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View Structure Prediction Details

Protein: CE35629
Organism: Caenorhabditis elegans
Length: 492 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE35629.

Description E-value Query
Range
Subject
Range
gi|50758260 - gi|50758260|ref|XP_415836.1| PREDICTED: similar to carboxypeptidase D [Gallus gallus]
323.0 [0..52] [489..477]

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Predicted Domain #1
Region A:
Residues: [1-432]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPILLVFLF SALSQCSRLA EEEEQMLIRH FTKEGEVSTM DQLRDTIGPF RDPLNFSHMN  60
   61 YSTLTDHIHN LHRKFPNLTH IYSAGQSVQG RELWVLVVSR YPIEHRKLIP EFKYVANMHG 120
  121 NEVTGRVFLV SLAHTLLENY NSNLWIRQLV DSTRIHLMPS MNPDGYEHAS EGDQAGVTGR 180
  181 QNANGKDLNR NFPSRFPNYF PTSEIQPETI AIMNWTRQIP FALSANLHGG TTLVNYPFDD 240
  241 FPTRTRQSHY APSPDNALFV RLAYTYARGH ERMWKKGPRC LDDDLNISVD PQNGIINGAD 300
  301 WYIVSGGMQD WNYLNTNCFE VTVEMNCEKF PQTKKLRYLW EENKYALLKF IDLIHGAIHG 360
  361 LVIDADTGEG IVNATVSIDE RAKIVVSYGE GEFWRLANMG KYDLTFDHSD YYPVTQTVHV 420
  421 TPQDRSPYIE VR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.69897
Match: 1h8lA
Description: Carboxypeptidase D, a regulatory domain; Carboxypeptidase D, catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.786910294594 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.40766568731738 bayes_pls_golite062009
exopeptidase activity 3.28577934113028 bayes_pls_golite062009
hydrolase activity 2.98013991489506 bayes_pls_golite062009
metallopeptidase activity 2.76103081380105 bayes_pls_golite062009
carboxypeptidase activity 2.63658263814587 bayes_pls_golite062009
metalloexopeptidase activity 1.76058821499096 bayes_pls_golite062009
metallocarboxypeptidase activity 1.56827526553175 bayes_pls_golite062009
catalytic activity 1.3989281287879 bayes_pls_golite062009
endopeptidase activity 0.910234727191613 bayes_pls_golite062009
serine hydrolase activity 0.596149133958797 bayes_pls_golite062009
serine-type peptidase activity 0.578572340123331 bayes_pls_golite062009
binding 0.490423788476091 bayes_pls_golite062009
aminopeptidase activity 0.367803720367061 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [433-492]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQRIIPRSRP VLIPTKSVPN KDEYNVDNSN NKDLRIVTMS SSVCHFSVFM IILSLASLFL  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle