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View Structure Prediction Details

Protein: CE32274
Organism: Caenorhabditis elegans
Length: 692 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE32274.

Description E-value Query
Range
Subject
Range
gi|37196990, gi|... - gi|37678251|ref|NP_932860.1| Zn-dependent oligopeptidase [Vibrio vulnificus YJ016], gi|37196990|dbj|...
579.0 [0..1] [681..1]

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Predicted Domain #1
Region A:
Residues: [1-692]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRSVILRHS RTISRNSWVA RAFRSEKVDK ETGLFGNKNL KTAESFNELP AAVKKSTDAL  60
   61 IQELLTPSQN PRTSIQIVDD ISNEICKSAD LAECVRQLHS EPEFRNAAED VSRNFCELVE 120
  121 SLNTNTALYQ KLKSSEITES SRLDDVDKRT LTLLLDDFEQ SGVHLKDNQK EQFVQLSSEI 180
  181 FDAGARFQQN CDRIVSVGKF DQAKYGLPSQ IYTPVSNSLD RSKRKMVYNT FYRHDDIQES 240
  241 YLQHLISSRH QLSQLTGFES FAHRAQRNSL LENYDTVRSF LWGVVEKCRG AFEKELAVLI 300
  301 DVSAQCSQQD NNNGNNEIST IAEHDLGFLM HLYRESAYDI AQVSQQSSPF FTFNSIWNGF 360
  361 STLTQRLYGV RLIEEPLISG EMWNSSGVMK LQAVDEQNNE LGVIYVDVSI RPEKAVGDCH 420
  421 YTVRCSKQLS DGTWQMPILV LSLGLVDGHS SQWRNSRVSF HSAETMFHEL GHAMHSILGR 480
  481 TKYQHVAGTR CPQDFSEIPS NLMEYFFSDL GVMTDIIRRT DRPEEQLSIE SAATLLASRH 540
  541 SFTAIETVQQ AAYGLYDLEV HGPIAAPQIA SGRMTTTELF HDIMNKTMPH IQRSPDSAFQ 600
  601 HRFHHTVQYG AKYYSYLVAR ASACLIWQQR FLNDPFSRKW GDCWAEVQSH GGGHHPAVLL 660
  661 EKILGFRPTE NDLTQALSKE SQHLANLDAV TV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 132.0
Match: 1i1iP
Description: Neurolysin (endopeptidase 24.16)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 3.61797750040144 bayes_pls_golite062009
metallopeptidase activity 3.50779710207955 bayes_pls_golite062009
metalloendopeptidase activity 3.48758651243973 bayes_pls_golite062009
endopeptidase activity 3.33212790314223 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.28672457209168 bayes_pls_golite062009
hydrolase activity 2.4180994157249 bayes_pls_golite062009
transporter activity 1.72601293225401 bayes_pls_golite062009
binding 1.55761777216628 bayes_pls_golite062009
transmembrane transporter activity 1.40574642512021 bayes_pls_golite062009
transition metal ion binding 1.38438013458016 bayes_pls_golite062009
ion binding 1.04016734747204 bayes_pls_golite062009
cation binding 0.956500682358628 bayes_pls_golite062009
metal ion binding 0.956500682358628 bayes_pls_golite062009
substrate-specific transporter activity 0.933447696036882 bayes_pls_golite062009
catalytic activity 0.891187593353827 bayes_pls_golite062009
bradykinin receptor binding 0.885174712362249 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.655915544358586 bayes_pls_golite062009
protein binding 0.530727556830171 bayes_pls_golite062009
ion transmembrane transporter activity 0.414956359430633 bayes_pls_golite062009
exopeptidase activity 0.364756038518376 bayes_pls_golite062009
aminopeptidase activity 0.21808506596674 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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