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View Structure Prediction Details

Protein: ubc-1
Organism: Caenorhabditis elegans
Length: 192 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ubc-1.

Description E-value Query
Range
Subject
Range
gi|7497060 - gi|7497060|pir||T32959 hypothetical protein C35B1.1 - Caenorhabditis elegans
217.0 [0..1] [192..1]

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Predicted Domain #1
Region A:
Residues: [1-192]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTPSRRRLM RDFKKLQEDP PAGVSGAPTE DNILTWEAII FGPQETPFED GTFKLSLEFT  60
   61 EEYPNKPPTV KFISKMFHPN VYADGSICLD ILQNRWSPTY DVAAILTSIQ SLLDEPNPNS 120
  121 PANSLAAQLY QENRREYEKR VQQIVEQSWL NFGENEGDAV LKDDVEIEEI AAPGANDADD 180
  181 DRMDEGASGS NA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.0
Match: 1q34A
Description: Crystal structures of two UBC (E2) enzymes of the ubiquitin-conjugating system in Caenorhabditis elegans
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 11.3486134076304 bayes_pls_golite062009
small conjugating protein ligase activity 11.2964721480824 bayes_pls_golite062009
acid-amino acid ligase activity 10.2401422444624 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 8.93602533934698 bayes_pls_golite062009
HLH domain binding 8.10904818707269 bayes_pls_golite062009
ligase activity 5.89730943108033 bayes_pls_golite062009
SUMO ligase activity 3.88357560284404 bayes_pls_golite062009
ISG15 ligase activity 3.37361650623694 bayes_pls_golite062009
NEDD8 ligase activity 3.30521803258995 bayes_pls_golite062009
transcription regulator activity 2.21355731489173 bayes_pls_golite062009
nucleic acid binding 2.13970605403492 bayes_pls_golite062009
DNA binding 1.95596447916631 bayes_pls_golite062009
protein binding 1.77678273247394 bayes_pls_golite062009
binding 1.75350658654805 bayes_pls_golite062009
transcription repressor activity 1.5236035191291 bayes_pls_golite062009
transcription activator activity 1.19240180311941 bayes_pls_golite062009
catalytic activity 0.891402822028799 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.58835335751383 bayes_pls_golite062009
kinase activity 0.519703305315987 bayes_pls_golite062009
protein kinase activity 0.443948654247666 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.373779304908933 bayes_pls_golite062009
small protein activating enzyme activity 0.36227294335656 bayes_pls_golite062009
protein serine/threonine kinase activity 0.182854082413338 bayes_pls_golite062009
transcription corepressor activity 0.122859425935324 bayes_pls_golite062009
transferase activity 0.0984525836903841 bayes_pls_golite062009
transcription factor binding 0.0104967529560147 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle