| Protein: | FBpp0310357, gfA... |
| Organism: | Drosophila melanogaster |
| Length: | 560 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0310357, gfA....
| Description | E-value | Query Range |
Subject Range |
|
|
497.0 | [0..23] | [559..1] |
|
Region A: Residues: [1-365] |
1 11 21 31 41 51
| | | | | |
1 MKKPSRSRPD NPSCPGQDRT RSMSFPQPHS LPEATANGGR MLVYGLGLLI MIPACAAGPH 60
61 EKRLLHALLD NYNSLERPVV NESDPLQLSF GLTLMQIIDV DEKNQLLITN IWLKLEWNDM 120
121 NLRWNSSEFG GVRDLRIPPH RLWKPDVLMY NSADEGFDGT YATNVVVRNN GSCLYVPPGI 180
181 FKSTCKIDIT WFPFDDQRCE MKFGSWTYDG FQLDLQLQDE AGGDISSFIT NGEWDLLGVP 240
241 GKRNEIYYNC CPEPYIDITF AILIRRKTLY YFFNLIVPCV LIASMALLGF TLPPDSGEKL 300
301 SLGVTILLSL TVFLNMVAET MPATSDAVPL LGTYFNCIMF MVASSVVSTI LILNYHHRNP 360
361 DTHEM
|
| Detection Method: |  |
| Confidence: | 83.39794 |
| Match: | 2bg9A |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [366-560] |
1 11 21 31 41 51
| | | | | |
1 SEWIRVIFLY WLPCILRMQR PGQVGYECPP PPSSSSSSAS GEKKQQIQNV ELKERSSKSL 60
61 LANVLDIDDD FRCNHRCASA TLPHQPTYYR TMYRQGDDGS VGPVGPAGPV VDGRLHEAIS 120
121 HTCLTSSAEY ELALILKELR WITEQLKKED ETSDITRDWK FAAMVVDRLC LIIFTLFTII 180
181 ATLAVLFSAP HFIFP
|
| Detection Method: | |
| Confidence: | 44.30103 |
| Match: | 1oedB |
| Description: | Acetylcholine receptor protein, beta chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| acetylcholine binding | 13.9752632471881 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 13.7533645836795 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 13.1511875247796 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 11.9525876011069 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 11.7813202122163 | bayes_pls_golite062009 |
| cation channel activity | 11.7442066737514 | bayes_pls_golite062009 |
| ion channel activity | 11.1753684044644 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 11.0903806681397 | bayes_pls_golite062009 |
| channel activity | 11.0903806681397 | bayes_pls_golite062009 |
| gated channel activity | 11.0397691626728 | bayes_pls_golite062009 |
| substrate-specific channel activity | 10.9375522860542 | bayes_pls_golite062009 |
| ligand-gated channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| amine binding | 9.11982124959723 | bayes_pls_golite062009 |
| chloride channel regulator activity | 9.10587892909341 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 7.22265353460749 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 7.19173677417054 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 6.7875346065164 | bayes_pls_golite062009 |
| transmembrane receptor activity | 5.4080353535498 | bayes_pls_golite062009 |
| receptor activity | 5.11329651194787 | bayes_pls_golite062009 |
| transporter activity | 5.11262082564788 | bayes_pls_golite062009 |
| transmembrane transporter activity | 5.03439798256257 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 4.91314874981447 | bayes_pls_golite062009 |
| neurotransmitter binding | 4.25797760547212 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 4.15404686068319 | bayes_pls_golite062009 |
| signal transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| molecular transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| binding | 2.4916526322278 | bayes_pls_golite062009 |
| adenylate cyclase binding | 2.44136378171826 | bayes_pls_golite062009 |
| beta-amyloid binding | 2.25766805801029 | bayes_pls_golite062009 |
| 1.68370717591127 | bayes_pls_golite062009 | |
| channel regulator activity | 1.66978990310631 | bayes_pls_golite062009 |
| protein binding | 1.45740893920165 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.42422063123689 | bayes_pls_golite062009 |
| serotonin binding | 1.33584589886834 | bayes_pls_golite062009 |
| serotonin-activated cation-selective channel activity | 1.31324203158511 | bayes_pls_golite062009 |
| toxin binding | 1.03329843925063 | bayes_pls_golite062009 |
| drug binding | 0.64715018605883 | bayes_pls_golite062009 |
| kinase binding | 0.365355763029699 | bayes_pls_golite062009 |
| protein kinase binding | 0.350601457777817 | bayes_pls_golite062009 |
