| Protein: | vps-34 |
| Organism: | Caenorhabditis elegans |
| Length: | 650 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for vps-34.
| Description | E-value | Query Range |
Subject Range |
|
|
534.0 | [0..1] | [650..252] |
|
Region A: Residues: [1-650] |
1 11 21 31 41 51
| | | | | |
1 MRVSTSVNGG VGIVSACTRY CVADPELLLE SLAEVKHSAM TRRIRDVEDE RHRQVKPNKQ 60
61 AKDRLETIVN LPSSQVLTRE QRDLVWKFRH YLRQFPKALN KYLRSVNWVH PQEVKTALAL 120
121 MNDWELIEAE DALELLSSAF THPAVRAYSV SRLLEAASPE QVLLYLPQLV QALKYEQGQQ 180
181 LPEEGNPVPV VSEEEGKIPS VATTPTEELE GRDMTVVTKK EARKAASGDL ATFLIDYALA 240
241 SPKVSNYLYW HLKTEIESTK ESKEEHSKMY QNIQDRLMEA LVKRPDTRAQ VDSLHQQQIF 300
301 VEDLIILMNE AKARGGRLNE SKSAEFRTML SRAKHMLDLK GVHLPLDPSF RLSSVIPDTA 360
361 SFFKSEMMPA KISFKVLQPN GKADRNIPEE YTVIFKTGDD LRQDQLIQQM VRLIDIILKK 420
421 GQLDLKLTPY LVLSTGVGQG FVQCIKSKPL RAIQEQYKAH KMDCIREAMK ELRPGDGPFG 480
481 IEPNVIDNYV RSLAGYSVIM YILGLGDRHL DNLLLCENGK LFHVDFGFIL GRDPKPMPPP 540
541 MKLTSEMVQV MGGVKSKQFL EFVQHVDSAY RILRRHSNVL LNLFSLMLDA GIPDIAAEPD 600
601 KAIFKIEQRL RLDLSDEAAT KHIFTQIESS LNAKMAMISD IIHAYKQNLM
|
| Detection Method: |  |
| Confidence: | 120.0 |
| Match: | 1e7uA |
| Description: | Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| protein kinase activity | 5.17195961442593 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| 1-phosphatidylinositol-3-kinase activity | 3.36507457832455 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase activity | 3.35431422298319 | bayes_pls_golite062009 |
| lipid kinase activity | 3.32869674544617 | bayes_pls_golite062009 |
| inositol or phosphatidylinositol kinase activity | 3.07779388034304 | bayes_pls_golite062009 |
| binding | 2.31930216202447 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| molecular transducer activity | 1.79921740914853 | bayes_pls_golite062009 |
| signal transducer activity | 1.79921740914853 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 1.3898059094397 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.38496328649031 | bayes_pls_golite062009 |
| receptor signaling protein activity | 1.27291233344322 | bayes_pls_golite062009 |
| protein binding | 1.22565748038754 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| profilin binding | 0.635898406235221 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.58590430118616 | bayes_pls_golite062009 |
| MAP kinase activity | 0.5066845540941 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| phospholipid binding | 0.304184566966103 | bayes_pls_golite062009 |
| phosphatidylinositol-4,5-bisphosphate 3-kinase activity | 0.147483323744488 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.0556163711947139 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.00652065412910241 | bayes_pls_golite062009 |
