YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|151940852
Organism:	Saccharomyces cerevisiae YJM789
Length:	259 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|151940852.

Description	E-value	Query Range	Subject Range
CWC24 - Essential protein, component of a complex containing Cef1p; has similarity to S. pombe Cwf24p gi\|190405375 - gi\|190405375\|gb\|EDV08642.1\| pre-mRNA splicing factor CWC24 [Saccharomyces cerevisiae RM11-1a] CWC24_YEAST - Pre-mRNA-splicing factor CWC24 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CWC24 PE=... gi\|151940852 - gi\|151940852\|gb\|EDN59234.1\| complexed with cef1p [Saccharomyces cerevisiae YJM789] gi\|207342828 - gi\|207342828\|gb\|EDZ70470.1\| YLR323Cp-like protein [Saccharomyces cerevisiae AWRI1631]	1.0E-53	[1..259]	[1..259]
gi\|21313494, gi\|... - gi\|21313494\|ref\|NP_079801.1\| ring finger protein 113A [Mus musculus], gi\|12844204\|dbj\|BAB26275.1\| un...	2.0E-53	[8..258]	[48..321]
gi\|208968727 - gi\|208968727\|dbj\|BAG74202.1\| ring finger protein 113B [synthetic construct] gi\|119629388, gi... - gi\|14532913\|emb\|CAC42525.1\| OTTHUMP00000018586 [Homo sapiens], gi\|119629388\|gb\|EAX08983.1\| hCG164627...	6.0E-53	[9..259]	[44..316]
gi\|15223384 - gi\|15223384\|ref\|NP_171642.1\| zinc finger (CCCH-type/C3HC4-type RING finger) family protein [Arabidop...	2.0E-48	[3..259]	[43..337]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	4.0E-38	[5..256]	[288..531]
CWC24_SCHPO - Pre-mRNA-splicing factor cwf24 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=cwf24 PE=1 ... cwf24 - GCN5-related N acetyltransferase	4.0E-37	[2..259]	[43..314]

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Predicted Domain #1

Region A:
Residues: [1-168]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRKRLVNKS SSDEKNQKKR QKINFSEEKL VASDEEKGSS DLMSLAKSGN SRTLQLSHEN  60
   61 EGKLQKKGED LDKYTLTVND DSTKEDLLNF ERKELAEKAK KRRPSDDNEL VLNMSGKNKR 120
  121 LTKQINQPTN IRTTVLMDFQ PDVCKDYKQT GYCGYGDSCK FLHSRDDF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [169-259]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTGWKLNQEW NADKEDSKAV TLDLEKIPFK CTLCKEDYKS PVVTNCGHYF CGSCFAKDMK  60
   61 KGTKCFICHK ETHGSAKVAS DLQKMLNKRK S

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.69897
Match:	1rmd__
Description:	V(D)J recombination activating protein 1 (RAG1), dimerization domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [186-259]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAVTLDLEKI PFKCTLCKED YKSPVVTNCG HYFCGSCFAK DMKKGTKCFI CHKETHGSAK  60
   61 VASDLQKMLN KRKS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.30103
Match:	1rmdA
Description:	RAG1 DIMERIZATION DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
	4.77196423114965	bayes_pls_golite062009
RNA binding	2.35680777511144	bayes_pls_golite062009
binding	2.19426901055464	bayes_pls_golite062009
small conjugating protein ligase activity	2.17320579037083	bayes_pls_golite062009
ligase activity	2.11117401820312	bayes_pls_golite062009
ubiquitin-protein ligase activity	2.10698039886692	bayes_pls_golite062009
transcription regulator activity	1.62076236255768	bayes_pls_golite062009
protein binding	1.34794206219054	bayes_pls_golite062009
acid-amino acid ligase activity	1.22312570999194	bayes_pls_golite062009
nucleic acid binding	1.22180889694654	bayes_pls_golite062009
DNA binding	1.00346149950987	bayes_pls_golite062009
transcription factor binding	0.39685947299825	bayes_pls_golite062009
transcription factor activity	0.382098789505496	bayes_pls_golite062009
catalytic activity	0.14112008370434	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: