| Protein: | gab-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 550 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gab-1.
| Description | E-value | Query Range |
Subject Range |
|
|
348.0 | [0..51] | [549..102] |
|
Region A: Residues: [1-359] |
1 11 21 31 41 51
| | | | | |
1 MRRSKTRRIF HVSITLLLVS TIFCQNGTKP HNNSTSDQMS SSWSNRSQTM YSNASSLLSD 60
61 LLLDYDIRLR PGFGGDALLL TMDIIIASFD SISEVDMDYT LTMYLHQYWT DERLRWSNEI 120
121 PIDEMTLSGE FSQNIWVPDT FLANDKHSYL HEVTERNKML RINVDGKVAY GMRLTSTLSC 180
181 SMNLRNFPLD SQNCTVEIES YGYTTSEVLM KWNYPLAVHG VEQADVPQFT ITGFHTEDSI 240
241 VSTATGSYQR LSLVFQLRRS VGYFIFQTYL PCVLIVMLSW VSFWINHEAT SARVALGITT 300
301 VLTMTTISTG VRQSLPRISY VKSIDIYLVM CFVFVFAALL EYAAVNYSYW GRERGKGGG
|
| Detection Method: |  |
| Confidence: | 65.0 |
| Match: | 2bg9E |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [360-550] |
1 11 21 31 41 51
| | | | | |
1 GNEWPVNGAN KEDRESAVNV QKWVPSGLMD GVPQPQDRRV EALEEAMSTS NTAAQNNNFE 60
61 STSKPKKRSS SPIPPLCRAG NTISEESESP DYPRYSTTSL KGARPHASLN HKTHHLKGRS 120
121 SARAKRRMTL ARMNVSMKQS ISGIGRRARK VIPTIRVRDV NLIDKYSRVV FPVCFIVFNL 180
181 FYWSYYMMVP S
|
| Detection Method: | |
| Confidence: | 28.39794 |
| Match: | 1oedE |
| Description: | Acetylcholine receptor protein, gamma chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nicotinic acetylcholine-activated cation-selective channel activity | 8.81308536112942 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 7.54118453174502 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 7.54118453174502 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 7.22265353460749 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 7.15153709132033 | bayes_pls_golite062009 |
| channel activity | 7.15153709132033 | bayes_pls_golite062009 |
| ion channel activity | 7.1489450300492 | bayes_pls_golite062009 |
| gated channel activity | 7.07040350691167 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 7.06843378380114 | bayes_pls_golite062009 |
| cation channel activity | 7.05528966701307 | bayes_pls_golite062009 |
| substrate-specific channel activity | 7.02602175506525 | bayes_pls_golite062009 |
| acetylcholine binding | 6.82207267193568 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 6.7875346065164 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 6.75385972663331 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 6.5970757722697 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 6.32442846604167 | bayes_pls_golite062009 |
| ligand-gated channel activity | 6.32442846604167 | bayes_pls_golite062009 |
| neurotransmitter binding | 6.11782125343012 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 5.97698567435878 | bayes_pls_golite062009 |
| amine binding | 5.5479469647168 | bayes_pls_golite062009 |
| transmembrane receptor activity | 5.4080353535498 | bayes_pls_golite062009 |
| receptor activity | 5.11329651194787 | bayes_pls_golite062009 |
| transporter activity | 5.11262082564788 | bayes_pls_golite062009 |
| transmembrane transporter activity | 5.03439798256257 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 4.91314874981447 | bayes_pls_golite062009 |
| molecular transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| signal transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 3.09231388867595 | bayes_pls_golite062009 |
| chloride channel regulator activity | 2.86219582948074 | bayes_pls_golite062009 |
| binding | 2.4916526322278 | bayes_pls_golite062009 |
| G-protein coupled amine receptor activity | 1.37431949258757 | bayes_pls_golite062009 |
| serotonin binding | 1.33584589886834 | bayes_pls_golite062009 |
| serotonin-activated cation-selective channel activity | 1.31324203158511 | bayes_pls_golite062009 |
| 1.15330735898282 | bayes_pls_golite062009 | |
| channel regulator activity | 1.13923307634251 | bayes_pls_golite062009 |
| toxin binding | 0.91098263903324 | bayes_pls_golite062009 |
| drug binding | 0.64715018605883 | bayes_pls_golite062009 |
| beta-amyloid binding | 0.62979601863874 | bayes_pls_golite062009 |
| protein binding | 0.406954670483187 | bayes_pls_golite062009 |
| serotonin receptor activity | 0.0879353619248899 | bayes_pls_golite062009 |
