YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|25287692, gi|...
Organism: Arabidopsis thaliana
Length: 596 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|25287692, gi|....

Description E-value Query
Range
Subject
Range
gi|91806214, gi|... - gi|91806214|gb|ABE65835.1| protein kinase [Arabidopsis thaliana], gi|145360146|ref|NP_179637.2| kina...
459.0 [0..1] [596..1]

Back

Predicted Domain #1
Region A:
Residues: [1-119]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSAKGWFQK RQMRGGSRYK GASGGAGGGG SNGSADEHNV ETDEEAVSNT TKQKVAAAKQ  60
   61 YIENHYKEQM KILQERKERR SMLEQKLADA DVSEEDQNNL LKFLEKKETE YMRLQRHKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 2uvmA
Description: No description for 2uvmA was found.

Predicted functions:

Term Confidence Notes
actin binding 4.76659069034376 bayes_pls_golite062009
cytoskeletal protein binding 3.48744511411671 bayes_pls_golite062009
binding 3.29080729281876 bayes_pls_golite062009
protein binding 3.17213698546013 bayes_pls_golite062009
structural molecule activity 3.03944420709983 bayes_pls_golite062009
actin filament binding 2.99963220150463 bayes_pls_golite062009
insulin receptor binding 2.87341016128079 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.12439934882382 bayes_pls_golite062009
transcription regulator activity 2.10584700564436 bayes_pls_golite062009
phosphoinositide 3-kinase binding 1.87491821448967 bayes_pls_golite062009
DNA binding 1.77960272183811 bayes_pls_golite062009
GTPase regulator activity 1.66986263418539 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 1.64990514605397 bayes_pls_golite062009
molecular transducer activity 1.55319485371003 bayes_pls_golite062009
signal transducer activity 1.55319485371003 bayes_pls_golite062009
nucleic acid binding 1.55295906221034 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.53043443218632 bayes_pls_golite062009
kinase activity 1.49733072352288 bayes_pls_golite062009
SH2 domain binding 1.41526564231882 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.36365892826676 bayes_pls_golite062009
protein kinase activity 1.34246406302496 bayes_pls_golite062009
transporter activity 1.28986800087234 bayes_pls_golite062009
small GTPase regulator activity 1.2550809703725 bayes_pls_golite062009
enzyme regulator activity 1.25381967078645 bayes_pls_golite062009
insulin-like growth factor receptor binding 1.19081327922916 bayes_pls_golite062009
receptor activity 1.1755016270537 bayes_pls_golite062009
enzyme binding 1.17212675145623 bayes_pls_golite062009
transmembrane receptor activity 1.1152029796159 bayes_pls_golite062009
phospholipid binding 1.09683218092034 bayes_pls_golite062009
Ran GTPase binding 1.07023555877478 bayes_pls_golite062009
transferase activity 1.05502123133116 bayes_pls_golite062009
receptor binding 1.00859318603128 bayes_pls_golite062009
receptor signaling protein activity 1.00400540041137 bayes_pls_golite062009
oxidoreductase activity 0.965872107791437 bayes_pls_golite062009
kinase binding 0.961706066143 bayes_pls_golite062009
profilin binding 0.91195854193678 bayes_pls_golite062009
protein domain specific binding 0.90578029954417 bayes_pls_golite062009
small GTPase binding 0.8507658747425 bayes_pls_golite062009
GTPase binding 0.82889812790119 bayes_pls_golite062009
substrate-specific transporter activity 0.79883446648737 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.745321902095093 bayes_pls_golite062009
phosphoinositide binding 0.71817045430443 bayes_pls_golite062009
protein kinase binding 0.67284191028382 bayes_pls_golite062009
protein serine/threonine kinase activity 0.611829373978789 bayes_pls_golite062009
protein complex binding 0.55916857709427 bayes_pls_golite062009
structural constituent of cytoskeleton 0.35466574267734 bayes_pls_golite062009
beta-amyloid binding 0.32493221701287 bayes_pls_golite062009
RNA binding 0.324381862881119 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase signaling protein activity 0.28468123649303 bayes_pls_golite062009
structural constituent of muscle 0.276130226777911 bayes_pls_golite062009
G-protein-coupled receptor binding 0.12466518799375 bayes_pls_golite062009
alpha-catenin binding 0.102004310679969 bayes_pls_golite062009
pyrophosphatase activity 0.0611639610381174 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0524559849408587 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0498422520006935 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [120-430]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVADFDLLTM IGKGAFGEVR VCREKTTGQV YAMKKLKKAE MLRRGQVEHV RAERNLLAEV  60
   61 DSNYIVKLYC SFQDDDHLYL VMEYLPGGDM MTLLMRKDTL TEEEAKFYVA ETVLAIESIH 120
  121 RHNYIHRDIK PDNLLLDRYG HLRLSDFGLC KPLDCSAIGE NDFSNNSNGS TEQEAGSTAP 180
  181 KRTQQEQLEH WQRNRRTLAY STVGTPDYIA PEVLLKKGYG MECDWWSLGA IMYEMLVGYP 240
  241 PFYSDDPMST CRKIVNWKSH LKFPEEAILS REAKDLINSL LCSVRRRLGS KGADELKAHT 300
  301 WFETVDWDTI F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.0
Match: 2f57A
Description: Crystal Structure Of The Human P21-Activated Kinase 5
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [431-494]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DMDAAFVPEV NDDLDTQNFE KFDESESETQ TSSKSGPWRK MLSSKDINFV GYTYKNFEIV  60
   61 NDYQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 83.0
Match: 2esmA
Description: Crystal Structure of ROCK 1 bound to fasudil
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [495-596]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPGMGTHLLD HCGVEEEEKV DATNGQVTLR YPTTSFTGPK FGYFHVNLEY NGSSETSDSS  60
   61 ETTSRPPCDR PPPAPPVVQG SFLKLLPPEL EVRPKQEGSE AC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle