| Protein: | unc-103 |
| Organism: | Caenorhabditis elegans |
| Length: | 791 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-103.
| Description | E-value | Query Range |
Subject Range |
|
|
466.0 | [0..3] | [781..266] |
|
Region A: Residues: [1-364] |
1 11 21 31 41 51
| | | | | |
1 MSSSTNHTGI IQHHPSQSQQ QATTSSGAGN AVASQAKQLM VVLQSGSYKV LSLGADVLPE 60
61 YKLQPTRIHH CTIVHYSPFK AVWDWIILLL VIYTAVFTPY VAAFLLRELQ DTAKKSRFTE 120
121 PLEIVDLIVD IMFIVDIIIN FRTTYVNEND EACQVVSDPG KIATHYFKGW FIIDMVAAVP 180
181 FDLLLVSTNS DETTTLIGLL KTARLLRLVR VARKLDRYSE YGAAVLLLLM ATFALIAHWL 240
241 ACIWYAIGSA ELSHKEYTWL HQLSKQLAQP YTSTNGTIPT GGPTLKSRYV TSLYFTLSTI 300
301 TSIGFGNVSA TTDSEKIFTI IMMILGSLMY ASVFGNVSAI IQRLYSGTAR YHTEMSRLRE 360
361 FIRF
|
| Detection Method: |  |
| Confidence: | 42.045757 |
| Match: | 2a79B |
| Description: | Mammalian Shaker Kv1.2 potassium channel- beta subunit complex |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [365-608] |
1 11 21 31 41 51
| | | | | |
1 HQIPNPLRQR LEEYFQHAWS YTNGIDMNLV LKGFPDCLQA DICLHLNRNL LSGCAAFAGS 60
61 TPGCLRALSM RFRTTHSPPG DTLVHRGDIL TGLYFIARGS VEILNDDNTV MGILGKDDIF 120
121 GENPLLYDEV GKSSCNVRAL TYCDLHKILR DDLLDVLDMY PEFAETFCKN LTITYNLRDD 180
181 AQSLRKKFDR HKLLRMSSSM NKDRYTTPPD GDHGNAAVRR SAESVSRCDS NPIDRRQSAG 240
241 SRSS
|
| Detection Method: | |
| Confidence: | 29.045757 |
| Match: | 1q3eA |
| Description: | HCN2J 443-645 in the presence of cGMP |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| intracellular cyclic nucleotide activated cation channel activity | 11.4016635726548 | bayes_pls_golite062009 |
| cyclic nucleotide-gated ion channel activity | 11.4016635726548 | bayes_pls_golite062009 |
| intracellular cGMP activated cation channel activity | 9.19973076787954 | bayes_pls_golite062009 |
| ion channel activity | 8.54258173089828 | bayes_pls_golite062009 |
| gated channel activity | 8.40583491856766 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 8.39905773163311 | bayes_pls_golite062009 |
| channel activity | 8.39905773163311 | bayes_pls_golite062009 |
| substrate-specific channel activity | 8.39470084162975 | bayes_pls_golite062009 |
| cation channel activity | 8.37340171056317 | bayes_pls_golite062009 |
| cGMP binding | 7.7575871125398 | bayes_pls_golite062009 |
| intracellular ligand-gated ion channel activity | 7.52815183034083 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 7.41584542512987 | bayes_pls_golite062009 |
| ligand-gated channel activity | 7.41584542512987 | bayes_pls_golite062009 |
| cyclic nucleotide binding | 7.37322432929433 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 7.07543487134503 | bayes_pls_golite062009 |
| GMP binding | 5.49455172024846 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 4.92543918512794 | bayes_pls_golite062009 |
| voltage-gated channel activity | 4.90247452112447 | bayes_pls_golite062009 |
| intracellular cAMP activated cation channel activity | 3.68461701924174 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 3.17407714154852 | bayes_pls_golite062009 |
| potassium channel activity | 3.16645830461177 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 2.42821009576643 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.37087453697521 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.11234289483733 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.00131870009595 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.99073791328042 | bayes_pls_golite062009 |
| binding | 1.39247933044015 | bayes_pls_golite062009 |
| signal transducer activity | 0.758143612871078 | bayes_pls_golite062009 |
| molecular transducer activity | 0.758143612871078 | bayes_pls_golite062009 |
| protein binding | 0.71319432010926 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.362412435891451 | bayes_pls_golite062009 |
|
Region A: Residues: [609-791] |
1 11 21 31 41 51
| | | | | |
1 SRCSPPHAAL TATRSEATPL LRRSTNHHEE DDALFDDIRA FARGNTVTMS PTVAGNSVSP 60
61 TTAIHNDGIH SQQLSDRSDD YEERRANMFG RRLESIESQM ERMQNKFNSD METLIKLVKE 120
121 QSIIRNNGSS NEEPNARYRP NNYISSAIRL PNGGGGGVVD EMRVSRLSSH EPPTPTQETD 180
181 TIL
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
