| Protein: | ggr-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 473 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ggr-1.
| Description | E-value | Query Range |
Subject Range |
|
|
350.0 | [0..38] | [472..102] |
|
Region A: Residues: [1-341] |
1 11 21 31 41 51
| | | | | |
1 MHSLFLKILI YSLMQCVLGQ AEFWDYDENV TQIEEDFKID DVTRILKRVG NYNRNAYPLL 60
61 DQDLATHVDI QMYIEGMSSF HAQSMDFQVD IYFQEKWVDH RLQHNNTKRI LVKDPKLFGL 120
121 LWHPDLYFAN ARTASFHDVT QPNFLVWIYP NGTVWYDCRI SLTVLCMQDL ARYPLDSQNC 180
181 GLRILSYAYD EEQLIIRWNG GNPVEVNRGI RMPDMHLKHI KFYTKRDKYA TGIWSSAVAE 240
241 FHVDREITHH IIQSYIPTSL IVIISWFSFW LDVEAVPGRV SLSITTLLTL ATQSSAARMA 300
301 LPQASDVKAI DVWMGTCMAF VFSAMIEFTV VNYCVRRKVR T
|
| Detection Method: |  |
| Confidence: | 65.0 |
| Match: | 2bg9E |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [342-473] |
1 11 21 31 41 51
| | | | | |
1 KIKPRGLSEQ VHDMVAQYRE KKDKFNNGNC EISYEMALQP NEDNATVQRN FEKKEVREMN 60
61 QASLFVRRSL LPTSKRKTIE DRINRVEENR KNAQKIDRYS RALFPLAFII FNIFYWIYYL 120
121 KYAGSNSPEL LL
|
| Detection Method: | |
| Confidence: | 35.30103 |
| Match: | 1oedB |
| Description: | Acetylcholine receptor protein, beta chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cation channel activity | 11.1823056937132 | bayes_pls_golite062009 |
| ion channel activity | 11.1753684044644 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 11.1208555364265 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 11.0903806681397 | bayes_pls_golite062009 |
| channel activity | 11.0903806681397 | bayes_pls_golite062009 |
| gated channel activity | 11.0397691626728 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 10.9870635461822 | bayes_pls_golite062009 |
| substrate-specific channel activity | 10.9375522860542 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 9.75096408199907 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 9.75096408199907 | bayes_pls_golite062009 |
| ligand-gated channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 9.34902726749692 | bayes_pls_golite062009 |
| acetylcholine binding | 8.89748048814778 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 8.63094174477134 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 7.22265353460749 | bayes_pls_golite062009 |
| amine binding | 7.07838074088669 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 6.7875346065164 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 6.75385972663331 | bayes_pls_golite062009 |
| neurotransmitter binding | 6.11782125343012 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 5.97698567435878 | bayes_pls_golite062009 |
| chloride channel regulator activity | 5.57216711685731 | bayes_pls_golite062009 |
| transmembrane receptor activity | 5.4080353535498 | bayes_pls_golite062009 |
| receptor activity | 5.11329651194787 | bayes_pls_golite062009 |
| transporter activity | 5.11262082564788 | bayes_pls_golite062009 |
| transmembrane transporter activity | 5.03439798256257 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 4.91314874981447 | bayes_pls_golite062009 |
| molecular transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| signal transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 3.09231388867595 | bayes_pls_golite062009 |
| beta-amyloid binding | 2.86563324406667 | bayes_pls_golite062009 |
| binding | 2.4916526322278 | bayes_pls_golite062009 |
| G-protein coupled amine receptor activity | 1.37431949258757 | bayes_pls_golite062009 |
| serotonin binding | 1.33584589886834 | bayes_pls_golite062009 |
| serotonin-activated cation-selective channel activity | 1.31324203158511 | bayes_pls_golite062009 |
| 1.15330735898282 | bayes_pls_golite062009 | |
| channel regulator activity | 1.13923307634251 | bayes_pls_golite062009 |
| toxin binding | 1.03329843925063 | bayes_pls_golite062009 |
| drug binding | 0.64715018605883 | bayes_pls_golite062009 |
| protein binding | 0.406954670483187 | bayes_pls_golite062009 |
| serotonin receptor activity | 0.0879353619248899 | bayes_pls_golite062009 |
