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View Structure Prediction Details

Protein: PNSL5_ARATH
Organism: Arabidopsis thaliana
Length: 259 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PNSL5_ARATH.

Description E-value Query
Range
Subject
Range
gi|21593963 - gi|21593963|gb|AAM65904.1| peptidylprolyl isomerase-like protein [Arabidopsis thaliana]
321.0 [0..1] [259..1]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATLSMTLSN PKSLSAPPRR LSPINTSAFT STSFRLRTKS SFDSISFSSS TPFSASSLLL  60
   61 HTSYTKRNHR CFSVQSNAEV VTEPQS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.715 d.1.1 Microbial ribonucleases
View Download 0.655 d.15.7 Immunoglobulin-binding domains
View Download 0.624 b.1.1 Immunoglobulin
View Download 0.576 d.200.1 Integrin beta tail domain
View Download 0.555 d.17.1 Cystatin/monellin

Predicted Domain #2
Region A:
Residues: [87-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KITHKVYFDI SVGNPVGKLA GRIVIGLYGD DVPQTVENFR ALCTGEKGFG YKGSTFHRVI  60
   61 RDFMIQGGDF EKGNGTGGKS VYGRTFKDEN FKLSHVGPGV LSMANAGPNT NGSQFFICTI 120
  121 KTSWLDGRHV VFGQVIEGME VVKLIEEQET DRGDRPRKKV VIADCGQLPM SEA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 70.221849
Match: 1awqA
Description: Cyclophilin (eukaryotic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein deacetylase activity 4.3775483906311 bayes_pls_golite062009
histone deacetylase activity 4.29026678196473 bayes_pls_golite062009
peptidyl-prolyl cis-trans isomerase activity 3.73853378771688 bayes_pls_golite062009
cis-trans isomerase activity 3.66963215732405 bayes_pls_golite062009
deacetylase activity 3.49940864924766 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3.01511519120932 bayes_pls_golite062009
RNA binding 2.94609837984526 bayes_pls_golite062009
isomerase activity 1.96529188741504 bayes_pls_golite062009
binding 1.46018233647024 bayes_pls_golite062009
mRNA binding 1.45537055700871 bayes_pls_golite062009
unfolded protein binding 1.38124355054041 bayes_pls_golite062009
nucleic acid binding 0.939772862764466 bayes_pls_golite062009
catalytic activity 0.748655649755714 bayes_pls_golite062009
hydrolase activity 0.493806105600863 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.408539130322443 bayes_pls_golite062009
drug binding 0.36339132904137 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.322244688184474 bayes_pls_golite062009
small conjugating protein ligase activity 0.286133802341887 bayes_pls_golite062009
histone binding 0.268719695649015 bayes_pls_golite062009
protein binding 0.130251391659493 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle