| Protein: | nhr-35 |
| Organism: | Caenorhabditis elegans |
| Length: | 542 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-35.
| Description | E-value | Query Range |
Subject Range |
|
|
343.0 | [0..35] | [542..1] |
|
Region A: Residues: [1-163] |
1 11 21 31 41 51
| | | | | |
1 MGNKIHAGFT FTPSHARSLD CFVCLLVLFS FRSTPPHGRH PAIEPTLLIS HYYRGQMLGT 60
61 YNGDSKAETD GKDNSICHIC SDVATGRHYG AIACNGCKGF FRRTVRRNYE YHCRFESKCE 120
121 IDKHNRAVCR YCRFMKCISS GMRDDQVQSE RDVIGKREKK DNM
|
| Detection Method: |  |
| Confidence: | 29.69897 |
| Match: | 2a66A |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [164-438] |
1 11 21 31 41 51
| | | | | |
1 KTYCQDPTPR TSPELTMSPV EDEYDQLLES LLKSEMTIQS LRDTVITQTG NVEYTTKSKN 60
61 RLSHTDRTAT LNDVLKSMHS QLLLVIEWAK TLPEFKQLSG ADQAVLLKNF AGQHVTLCVA 120
121 YRSVGANDAL KLLNDLYIPR ASKTTPHLKE YVDGFYLRDC EKVMDQLVEP MRFLKLDNKE 180
181 FVALKACVLF NPVAPGLSNH AVNLVLNARR KIFAAFEKYV RVNKPLETTR VGDLTFFILT 240
241 PLSVLSKSIS EDIMFTKVSG VARIDVLMEE LILAE
|
| Detection Method: | |
| Confidence: | 48.522879 |
| Match: | 1lbdA |
| Description: | LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| vitamin D3 receptor activity | 5.5563493713822 | bayes_pls_golite062009 |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| ecdysteroid hormone receptor activity | 5.24236817167929 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 4.81441024181511 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 3.91470119037087 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| hormone receptor binding | 3.79647267365529 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription activator binding | 2.98235973123409 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| receptor activity | 2.62895787183554 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| transcription coactivator activity | 2.27959329058894 | bayes_pls_golite062009 |
| vitamin D binding | 2.05947211013242 | bayes_pls_golite062009 |
| signal transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| molecular transducer activity | 2.04709877069886 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| retinoid binding | 1.57244905045132 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.56146647486761 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.48246587604476 | bayes_pls_golite062009 |
| estrogen receptor activity | 1.47290778095383 | bayes_pls_golite062009 |
| isoprenoid binding | 1.45798199211445 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| juvenile hormone binding | 1.35482717568148 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| promoter binding | 1.28787959668198 | bayes_pls_golite062009 |
| palmitoyl-CoA hydrolase activity | 1.23181585568439 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| hormone binding | 0.895172563790297 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| steroid hormone receptor binding | 0.754240851368212 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| lipid binding | 0.475303782949439 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| receptor binding | 0.418843034756825 | bayes_pls_golite062009 |
| estrogen response element binding | 0.26972535024334 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
|
Region A: Residues: [439-542] |
1 11 21 31 41 51
| | | | | |
1 TDYGEDRQDQ TPCSIMNDTP SGSQDMCSPC PEDLLRTSTS SNSPTNSSLT AGLLLKTDDA 60
61 MMSGIGTQYT TPQPHTPQFA DSSHLNLPYA PFTSSYNQYP NTYS
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
