| Protein: | lgc-4 |
| Organism: | Caenorhabditis elegans |
| Length: | 615 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lgc-4.
| Description | E-value | Query Range |
Subject Range |
|
|
419.0 | [0..56] | [554..62] |
|
Region A: Residues: [1-85] |
1 11 21 31 41 51
| | | | | |
1 MIICYSCLTV SILLTIKFVP CRFAGIEHQN TKSRVHFSLL DSRQENDTNH FEIAEAKFQK 60
61 PHNEENTIGT ITKFAPSVQE QHSSA
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [86-417] |
1 11 21 31 41 51
| | | | | |
1 VIPMPHFDQN RLEQALRIKG SIDGTEEALY RSLLDHTVYE KDVRPCIHHS QPTNVTFGFL 60
61 LNQIVEMDER NQALTTRSWL NINWMDPRLS WNESLWSEIK AIYIPHARIW KPDIILVNNA 120
121 IREYYASLVS TDVMVTSDGN VTWLFSALFR SSCPIRVRYY PFDDQQCDLK FASWSHDITE 180
181 INLGLNTDKG DLSSYMNNSE FDLVDMTAVR EVVTFPSDTN SDWPIIVIRI HMHRRPLFYV 240
241 FNHIVPCVLI SSMAVLGFLM PPETGEKINM IITTLLSMGV YLQSITESIP PTSEGVPLIG 300
301 MYYVSSLLMV CLATCVNVIT LNMHRNGAAN QG
|
| Detection Method: | |
| Confidence: | 83.0 |
| Match: | 2bg9A |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [418-554] |
1 11 21 31 41 51
| | | | | |
1 RHVPAWMQKW ILGYLATFMR MSIREPDSIA LLKASQSKKS TIRRSSILRD LKRVKNMSNV 60
61 RAKSKEQNAN RECECMDPLV HIYAESIMSC LAADTKPMNG STIREDFASE STFLGRVVSD 120
121 GIMPRISASS NSVLTEF
|
| Detection Method: | |
| Confidence: | 41.69897 |
| Match: | 1oedB |
| Description: | Acetylcholine receptor protein, beta chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| extracellular ligand-gated ion channel activity | 10.1234885291809 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 10.1234885291809 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 10.0780542200909 | bayes_pls_golite062009 |
| cation channel activity | 8.5858052761298 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 8.57620608456081 | bayes_pls_golite062009 |
| channel activity | 8.57620608456081 | bayes_pls_golite062009 |
| ion channel activity | 8.50385648276422 | bayes_pls_golite062009 |
| gated channel activity | 8.45472729106126 | bayes_pls_golite062009 |
| substrate-specific channel activity | 8.38189052202481 | bayes_pls_golite062009 |
| acetylcholine binding | 8.16606736207577 | bayes_pls_golite062009 |
| ligand-gated channel activity | 8.02211931922735 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 8.02211931922735 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 7.93415141778179 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 7.84962233148559 | bayes_pls_golite062009 |
| amine binding | 6.94698730333481 | bayes_pls_golite062009 |
| chloride channel regulator activity | 4.09042405830166 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.69657181531883 | bayes_pls_golite062009 |
| neurotransmitter binding | 3.68012973608441 | bayes_pls_golite062009 |
| receptor activity | 3.60196173798811 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 3.53144805298686 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 3.03819521978304 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.99543590661304 | bayes_pls_golite062009 |
| molecular transducer activity | 2.5795406626011 | bayes_pls_golite062009 |
| signal transducer activity | 2.5795406626011 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.38330137522171 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.33346254375562 | bayes_pls_golite062009 |
| beta-amyloid binding | 2.17121190042039 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.87616162898157 | bayes_pls_golite062009 |
| transporter activity | 1.81491862158336 | bayes_pls_golite062009 |
| binding | 1.72719973055207 | bayes_pls_golite062009 |
| drug binding | 1.40945164171836 | bayes_pls_golite062009 |
| protein binding | 0.154593355721805 | bayes_pls_golite062009 |
|
Region A: Residues: [555-615] |
1 11 21 31 41 51
| | | | | |
1 ETRFRRILKR VYRSLQQHEI REEILDERSR IQCSGNNLHL SLIDFYYVFF ALQHCSQSSA 60
61 S
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
