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View Structure Prediction Details

Protein: RNF10
Organism: Homo sapiens
Length: 811 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNF10.

Description E-value Query
Range
Subject
Range
gi|30584221, gi|... - gi|61371072|gb|AAX43604.1| ring finger protein 10 [synthetic construct], gi|30584221|gb|AAP36359.1| ...
0.0 [1..811] [1..811]
gi|21619487 - gi|21619487|gb|AAH31596.1| Ring finger protein 10 [Homo sapiens]
0.0 [1..811] [1..811]
gi|114647308, gi... - gi|114647308|ref|XP_001161948.1| PREDICTED: ring finger protein 10 isoform 13 [Pan troglodytes], gi|...
0.0 [1..811] [1..811]
RNF10_RAT - RING finger protein 10 OS=Rattus norvegicus GN=Rnf10 PE=2 SV=1
0.0 [1..811] [1..802]
RNF10_BOVIN - RING finger protein 10 OS=Bos taurus GN=RNF10 PE=2 SV=1
0.0 [1..811] [1..810]
gi|74144838 - gi|74144838|dbj|BAE27391.1| unnamed protein product [Mus musculus]
0.0 [1..811] [1..804]

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Predicted Domain #1
Region A:
Residues: [1-207]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLSSPNAAA TASDMDKNSG SNSSSASSGS SKGQQPPRSA SAGPAGESKP KSDGKNSSGS  60
   61 KRYNRKRELS YPKNESFNNQ SRRSSSQKSK TFNKMPPQRG GGSSKLFSSS FNGGRRDEVA 120
  121 EAQRAEFSPA QFSGPKKINL NHLLNFTFEP RGQTGHFEGS GHGSWGKRNK WGHKPFNKEL 180
  181 FLQANCQFVV SEDQDYTAHF ADPDTLV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [208-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NWDFVEQVRI CSHEVPSCPI CLYPPTAAKI TRCGHIFCWA CILHYLSLSE KTWSKCPICY  60
   61 SSVHKKDLKS VVATESHQYV VGDTITMQLM KREKGVLVAL PKSKWMNVDH PIHLGDEQHS 120
  121 QYSKLLLA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.0
Match: 1rmdA
Description: RAG1 DIMERIZATION DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 2.64803540957326 bayes_pls_golite062009
binding 2.14721962003828 bayes_pls_golite062009
transcription regulator activity 1.68475305605912 bayes_pls_golite062009
nucleic acid binding 1.14817467304431 bayes_pls_golite062009
DNA binding 1.04821660471647 bayes_pls_golite062009
small conjugating protein ligase activity 0.628952571387495 bayes_pls_golite062009
transcription activator activity 0.546784009980947 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.491915833175877 bayes_pls_golite062009
chromatin binding 0.48807894940058 bayes_pls_golite062009
ligase activity 0.34187399168736 bayes_pls_golite062009
transcription factor activity 0.256724934540426 bayes_pls_golite062009
transcription factor binding 0.25479994691323 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.15369897412662 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
sequence-specific DNA binding 0.017536022609566 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [336-502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKEQVLHRVV LEEKVALEQQ LAEEKHTPES CFIEAAIQEL KTREEALSGL AGSRREVTGV  60
   61 VAALEQLVLM APLAKESVFQ PRKGVLEYLS AFDEETTEVC SLDTPSRPLA LPLVEEEEAV 120
  121 SEPEPEGLPE ACDDLELADD NLKEGTICTE SSQQEPITKS GFTRLSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.336 0.049 protein binding a.74.1 Cyclin-like
View Download 0.444 0.023 metal ion binding a.126.1 Serum albumin-like
View Download 0.353 0.002 zinc ion binding a.2.3 Chaperone J-domain
View Download 0.343 N/A N/A a.185.1 Gametocyte protein Pfg27
View Download 0.319 N/A N/A a.74.1 Cyclin-like

Predicted Domain #4
Region A:
Residues: [503-626]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPCYYFYQAE DGQHMFLHPV NVRCLVREYG SLERSPEKIS ATVVEIAGYS MSEDVRQRHR  60
   61 YLSHLPLTCE FSICELALQP PVVSKETLEM FSDDIEKRKR QRQKKAREER RRERRIEIEE 120
  121 NKKQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [627-811]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKYPEVHIPL ENLQQFPAFN SYTCSSDSAL GPTSTEGHGA LSISPLSRSP GSHADFLLTP  60
   61 LSPTASQGSP SFCVGSLEED SPFPSFAQML RVGKAKADVW PKTAPKKDEN SLVPPAPVDS 120
  121 DGESDNSDRV PVPSFQNSFS QAIEAAFMKL DTPATSDPLS EEKGGKKRKK QKQKLLFSTS 180
  181 VVHTK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.17
Match: 2fj7I
Description: No description for 2fj7I was found.

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Created and Maintained by: Michael Riffle