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View Structure Prediction Details

Protein: gi|1827806, gi|2...
Organism: Homo sapiens
Length: 228 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1827806, gi|2....

Description E-value Query
Range
Subject
Range
gi|87130885 - gi|87130885|gb|ABD24064.1| intein-trypsinogen fusion protein [synthetic construct]
246.0 [0..1] [228..164]
gi|149065391, gi... - gi|149065391|gb|EDM15467.1| rCG64545 [Rattus norvegicus], gi|109473340|ref|XP_001068290.1| PREDICTED...
244.0 [0..1] [228..24]
gi|16716569, gi|... - gi|66267389|gb|AAH94921.1| Protease, serine, 1 (trypsin 1) [Mus musculus], gi|3916748|gb|AAC79093.1|...
243.0 [0..1] [228..24]
gi|68379391 - gi|68379391|ref|XP_698179.1| PREDICTED: hypothetical protein [Danio rerio]
242.0 [0..1] [227..288]

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Predicted Domain #1
Region A:
Residues: [1-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILGGREAEAH ARPYMASVQL NGAHLCGGVL VAEQWVLSAA HCLEDAADGK VQVLLGAHSL  60
   61 SQPEPSKRLY DVLRAVPHPD SQPDTIDHDL LLLQLSEKAT LGPAVRPLPW QRVDRDVAPG 120
  121 TLCDVAGWGI VNHAGRRPDS LQHVLLPVLD RATCNRRTHH DGAITERLMC AESNRRDSCK 180
  181 GDSGGPLVCG GVLEGVVTSG SRVCGNRKKP GIYTRVASYA AWIDSVLA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.39794
Match: 1dstA
Description: MUTANT OF FACTOR D WITH ENHANCED CATALYTIC ACTIVITY
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 5.91209560688646 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 5.52773635813967 bayes_pls_golite062009
serine hydrolase activity 5.5105092190926 bayes_pls_golite062009
serine-type peptidase activity 5.49703869306079 bayes_pls_golite062009
serine-type endopeptidase activity 5.39623690248556 bayes_pls_golite062009
endopeptidase activity 5.32070018460528 bayes_pls_golite062009
hydrolase activity 4.40346950809697 bayes_pls_golite062009
fucose binding 3.5000591397073 bayes_pls_golite062009
glycosaminoglycan binding 2.01328116441763 bayes_pls_golite062009
calcium-dependent protein binding 1.96509840108953 bayes_pls_golite062009
nucleic acid binding 1.73928761064649 bayes_pls_golite062009
DNA binding 1.61536775064425 bayes_pls_golite062009
heparin binding 1.48285358055737 bayes_pls_golite062009
thrombospondin receptor activity 1.44312413043539 bayes_pls_golite062009
catalytic activity 1.40927913545237 bayes_pls_golite062009
polysaccharide binding 1.34665327732001 bayes_pls_golite062009
binding 1.30738106455622 bayes_pls_golite062009
protein binding 1.30414885212044 bayes_pls_golite062009
receptor activity 1.10676631226741 bayes_pls_golite062009
serine-type aminopeptidase activity 0.964413112640311 bayes_pls_golite062009
signal transducer activity 0.885246794092463 bayes_pls_golite062009
molecular transducer activity 0.885246794092463 bayes_pls_golite062009
growth factor activity 0.848900101748605 bayes_pls_golite062009
receptor binding 0.79054390509229 bayes_pls_golite062009
calcium ion binding 0.753095272942721 bayes_pls_golite062009
sodium channel regulator activity 0.30724450617383 bayes_pls_golite062009

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