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View Structure Prediction Details

Protein: HSD1B_ARATH, HSD...
Organism: Arabidopsis thaliana
Length: 349 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HSD1B_ARATH, HSD....

Description E-value Query
Range
Subject
Range
gi|115250215, gi... - gi|126698778|ref|YP_001087675.1| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile 6...
gi|255306086 - gi|255306086|ref|ZP_05350258.1| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile AT...
gi|255100197 - gi|255100197|ref|ZP_05329174.1| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC...
274.0 [0..43] [296..2]

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Predicted Domain #1
Region A:
Residues: [1-349]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELINDFLNL TAPFFTFFGL CFFLPPFYFF KFLQSIFSTI FSENLYGKVV LITGASSGIG  60
   61 EQLAYEYACR GACLALTARR KNRLEEVAEI ARELGSPNVV TVHADVSKPD DCRRIVDDTI 120
  121 THFGRLDHLV NNAGMTQISM FENIEDITRT KAVLDTNFWG SVYTTRAALP YLRQSNGKIV 180
  181 AMSSSAAWLT APRMSFYNAS KAALLSFFET MRIELGGDVH ITIVTPGYIE SELTQGKYFS 240
  241 GEGELIVNQD MRDVQVGPFP VASASGCAKS IVNGVCRKQR YVTEPSWFKV TYLWKVLCPE 300
  301 LIEWGCRLLY MTGTGMSEDT ALNKRIMDIP GVRSTLYPES IRTPEIKSD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.69897
Match: 1yxmA
Description: Crystal structure of peroxisomal trans 2-enoyl CoA reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
steroid dehydrogenase activity 3.70115036051018 bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3.56748749904419 bayes_pls_golite062009
retinoid binding 3.31525332106318 bayes_pls_golite062009
isoprenoid binding 3.1968520076804 bayes_pls_golite062009
retinol dehydrogenase activity 3.08644105481774 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 2.94416173750168 bayes_pls_golite062009
11-beta-hydroxysteroid dehydrogenase activity 2.8067651687144 bayes_pls_golite062009
structural molecule activity 2.31813292180084 bayes_pls_golite062009
3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity 1.80383455383329 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
DNA binding 1.76363334651124 bayes_pls_golite062009
transcription regulator activity 1.70071720869899 bayes_pls_golite062009
nucleic acid binding 1.58440778443922 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 1.25716430119828 bayes_pls_golite062009
fatty acid synthase activity 1.23679054027553 bayes_pls_golite062009
transcription factor activity 1.00440715995478 bayes_pls_golite062009
binding 0.982999356179965 bayes_pls_golite062009
oxidoreductase activity 0.9367410227151 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.905392379451071 bayes_pls_golite062009
electron carrier activity 0.851536992751213 bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent 0.839863523675468 bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity 0.604742541607263 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 0.57130372652719 bayes_pls_golite062009
ethanol binding 0.43110794057174 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 0.418775403210681 bayes_pls_golite062009
C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity 0.408483170177369 bayes_pls_golite062009
retinol binding 0.40116957175133 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.331998750763528 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.32207755075663 bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity 0.27189038644972 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.261132005311306 bayes_pls_golite062009
cation transmembrane transporter activity 0.200409117794759 bayes_pls_golite062009
ion transmembrane transporter activity 0.0361234153211201 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle