| Protein: | nhr-49 |
| Organism: | Caenorhabditis elegans |
| Length: | 501 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-49.
| Description | E-value | Query Range |
Subject Range |
|
|
324.0 | [0..1] | [423..30] |
|
Region A: Residues: [1-191] |
1 11 21 31 41 51
| | | | | |
1 MDYFLDASKH IQLNQIDEES SDDFMDLVDP LAEPCAVCGD KSTGTHYGVI SCNGCKGFFR 60
61 RTVLRDQKFT CRFNKRCVID KNFRCACRYC RFQKCVQVGM KREAIQFERD PVGSPTSGAS 120
121 LNGTPFKKDR SPGYENGNSN GVGSNGMGQE NMRTVPQSSS VIDALMEMEA RVNQEMCNRY 180
181 RRSQIFANGS G
|
| Detection Method: |  |
| Confidence: | 29.221849 |
| Match: | 2a66A |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [192-501] |
1 11 21 31 41 51
| | | | | |
1 GSNGNDTDIQ QGSDSGASAF APPNRPCTTE VDLNEISRTT LLLMVEWAKT INPFMDLSME 60
61 DKIILLKNYA PQHLILMPAF RSPDTTRVCL FNNTYMTRDN NTDLNGFAAF KTSNITPRVL 120
121 DEIVWPMRQL QMREQEFVCL KALAFLHPEA KGLSNSSQIM IRDARNRVLK ALYAFILDQM 180
181 PDDAPTRYGN ILLLAPALKA LTQLLIENMT LTKFFGLAEV DSLLSEFILD DINDHSTAPV 240
241 SLQQHLSSPT TLPTNGVSPL NPAGSVGSVS SVSGITPTGM LSATLAAPLA IHPLQSQDSI 300
301 LNSEQNNHML
|
| Detection Method: | |
| Confidence: | 51.09691 |
| Match: | 1xdkA |
| Description: | Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 4.81441024181511 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 3.91470119037087 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| hormone receptor binding | 3.79647267365529 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription activator binding | 2.98235973123409 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| receptor activity | 2.62895787183554 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| transcription coactivator activity | 2.27959329058894 | bayes_pls_golite062009 |
| molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| ecdysteroid hormone receptor activity | 1.71585537346083 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| estrogen response element binding | 1.56094639526803 | bayes_pls_golite062009 |
| estrogen receptor activity | 1.47290778095383 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| promoter binding | 1.28787959668198 | bayes_pls_golite062009 |
| palmitoyl-CoA hydrolase activity | 1.00607914318115 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| steroid hormone receptor binding | 0.754240851368212 | bayes_pls_golite062009 |
| retinoic acid binding | 0.676688935879073 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.47826452126899 | bayes_pls_golite062009 |
| lipid binding | 0.475303782949439 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.42652610679613 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
