| Protein: | lgc-50 |
| Organism: | Caenorhabditis elegans |
| Length: | 476 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lgc-50.
| Description | E-value | Query Range |
Subject Range |
|
|
359.0 | [0..12] | [473..101] |
|
Region A: Residues: [1-340] |
1 11 21 31 41 51
| | | | | |
1 MGFFFEYLEF NSRINLGKLI DTLLTDYDTH LLPEAEGVNV TIELHVQGVS GISEITGDFS 60
61 LDVMYSEIWQ DPRLSFKHLN VCATNITLKV SDFRKKIWTP DTCIINSKSS SIHSSPSENT 120
121 FVILYENGLV WSNFRLNVKT PCSVNLKMFP FDSLSCEIVL ESYSFNTDEV RLMWHDVPIT 180
181 MMEKVELPDF DLIGWSTDHQ RLEYPNGIWD RAKVKFTFAR RYGFYLFQSY FPTSLTVISS 240
241 WVGFFFDVRS VSARITLGVS SLLALTFQFG NVLRHLPRVS YIKCLDVWMI FSVIFIFCTL 300
301 VELAIVCQLN RWERERQIGS KVLGHWLNQI RKTRKKESKA
|
| Detection Method: |  |
| Confidence: | 68.69897 |
| Match: | 2bg9A |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [341-476] |
1 11 21 31 41 51
| | | | | |
1 DEGGGGGVGG LLRKRIPVLA QLKAAATDSN SGAATAMTTA IQPPNTNLNS ITNSDNSKLV 60
61 ANNFTSIEHE TYAYEKKRGF SHCFQRFVYA ICPPDRDWTI TSVQVDRCSM IMFPLSFLIF 120
121 NVVYWSIYFM KMDRPM
|
| Detection Method: | |
| Confidence: | 33.69897 |
| Match: | 1oedE |
| Description: | Acetylcholine receptor protein, gamma chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nicotinic acetylcholine-activated cation-selective channel activity | 10.5235963668526 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 9.15372508589935 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 9.15372508589935 | bayes_pls_golite062009 |
| acetylcholine binding | 8.38904634571954 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 8.13745808237824 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 7.22265353460749 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 7.15153709132033 | bayes_pls_golite062009 |
| channel activity | 7.15153709132033 | bayes_pls_golite062009 |
| ion channel activity | 7.1489450300492 | bayes_pls_golite062009 |
| amine binding | 7.07838074088669 | bayes_pls_golite062009 |
| gated channel activity | 7.07040350691167 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 7.06843378380114 | bayes_pls_golite062009 |
| cation channel activity | 7.05528966701307 | bayes_pls_golite062009 |
| substrate-specific channel activity | 7.02602175506525 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 6.7875346065164 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 6.75385972663331 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 6.32442846604167 | bayes_pls_golite062009 |
| ligand-gated channel activity | 6.32442846604167 | bayes_pls_golite062009 |
| neurotransmitter binding | 6.11782125343012 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 5.97698567435878 | bayes_pls_golite062009 |
| transmembrane receptor activity | 5.4080353535498 | bayes_pls_golite062009 |
| receptor activity | 5.11329651194787 | bayes_pls_golite062009 |
| transporter activity | 5.11262082564788 | bayes_pls_golite062009 |
| transmembrane transporter activity | 5.03439798256257 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 4.91314874981447 | bayes_pls_golite062009 |
| chloride channel regulator activity | 4.35872903043893 | bayes_pls_golite062009 |
| molecular transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| signal transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 3.09231388867595 | bayes_pls_golite062009 |
| binding | 2.4916526322278 | bayes_pls_golite062009 |
| beta-amyloid binding | 1.6057916207188 | bayes_pls_golite062009 |
| G-protein coupled amine receptor activity | 1.37431949258757 | bayes_pls_golite062009 |
| serotonin binding | 1.33584589886834 | bayes_pls_golite062009 |
| serotonin-activated cation-selective channel activity | 1.31324203158511 | bayes_pls_golite062009 |
| 1.15330735898282 | bayes_pls_golite062009 | |
| channel regulator activity | 1.13923307634251 | bayes_pls_golite062009 |
| toxin binding | 1.03329843925063 | bayes_pls_golite062009 |
| drug binding | 0.64715018605883 | bayes_pls_golite062009 |
| protein binding | 0.406954670483187 | bayes_pls_golite062009 |
| serotonin receptor activity | 0.0879353619248899 | bayes_pls_golite062009 |
