| Protein: | lgc-35 |
| Organism: | Caenorhabditis elegans |
| Length: | 515 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lgc-35.
| Description | E-value | Query Range |
Subject Range |
|
|
350.0 | [0..1] | [496..1] |
|
Region A: Residues: [1-373] |
1 11 21 31 41 51
| | | | | |
1 MTSLVSKRME FGKIVLLVLV IMEMVQICSG VRAALRLRKK SNSADDSEDE EMQDEIDNAI 60
61 YDKASIFEQG ETHDFLQFLR SIKYDHRQVP DDGYDGPVHV NVSIVVSNIR SVSEVTMDYS 120
121 IEMFYRESWR DPRLTYSRDK FKNKTEISLH ESYSNYLWHP DTFVPNAISS KNPRRQSITH 180
181 RSLLRLRNNG SILYSRRLSL ILTCGMDLTL FPFDTQLCKM GFESYGYTAD KVKYLWSTGA 240
241 IQSLKLHKIR LPDFQVKEAY VTSRVESYAT GDYSRLYVCF VFNRAAGFCF LQLIIPSTAV 300
301 VITSWVSLWM ENETSFQDMI SIILTITFLL FSYNEVMPRV SYIKAMDVYL GVCFCIVFLS 360
361 LIKLAAVKYM RQR
|
| Detection Method: |  |
| Confidence: | 68.69897 |
| Match: | 2bg9A |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [374-515] |
1 11 21 31 41 51
| | | | | |
1 LLITRDTSIV AAGMLPMLRL VNGIGSPAVN GSEGFTYENP AVKKVSMSPD TFTQVQMETN 60
61 GSMSPVCRQN RAKDNGNVSQ SSNCFEFSPT FMHRFHWITQ MTFFFGFVIF CLFYFLVYPN 120
121 IHTQITDDDC DRQMAEWFAE IH
|
| Detection Method: | |
| Confidence: | 30.69897 |
| Match: | 1oedA |
| Description: | Acetylcholine receptor protein, alpha chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cation channel activity | 11.1823056937132 | bayes_pls_golite062009 |
| ion channel activity | 11.1753684044644 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 11.1208555364265 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 11.0903806681397 | bayes_pls_golite062009 |
| channel activity | 11.0903806681397 | bayes_pls_golite062009 |
| gated channel activity | 11.0397691626728 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 10.9870635461822 | bayes_pls_golite062009 |
| substrate-specific channel activity | 10.9375522860542 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 9.75096408199907 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 9.75096408199907 | bayes_pls_golite062009 |
| ligand-gated channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| acetylcholine binding | 8.89748048814778 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 8.63094174477134 | bayes_pls_golite062009 |
| amine binding | 7.31839282808397 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 7.22265353460749 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 6.7875346065164 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 6.75385972663331 | bayes_pls_golite062009 |
| neurotransmitter binding | 6.11782125343012 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 5.97698567435878 | bayes_pls_golite062009 |
| chloride channel regulator activity | 5.57216711685731 | bayes_pls_golite062009 |
| transmembrane receptor activity | 5.4080353535498 | bayes_pls_golite062009 |
| receptor activity | 5.11329651194787 | bayes_pls_golite062009 |
| transporter activity | 5.11262082564788 | bayes_pls_golite062009 |
| transmembrane transporter activity | 5.03439798256257 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 4.91314874981447 | bayes_pls_golite062009 |
| molecular transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| signal transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 3.09231388867595 | bayes_pls_golite062009 |
| binding | 2.4916526322278 | bayes_pls_golite062009 |
| beta-amyloid binding | 1.58357526631942 | bayes_pls_golite062009 |
| G-protein coupled amine receptor activity | 1.37431949258757 | bayes_pls_golite062009 |
| serotonin binding | 1.33584589886834 | bayes_pls_golite062009 |
| serotonin-activated cation-selective channel activity | 1.31324203158511 | bayes_pls_golite062009 |
| 1.15330735898282 | bayes_pls_golite062009 | |
| channel regulator activity | 1.13923307634251 | bayes_pls_golite062009 |
| toxin binding | 1.03329843925063 | bayes_pls_golite062009 |
| drug binding | 0.64715018605883 | bayes_pls_golite062009 |
| protein binding | 0.406954670483187 | bayes_pls_golite062009 |
| serotonin receptor activity | 0.0879353619248899 | bayes_pls_golite062009 |
