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View Structure Prediction Details

Protein: pph-5
Organism: Caenorhabditis elegans
Length: 496 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pph-5.

Description E-value Query
Range
Subject
Range
gi|24954813, gi|... - gi|28141084|gb|AAO26214.1| type 5 protein serine/threonine phosphatase 55 kDa isoform [Lycopersicon ...
357.0 [0..20] [493..5]

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Predicted Domain #1
Region A:
Residues: [1-496]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAATITDDIV ATVLESIEEK SYEDEKEKAG MIKDEANQFF KDQVYDVAAD LYSVAIEIHP  60
   61 TAVLYGNRAQ AYLKKELYGS ALEDADNAIA IDPSYVKGFY RRATANMALG RFKKALTDYQ 120
  121 AVVKVCPNDK DARAKFDECS KIVRRQKFEA AISTDHDKKT VAETLDINAM AIEDSYDGPR 180
  181 LEDKITKEFV LQLIKTFKNQ QKLHKKYAFK MLLEFYNYVK SLPTMVEITV PTGKKFTICG 240
  241 DVHGQFYDLC NIFEINGYPS ETNPYLFNGD FVDRGSFSVE TIFTMIGFKL LYPNHFFMSR 300
  301 GNHESDVMNK MYGFEGEVKA KYTQQMCDMF TETFCWLPLC HLINEKIFVC HGGLFKEDGV 360
  361 TLEDIRKTDR NRQPPDEGIM CDLLWSDPQP INGRSPSKRG VGCQFGPDVT SKWCETNGIE 420
  421 YVVRSHEVKP EGYEMHHNGQ CFTVFSAPNY CDQMNNKGAF ITITGDNLTP RFTPFDAVPH 480
  481 PKLPPMAYAN SLFGFN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 95.154902
Match: 1wao1
Description: PP5 structure
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoprotein phosphatase activity 11.6417995308386 bayes_pls_golite062009
protein serine/threonine phosphatase activity 10.6440947462013 bayes_pls_golite062009
phosphatase activity 10.5525832502704 bayes_pls_golite062009
phosphoric ester hydrolase activity 10.3702645338723 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 9.02791306892273 bayes_pls_golite062009
calcium-dependent protein serine/threonine phosphatase activity 6.04386346716682 bayes_pls_golite062009
myosin phosphatase activity 5.31703100176823 bayes_pls_golite062009
transcription regulator activity 2.36571535004008 bayes_pls_golite062009
hydrolase activity 2.15398287574737 bayes_pls_golite062009
DNA binding 1.71381351716702 bayes_pls_golite062009
nucleic acid binding 1.62783430593918 bayes_pls_golite062009
structural molecule activity 1.5850868178597 bayes_pls_golite062009
binding 1.44538582463569 bayes_pls_golite062009
catalytic activity 1.39852585255405 bayes_pls_golite062009
protein binding 1.33435965029646 bayes_pls_golite062009
transcription factor activity 1.01338808398786 bayes_pls_golite062009
ligase activity 0.825764637499128 bayes_pls_golite062009
transporter activity 0.72444760979153 bayes_pls_golite062009
kinase activity 0.671153901928902 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.653838048261886 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.574603802558181 bayes_pls_golite062009
transcription factor binding 0.518146612491969 bayes_pls_golite062009
RNA binding 0.497066934302855 bayes_pls_golite062009
procollagen-proline 4-dioxygenase activity 0.482467028485988 bayes_pls_golite062009
procollagen-proline dioxygenase activity 0.482467028485988 bayes_pls_golite062009
peptidyl-proline dioxygenase activity 0.482467028485988 bayes_pls_golite062009
peptidyl-proline 4-dioxygenase activity 0.482467028485988 bayes_pls_golite062009
signal transducer activity 0.474250625448338 bayes_pls_golite062009
molecular transducer activity 0.474250625448338 bayes_pls_golite062009
protein kinase activity 0.375779843321939 bayes_pls_golite062009
transferase activity 0.319184977255763 bayes_pls_golite062009
transcription cofactor activity 0.30464889749774 bayes_pls_golite062009
substrate-specific transporter activity 0.169394141800139 bayes_pls_golite062009
transcription activator activity 0.0593768116971065 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle