YRC Public Data Repository - Protein Structure Prediction

Protein:	DP3X_ECOLI, DPO3...
Organism:	Escherichia coli
Length:	643 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DP3X_ECOLI, DPO3....

Description	E-value	Query Range	Subject Range
gi\|56128618, gi\|... - gi\|56414361\|ref\|YP_151436.1\| DNA polymerase III subunits gamma and tau [Salmonella enterica subsp. e... gi\|197363281, gi... - gi\|197363281\|ref\|YP_002142918.1\| DNA polymerase III subunits gamma and tau [Salmonella enterica subs...	461.0	[0..1]	[643..1]
gi\|213865424 - gi\|213865424\|ref\|ZP_03387543.1\| DNA polymerase III subunits gamma and tau [Salmonella enterica subsp... gi\|29142765, gi\|... - gi\|29142765\|ref\|NP_806107.1\| DNA polymerase III subunits gamma and tau [Salmonella enterica subsp. e... gi\|16759463 - gi\|16759463\|ref\|NP_455080.1\| DNA polymerase III subunits gamma and tau [Salmonella enterica subsp. e... gi\|213427143 - gi\|213427143\|ref\|ZP_03359893.1\| DNA polymerase III subunits gamma and tau [Salmonella enterica subsp... gi\|25288577, gi\|... - gi\|25288577\|pir\|\|AG0562 DNA polymerase III chains gamma and tau [imported] - Salmonella enterica sub... gi\|213162890 - gi\|213162890\|ref\|ZP_03348600.1\| DNA polymerase III subunits gamma and tau [Salmonella enterica subsp...	460.0	[0..1]	[643..1]
lcl\|NC_016856.1_... - [gene=dnaX] [protein=DNA polymerase III subunits gamma and tau] [protein_id=YP_005236182.1] [locatio... gi\|195631598, gi... - gi\|195631598\|gb\|EDX50118.1\| DNA polymerase III, tau subunit [Salmonella enterica subsp. enterica ser... gi\|167990471, gi... - gi\|205330903\|gb\|EDZ17667.1\| DNA polymerase III, tau subunit [Salmonella enterica subsp. enterica ser... DPO3X_SALTY, DP3... - DNA polymerase III subunit tau OS=Salmonella typhimurium GN=dnaX PE=3 SV=2, (P74876) DNA polymerase ... DPO3X_SALTY - DNA polymerase III subunit tau OS=Salmonella typhimurium GN=dnaX PE=3 SV=2 DPO3X_SALTY - DNA polymerase III subunit tau OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=dn...	459.0	[0..1]	[643..1]
gi\|187430488, gi... - gi\|75177585\|ref\|ZP_00697666.1\| COG2812: DNA polymerase III, gamma/tau subunits [Shigella boydii BS51...	459.0	[0..1]	[643..1]
gi\|62179095, gi\|... - gi\|62179095\|ref\|YP_215512.1\| DNA polymerase III subunits gamma and tau [Salmonella enterica subsp. e...	458.0	[0..1]	[643..1]
gi\|24050648, gi\|... - gi\|24111853\|ref\|NP_706363.1\| DNA polymerase III subunits gamma and tau [Shigella flexneri 2a str. 30... gi\|110614045, gi... - gi\|110804497\|ref\|YP_688017.1\| DNA polymerase III subunits gamma and tau [Shigella flexneri 5 str. 84... gi\|30061970, gi\|... - gi\|30061970\|ref\|NP_836141.1\| DNA polymerase III subunits gamma and tau [Shigella flexneri 2a str. 24...	457.0	[0..1]	[643..1]
gi\|1527143 - gi\|1527143\|gb\|AAC97559.1\| DNA polymerase III tau subunit [Salmonella typhimurium] gi\|1527143\|gb\|AA... - DNA polymerase III tau subunit [Salmonella typhimurium]	456.0	[0..1]	[643..1]
gi\|73854526, gi\|... - gi\|74311049\|ref\|YP_309468.1\| DNA polymerase III subunits gamma and tau [Shigella sonnei Ss046], gi\|7...	454.0	[0..1]	[643..1]
gi\|26246484, gi\|... - gi\|26246484\|ref\|NP_752523.1\| DNA polymerase III subunits gamma and tau [Escherichia coli CFT073], gi... gi\|218557380, gi... - gi\|218557380\|ref\|YP_002390293.1\| DNA polymerase III subunits gamma and tau [Escherichia coli S88], g... gi\|218425897, gi... - gi\|218688333\|ref\|YP_002396545.1\| DNA polymerase III subunits gamma and tau [Escherichia coli ED1a], ... gi\|227884517, gi... - gi\|227884517\|ref\|ZP_04002322.1\| DNA polymerase III subunits gamma and tau [Escherichia coli 83972], ... gi\|170519320, gi... - gi\|170681602\|ref\|YP_001742614.1\| DNA polymerase III, tau subunit [Escherichia coli SMS-3-5], gi\|1705... gi\|91209543, gi\|... - gi\|91209543\|ref\|YP_539529.1\| DNA polymerase III subunits gamma and tau [Escherichia coli UTI89], gi\|... gi\|117622727, gi... - gi\|117622727\|ref\|YP_851640.1\| DNA polymerase III subunits gamma and tau [Escherichia coli APEC O1], ...	453.0	[0..1]	[643..1]
gi\|168786323, gi... - gi\|189373554\|gb\|EDU91970.1\| DNA polymerase III, tau subunit [Escherichia coli O157:H7 str. EC869], g... gi\|189379409, gi... - gi\|189379409\|gb\|EDU97825.1\| DNA polymerase III, tau subunit [Escherichia coli O157:H7 str. EC508], g... gi\|195936033 - gi\|195936033\|ref\|ZP_03081415.1\| DNA polymerase III subunits gamma and tau [Escherichia coli O157:H7 ... gi\|15829777, gi\|... - gi\|15829777\|ref\|NP_308550.1\| DNA polymerase III subunits gamma and tau [Escherichia coli O157:H7 str... gi\|208725803, gi... - gi\|208806002\|ref\|ZP_03248339.1\| DNA polymerase III, tau subunit [Escherichia coli O157:H7 str. EC420... gi\|168760373, gi... - gi\|189369171\|gb\|EDU87587.1\| DNA polymerase III, tau subunit [Escherichia coli O157:H7 str. EC4501], ... gi\|189362356, gi... - gi\|189362356\|gb\|EDU80775.1\| DNA polymerase III, tau subunit [Escherichia coli O157:H7 str. EC4486], ... gi\|187767563, gi... - gi\|187767563\|gb\|EDU31407.1\| DNA polymerase III, tau subunit [Escherichia coli O157:H7 str. EC4196], ... gi\|168778965, gi... - gi\|189002758\|gb\|EDU71744.1\| DNA polymerase III, tau subunit [Escherichia coli O157:H7 str. EC4076], ... gi\|168747852, gi... - gi\|188017706\|gb\|EDU55828.1\| DNA polymerase III, tau subunit [Escherichia coli O157:H7 str. EC4113], ... gi\|189358057, gi... - gi\|189358057\|gb\|EDU76476.1\| DNA polymerase III, tau subunit [Escherichia coli O157:H7 str. EC4401], ... gi\|15829777, gi\|... - gi\|15829777\|ref\|NP_308550.1\| DNA polymerase III subunits gamma and tau [Escherichia coli O157:H7], g... gi\|25288575, gi\|... - pir\|\|G85544 DNA polymerase III tau and gamma subunits [similarity] - Escherichia coli (strain O157:H... gi\|208815685, gi... - gi\|208815685\|ref\|ZP_03256864.1\| DNA polymerase III, tau subunit [Escherichia coli O157:H7 str. EC404... gi\|15800199, gi\|... - gi\|15800199\|ref\|NP_286211.1\| DNA polymerase III subunits gamma and tau [Escherichia coli O157:H7 EDL... gi\|208737178, gi... - gi\|208822985\|ref\|ZP_03263303.1\| DNA polymerase III, tau subunit [Escherichia coli O157:H7 str. EC404... gi\|209399465, gi... - gi\|209399465\|ref\|YP_002269120.1\| DNA polymerase III, tau subunit [Escherichia coli O157:H7 str. EC41... gi\|217322386, gi... - gi\|217326165\|ref\|ZP_03442249.1\| DNA polymerase III, tau subunit [Escherichia coli O157:H7 str. TW145... gi\|254791653, gi... - gi\|254791653\|ref\|YP_003076490.1\| DNA polymerase III/DNA elongation factor III, tau and gamma subunit...	453.0	[0..1]	[643..1]

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Predicted Domain #1

Region A:
Residues: [1-365]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYQVLARKW RPQTFADVVG QEHVLTALAN GLSLGRIHHA YLFSGTRGVG KTSIARLLAK  60
   61 GLNCETGITA TPCGVCDNCR EIEQGRFVDL IEIDAASRTK VEDTRDLLDN VQYAPARGRF 120
  121 KVYLIDEVHM LSRHSFNALL KTLEEPPEHV KFLLATTDPQ KLPVTILSRC LQFHLKALDV 180
  181 EQIRHQLEHI LNEEHIAHEP RALQLLARAA EGSLRDALSL TDQAIASGDG QVSTQAVSAM 240
  241 LGTLDDDQAL SLVEAMVEAN GERVMALINE AAARGIEWEA LLVEMLGLLH RIAMVQLSPA 300
  301 ALGNDMAAIE LRMRELARTI PPTDIQLYYQ TLLIGRKELP YAPDRRMGVE MTLLRALAFH 360
  361 PRMPL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	82.69897
Match:	1xxiB
Description:	ADP Bound E. coli Clamp Loader Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA clamp loader activity	6.51495346697904	bayes_pls_golite062009
protein-DNA loading ATPase activity	6.40748863504898	bayes_pls_golite062009
DNA helicase activity	2.2817164193758	bayes_pls_golite062009
pyrophosphatase activity	2.23646936731119	bayes_pls_golite062009
ATP-dependent DNA helicase activity	1.88455339138556	bayes_pls_golite062009
helicase activity	1.70242731830224	bayes_pls_golite062009
nucleic acid binding	1.49633029954726	bayes_pls_golite062009
catalytic activity	1.32370671504792	bayes_pls_golite062009
structure-specific DNA binding	1.2539059700735	bayes_pls_golite062009
DNA-dependent ATPase activity	1.2537888487362	bayes_pls_golite062009
binding	1.23424453635646	bayes_pls_golite062009
purine NTP-dependent helicase activity	1.19311444180077	bayes_pls_golite062009
ATP-dependent helicase activity	1.19311444180077	bayes_pls_golite062009
double-stranded DNA binding	1.117585097627	bayes_pls_golite062009
DNA-directed DNA polymerase activity	0.971476020912368	bayes_pls_golite062009
DNA binding	0.967303417236485	bayes_pls_golite062009
DNA polymerase activity	0.928091843881235	bayes_pls_golite062009
transcription regulator activity	0.748437190903548	bayes_pls_golite062009
single-stranded DNA binding	0.568457189190858	bayes_pls_golite062009
protein binding	0.447436715913563	bayes_pls_golite062009
mismatched DNA binding	0.31144582840038	bayes_pls_golite062009
DNA strand annealing activity	0.283577486331079	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.248432446853676	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.217252531553173	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.215962398124297	bayes_pls_golite062009
structural constituent of ribosome	0.089234257580272	bayes_pls_golite062009
ATPase activity	0.0740243885501273	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [366-452]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEPEVPRQSF APVAPTAVMT PTQVPPQPQS APQQAPTVPL PETTSQVLAA RQQLQRVQGA  60
   61 TKAKKSEPAA ATRARPVNNA ALERLAS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.0
Match:	2r9gA
Description:	No description for 2r9gA was found.

Predicted Domain #3

Region A:
Residues: [453-643]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTDRVQARPV PSALEKAPAK KEAYRWKATT PVMQQKEVVA TPKALKKALE HEKTPELAAK  60
   61 LAAEAIERDP WAAQVSQLSL PKLVEQVALN AWKEESDNAV CLHLRSSQRH LNNRGAQQKL 120
  121 AEALSMLKGS TVELTIVEDD NPAVRTPLEW RQAIYEEKLA QARESIIADN NIQTLRRFFD 180
  181 AELDEESIRP I

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.39794
Match:	2ayaA
Description:	No description for 2ayaA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: