| Protein: | eat-16 |
| Organism: | Caenorhabditis elegans |
| Length: | 431 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for eat-16.
| Description | E-value | Query Range |
Subject Range |
|
|
432.0 | [0..2] | [412..261] |
|
Region A: Residues: [1-194] |
1 11 21 31 41 51
| | | | | |
1 MMPPLTKIEV LAKRVMEGAQ LKTHKYFRIA VPHAITGQQL IALVLERGAP DDEAEASHLA 60
61 SLLLHHGYMF PVIEHGQPFK DDGTLYRLQR PYFWPSQAEL VPDVEYAIYL NKRLLRNEQK 120
121 HGLEEDEVES FNRLADVLAH MWAFIVQQSE LQLKQQKEKK KVDKVVFDSE ERAFWKIRKP 180
181 SRGGPNFLED PYMK
|
| Detection Method: |  |
| Confidence: | 17.69897 |
| Match: | 2csoA |
| Description: | Solution structure of the DEP domain of human pleckstrin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 3.77201910025409 | bayes_pls_golite062009 |
| binding | 3.52874320222492 | bayes_pls_golite062009 |
| DNA binding | 3.44642410378325 | bayes_pls_golite062009 |
| nucleic acid binding | 3.25777282180864 | bayes_pls_golite062009 |
| transcription factor activity | 2.83460075788873 | bayes_pls_golite062009 |
| transcription repressor activity | 2.26839643623044 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.4788427609721 | bayes_pls_golite062009 |
| transcription activator activity | 1.28486271107855 | bayes_pls_golite062009 |
| signal transducer activity | 0.968719315363638 | bayes_pls_golite062009 |
| molecular transducer activity | 0.968719315363638 | bayes_pls_golite062009 |
| protein binding | 0.753698599635855 | bayes_pls_golite062009 |
| transcription factor binding | 0.63938506997853 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.49916895549368 | bayes_pls_golite062009 |
| receptor binding | 0.0995086620605325 | bayes_pls_golite062009 |
|
Region A: Residues: [195-266] |
1 11 21 31 41 51
| | | | | |
1 IEKKIRRQNA QGYRCLMDRL RFAIKTKPWL KALKASDTMV TWVDQRAEFD PFLHPPQPSN 60
61 PWISDEASFW NQ
|
| Detection Method: | |
| Confidence: | 2.89 |
| Match: | 1xhmB |
| Description: | The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 1.90500749049821 | bayes_pls_golite062009 |
| signal transducer activity | 1.70315911322844 | bayes_pls_golite062009 |
| molecular transducer activity | 1.70315911322844 | bayes_pls_golite062009 |
| GTPase activity | 0.944482131496004 | bayes_pls_golite062009 |
| protein binding | 0.40736300061233 | bayes_pls_golite062009 |
| receptor binding | 0.363468238376214 | bayes_pls_golite062009 |
|
Region A: Residues: [267-431] |
1 11 21 31 41 51
| | | | | |
1 PTDTSSAEIP TEKRVKRWGL SVQELVKDPI GRQVLETFLE SEFSSENIRF WIAIQDLKYA 60
61 PNEQIYQKAE RIREEFLAQG APAQVNVDNR TLDQTLECIS KAKDASQMRF AFYHSEEHVF 120
121 TLMAKDSYPR FVRSQIYKAV LTAAQQHGTK RLGWRNFVFN MGNYV
|
| Detection Method: | |
| Confidence: | 36.69897 |
| Match: | 1fqiA |
| Description: | RGS9, RGS domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.35238988967981 | bayes_pls_golite062009 |
| GTPase regulator activity | 1.92987277493861 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.90800479999702 | bayes_pls_golite062009 |
| GTPase activator activity | 1.87534424848905 | bayes_pls_golite062009 |
| enzyme activator activity | 1.62073651679221 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.49796137854909 | bayes_pls_golite062009 |
| protein binding | 1.34804002381061 | bayes_pls_golite062009 |
| signal transducer activity | 1.14361809679544 | bayes_pls_golite062009 |
| molecular transducer activity | 1.14361809679544 | bayes_pls_golite062009 |
| beta-catenin binding | 0.59248827140739 | bayes_pls_golite062009 |
