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View Structure Prediction Details

Protein: RNF10
Organism: Homo sapiens
Length: 811 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNF10.

Description E-value Query
Range
Subject
Range
gi|30584221, gi|... - gi|61371072|gb|AAX43604.1| ring finger protein 10 [synthetic construct], gi|30584221|gb|AAP36359.1| ...
0.0 [1..811] [1..811]
gi|21619487 - gi|21619487|gb|AAH31596.1| Ring finger protein 10 [Homo sapiens]
0.0 [1..811] [1..811]
gi|114647308, gi... - gi|114647308|ref|XP_001161948.1| PREDICTED: ring finger protein 10 isoform 13 [Pan troglodytes], gi|...
0.0 [1..811] [1..811]
RNF10_RAT - RING finger protein 10 OS=Rattus norvegicus GN=Rnf10 PE=2 SV=1
0.0 [1..811] [1..802]
RNF10_BOVIN - RING finger protein 10 OS=Bos taurus GN=RNF10 PE=2 SV=1
0.0 [1..811] [1..810]
gi|74144838 - gi|74144838|dbj|BAE27391.1| unnamed protein product [Mus musculus]
0.0 [1..811] [1..804]

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Predicted Domain #1
Region A:
Residues: [1-207]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLSSPNAAA TASDMDKNSG SNSSSASSGS SKGQQPPRSA SAGPAGESKP KSDGKNSSGS  60
   61 KRYNRKRELS YPKNESFNNQ SRRSSSQKSK TFNKMPPQRG GGSSKLFSSS FNGGRRDEVA 120
  121 EAQRAEFSPA QFSGPKKINL NHLLNFTFEP RGQTGHFEGS GHGSWGKRNK WGHKPFNKEL 180
  181 FLQANCQFVV SEDQDYTAHF ADPDTLV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [208-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NWDFVEQVRI CSHEVPSCPI CLYPPTAAKI TRCGHIFCWA CILHYLSLSE KTWSKCPICY  60
   61 SSVHKKDLKS VVATESHQYV VGDTITMQLM KREKGVLVAL PKSKWMNVDH PIHLGDEQHS 120
  121 QYSKLLLA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.0
Match: 1rmdA
Description: RAG1 DIMERIZATION DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 2.64803540957326 bayes_pls_golite062009
binding 2.14721962003828 bayes_pls_golite062009
transcription regulator activity 1.68475305605912 bayes_pls_golite062009
nucleic acid binding 1.14817467304431 bayes_pls_golite062009
DNA binding 1.04821660471647 bayes_pls_golite062009
small conjugating protein ligase activity 0.628952571387495 bayes_pls_golite062009
transcription activator activity 0.546784009980947 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.491915833175877 bayes_pls_golite062009
chromatin binding 0.48807894940058 bayes_pls_golite062009
ligase activity 0.34187399168736 bayes_pls_golite062009
transcription factor activity 0.256724934540426 bayes_pls_golite062009
transcription factor binding 0.25479994691323 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.15369897412662 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
sequence-specific DNA binding 0.017536022609566 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [336-502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKEQVLHRVV LEEKVALEQQ LAEEKHTPES CFIEAAIQEL KTREEALSGL AGSRREVTGV  60
   61 VAALEQLVLM APLAKESVFQ PRKGVLEYLS AFDEETTEVC SLDTPSRPLA LPLVEEEEAV 120
  121 SEPEPEGLPE ACDDLELADD NLKEGTICTE SSQQEPITKS GFTRLSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [503-626]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPCYYFYQAE DGQHMFLHPV NVRCLVREYG SLERSPEKIS ATVVEIAGYS MSEDVRQRHR  60
   61 YLSHLPLTCE FSICELALQP PVVSKETLEM FSDDIEKRKR QRQKKAREER RRERRIEIEE 120
  121 NKKQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [627-811]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKYPEVHIPL ENLQQFPAFN SYTCSSDSAL GPTSTEGHGA LSISPLSRSP GSHADFLLTP  60
   61 LSPTASQGSP SFCVGSLEED SPFPSFAQML RVGKAKADVW PKTAPKKDEN SLVPPAPVDS 120
  121 DGESDNSDRV PVPSFQNSFS QAIEAAFMKL DTPATSDPLS EEKGGKKRKK QKQKLLFSTS 180
  181 VVHTK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.17
Match: 2fj7I
Description: No description for 2fj7I was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle