YRC Public Data Repository - Protein Structure Prediction

Protein:	MALF_ECOLI
Organism:	Escherichia coli
Length:	514 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MALF_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|208805643, gi... - gi\|208805643\|ref\|ZP_03247980.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Escheri... gi\|208733973, gi... - gi\|208812696\|ref\|ZP_03254025.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Escheri... gi\|208818700, gi... - gi\|208818700\|ref\|ZP_03259020.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Escheri... gi\|209162202, gi... - gi\|209400802\|ref\|YP_002273554.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Escher... gi\|13364493, gi\|... - gi\|15834270\|ref\|NP_313043.1\| maltose transporter membrane protein [Escherichia coli O157:H7 str. Sak... gi\|189001744, gi... - gi\|189001744\|gb\|EDU70730.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Escherichia... gi\|168784629, gi... - gi\|189374881\|gb\|EDU93297.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Escherichia... gi\|189379150, gi... - gi\|189379150\|gb\|EDU97566.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Escherichia... gi\|195935800 - gi\|195935800\|ref\|ZP_03081182.1\| maltose transporter membrane protein [Escherichia coli O157:H7 str. ... gi\|168755184, gi... - gi\|189357412\|gb\|EDU75831.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Escherichia... gi\|189368543, gi... - gi\|189368543\|gb\|EDU86959.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Escherichia... gi\|189364309, gi... - gi\|189364309\|gb\|EDU82728.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Escherichia... gi\|187769920, gi... - gi\|187769920\|gb\|EDU33764.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Escherichia... gi\|168750836, gi... - gi\|188015051\|gb\|EDU53173.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Escherichia... gi\|254796035, gi... - gi\|254796035\|ref\|YP_003080872.1\| maltose transporter subunit, membrane component of ABC superfamily ... gi\|25297535, gi\|... - pir\|\|H91255 transport system permease protein MalF ECs5016 [imported] - Escherichia coli (strain O15... gi\|217324846, gi... - gi\|217324846\|ref\|ZP_03440930.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Escheri... MALF_ECO57 - Maltose transport system permease protein MalF OS=Escherichia coli O157:H7 GN=malF PE=3 SV=1	311.0	[0..1]	[514..1]
gi\|226901503, gi... - gi\|237703591\|ref\|ZP_04534072.1\| maltose transporter membrane protein [Escherichia sp. 3_2_53FAA], gi... gi\|115515426, gi... - gi\|117626302\|ref\|YP_859625.1\| maltose transporter membrane protein [Escherichia coli APEC O1], gi\|11... gi\|91075130, gi\|... - gi\|91213556\|ref\|YP_543542.1\| maltose transporter membrane protein [Escherichia coli UTI89], gi\|91075...	311.0	[0..1]	[514..6]
MALF_ECOL6 - Maltose transport system permease protein malF OS=Escherichia coli O6 GN=malF PE=3 SV=1 MALF_ECOL6 - Maltose transport system permease protein MalF OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 70092... gi\|227836102, gi... - gi\|227886961\|ref\|ZP_04004766.1\| maltose transporter membrane protein [Escherichia coli 83972], gi\|22...	310.0	[0..1]	[514..6]
gi\|25297540 - pir\|\|D86096 part of maltose permease, periplasmic [imported] - Escherichia coli (strain O157:H7, sub... gi\|15804626, gi\|... - gi\|15804626\|ref\|NP_290667.1\| maltose transporter membrane protein [Escherichia coli O157:H7 EDL933],...	310.0	[0..1]	[514..1]
MALF_ENTAE - Maltose transport system permease protein MalF OS=Enterobacter aerogenes GN=malF PE=3 SV=1	310.0	[0..1]	[514..1]
gi\|194423739, gi... - gi\|83587127\|ref\|ZP_00925756.1\| COG1175: ABC-type sugar transport systems, permease components [Esche...	309.0	[0..1]	[514..1]
gi\|56384085, gi\|... - gi\|56480534\|ref\|NP_709886.2\| maltose transporter membrane protein [Shigella flexneri 2a str. 301], g... MALF_SHIFL - Maltose transport system permease protein MalF OS=Shigella flexneri GN=malF PE=3 SV=2	308.0	[0..1]	[514..1]
gi\|74314526, gi\|... - gi\|74314526\|ref\|YP_312945.1\| maltose transporter membrane protein [Shigella sonnei Ss046], gi\|738580...	306.0	[0..1]	[514..1]
gi\|47774, gi\|96792 - pir\|\|S20604 inner membrane protein malF - Salmonella typhimurium, gi\|47774\|emb\|CAA38190.1\| malF [Sal... gi\|47774\|emb\|CAA... - malF [Salmonella typhimurium]	300.0	[0..1]	[514..1]
gi\|62130310, gi\|... - gi\|62182677\|ref\|YP_219094.1\| maltose transporter membrane protein [Salmonella enterica subsp. enteri... gi\|167552552, gi... - gi\|205322803\|gb\|EDZ10642.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Salmonella ... gi\|224585994, gi... - gi\|224585994\|ref\|YP_002639793.1\| maltose transport inner membrane protein [Salmonella enterica subsp... gi\|206711185, gi... - gi\|207859382\|ref\|YP_002246033.1\| maltose transporter membrane protein [Salmonella enterica subsp. en... gi\|205274781, gi... - gi\|205355000\|ref\|YP_002228801.1\| maltose transporter membrane protein [Salmonella enterica subsp. en... gi\|205342129, gi... - gi\|205342129\|gb\|EDZ28893.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Salmonella ... gi\|168263455, gi... - gi\|205348012\|gb\|EDZ34643.1\| maltose/maltodextrin ABC transporter, permease protein MalF [Salmonella ...	299.0	[0..1]	[514..1]

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Predicted Domain #1

Region A:
Residues: [1-206]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVIKKKHWW QSDALKWSVL GLLGLLVGYL VVLMYAQGEY LFAITTLILS SAGLYIFANR  60
   61 KAYAWRYVYP GMAGMGLFVL FPLVCTIAIA FTNYSSTNQL TFERAQEVLL DRSWQAGKTY 120
  121 NFGLYPAGDE WQLALSDGET GKNYLSDAFK FGGEQKLQLK ETTAQPEGER ANLRVITQNR 180
  181 QALSDITAIL PDGNKVMMSS LRQFSG

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [207-271]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQPLYTLDGD GTLTNNQSGV KYRPNNQIGF YQSITADGNW GDEKLSPGYT VTTGWKNFTR  60
   61 VFTDE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.823	b.55.1	PH domain-like
View	Download	0.727	b.55.1	PH domain-like
View	Download	0.723	b.61.3	D-aminopeptidase, middle and C-terminal domains
View	Download	0.695	b.55.1	PH domain-like
View	Download	0.672	b.93.1	Epsilon subunit of F1F0-ATP synthase N-terminal domain

Predicted Domain #3

Region A:
Residues: [272-514]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GIQKPFLAIF VWTVVFSLIT VFLTVAVGMV LACLVQWEAL RGKAVYRVLL ILPYAVPSFI  60
   61 SILIFKGLFN QSFGEINMML SALFGVKPAW FSDPTTARTM LIIVNTWLGY PYMMILCMGL 120
  121 LKAIPDDLYE ASAMDGAGPF QNFFKITLPL LIKPLTPLMI ASFAFNFNNF VLIQLLTNGG 180
  181 PDRLGTTTPA GYTDLLVNYT YRIAFEGGGG QDFGLAAAIA TLIFLLVGAL AIVNLKATRM 240
  241 KFD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.30103
Match:	2onkC
Description:	No description for 2onkC was found.

Predicted functions:

Term	Confidence	Notes
maltose transmembrane transporter activity	8.28826189049497	bayes_pls_golite062009
alpha-glucoside transmembrane transporter activity	8.28826189049497	bayes_pls_golite062009
disaccharide transmembrane transporter activity	8.28826189049497	bayes_pls_golite062009
maltose-transporting ATPase activity	8.24190569178573	bayes_pls_golite062009
oligosaccharide-transporting ATPase activity	8.24190569178573	bayes_pls_golite062009
oligosaccharide transmembrane transporter activity	8.24190569178573	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	7.98776119907207	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	7.98726234902655	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	7.98726234902655	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	7.97287417765536	bayes_pls_golite062009
primary active transmembrane transporter activity	7.96249144456164	bayes_pls_golite062009
active transmembrane transporter activity	7.8678894318504	bayes_pls_golite062009
glucoside transmembrane transporter activity	7.52498147729237	bayes_pls_golite062009
maltooligosaccharide-importing ATPase activity	7.32447511329936	bayes_pls_golite062009
ATPase activity, coupled	7.29227234008448	bayes_pls_golite062009
ATPase activity	6.94069583578738	bayes_pls_golite062009
nucleoside-triphosphatase activity	6.59903874016214	bayes_pls_golite062009
pyrophosphatase activity	6.52169210550643	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	6.50067149801529	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	6.5003333073452	bayes_pls_golite062009
sugar transmembrane transporter activity	5.77004935785912	bayes_pls_golite062009
hydrolase activity	4.78607811092587	bayes_pls_golite062009
transporter activity	4.47791794099048	bayes_pls_golite062009
transmembrane transporter activity	4.39634414867723	bayes_pls_golite062009
substrate-specific transporter activity	3.91409799494188	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.86345398417242	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	3.38648305647717	bayes_pls_golite062009
sugar:hydrogen symporter activity	2.72644761294537	bayes_pls_golite062009
cation:sugar symporter activity	2.72644761294537	bayes_pls_golite062009
ion transmembrane transporter activity	2.70116960945763	bayes_pls_golite062009
carbohydrate-importing ATPase activity	2.35016331368678	bayes_pls_golite062009
carbohydrate-transporting ATPase activity	2.32845065117258	bayes_pls_golite062009
solute:hydrogen symporter activity	1.84116772499041	bayes_pls_golite062009
cation transmembrane transporter activity	1.82526327874202	bayes_pls_golite062009
anion transmembrane-transporting ATPase activity	1.56112505527856	bayes_pls_golite062009
sulfate transmembrane-transporting ATPase activity	1.00737155315764	bayes_pls_golite062009
secondary active transmembrane transporter activity	0.96228415837358	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	0.69074662322395	bayes_pls_golite062009
symporter activity	0.483541714040201	bayes_pls_golite062009
solute:cation symporter activity	0.483541714040201	bayes_pls_golite062009
catalytic activity	0.427775057748038	bayes_pls_golite062009
anion transmembrane transporter activity	0.38505555521505	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: