NR]
  • gi|1827805|pdb|1DSU|A Chain A, Human Factor D, Complement Activating Enzyme [NCBI NR]
  • gi|157831324|pdb|1HFD|A Chain A, Human Complement Factor D In A P21 Crystal Form [NCBI NR]
  • gi|157830332|pdb|1BIO|A Chain A, Human Complement Factor D In Complex With Isatoic Anhydride Inhibitor [NCBI NR]
    • Organism: Homo sapiens
    Length: 228 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILGGREAEAH ARPYMASVQL NGAHLCGGVL VAEQWVLSAA HCLEDAADGK VQVLLGAHSL  60
   61 SQPEPSKRLY DVLRAVPHPD SQPDTIDHDL LLLQLSEKAT LGPAVRPLPW QRVDRDVAPG 120
  121 TLCDVAGWGI VNHAGRRPDS LQHVLLPVLD RATCNRRTHH DGAITERLMC AESNRRDSCK 180
  181 GDSGGPLVCG GVLEGVVTSG SRVCGNRKKP GIYTRVASYA AWIDSVLA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. gi|112491310 gi|1827806, gi|2...

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..228] PSI-BLAST 63.39794 MUTANT OF FACTOR D WITH ENHANCED CATALYTIC ACTIVITY

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  5.91209560688646 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  5.52773635813967 bayes_pls_golite062009
  • serine hydrolase activity
    		•  5.5105092190926 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  5.49703869306079 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  5.39623690248556 bayes_pls_golite062009
  • endopeptidase activity
    		•  5.32070018460528 bayes_pls_golite062009
  • hydrolase activity
    		•  4.40346950809697 bayes_pls_golite062009
  • fucose binding
    		•  3.5000591397073 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  2.01328116441763 bayes_pls_golite062009
  • calcium-dependent protein binding
    		•  1.96509840108953 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.73928761064649 bayes_pls_golite062009
  • DNA binding
    		•  1.61536775064425 bayes_pls_golite062009
  • heparin binding
    		•  1.48285358055737 bayes_pls_golite062009
  • thrombospondin receptor activity
    		•  1.44312413043539 bayes_pls_golite062009
  • catalytic activity
    		•  1.40927913545237 bayes_pls_golite062009
  • polysaccharide binding
    		•  1.34665327732001 bayes_pls_golite062009
  • binding
    		•  1.30738106455622 bayes_pls_golite062009
  • protein binding
    		•  1.30414885212044 bayes_pls_golite062009
  • receptor activity
    		•  1.10676631226741 bayes_pls_golite062009
  • serine-type aminopeptidase activity
    		•  0.964413112640311 bayes_pls_golite062009
  • signal transducer activity
    		•  0.885246794092463 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.885246794092463 bayes_pls_golite062009
  • growth factor activity
    		•  0.848900101748605 bayes_pls_golite062009
  • receptor binding
    		•  0.79054390509229 bayes_pls_golite062009
  • calcium ion binding
    		•  0.753095272942721 bayes_pls_golite062009
  • sodium channel regulator activity
    		•  0.30724450617383 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle