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View Structure Prediction Details

Protein: cyn-3
Organism: Caenorhabditis elegans
Length: 173 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cyn-3.

Description E-value Query
Range
Subject
Range
gi|50301248 - gi|50301248|gb|AAT73777.1| TRIM5/cyclophilin A fusion protein [Aotus trivirgatus]
271.0 [0..1] [171..311]
gi|11270316, gi|... - gi|1563719|emb|CAA69622.1| cyclophylin [Digitalis lanata], pir||T50768 peptidylprolyl isomerase (EC ...
264.0 [0..1] [171..1]
PPID_NEUCR - 41 kDa peptidyl-prolyl cis-trans isomerase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CB...
PPID_NEUCR - 41 kDa peptidyl-prolyl cis-trans isomerase OS=Neurospora crassa GN=cyp-41 PE=2 SV=1
262.0 [0..2] [171..10]
gi|37003448 - gi|37003448|gb|AAQ87931.1| Bet v 7-like protein [Cochliobolus lunatus]
261.0 [0..1] [171..1]
CYPH_CATRO - Peptidyl-prolyl cis-trans isomerase OS=Catharanthus roseus GN=PCKR1 PE=1 SV=1
261.0 [0..1] [171..1]
gi|90704803 - gi|90704803|dbj|BAE92296.1| putative peptidyl-prolyl cis-trans isomerase [Cryptomeria japonica]
260.0 [0..1] [171..1]
gi|18376589 - gi|18376589|emb|CAC81066.1| putative cyclosporin A-binding protein [Picea abies]
gi|116792557, gi... - gi|116792557|gb|ABK26413.1| unknown [Picea sitchensis], gi|116789016|gb|ABK25084.1| unknown [Picea s...
260.0 [0..1] [171..1]
gi|255538956, gi... - gi|255538956|ref|XP_002510543.1| cyclophilin, putative [Ricinus communis], gi|223551244|gb|EEF52730....
260.0 [0..2] [171..3]
gi|37722431 - gi|37722431|gb|AAN72439.1| cyclophilin [Kandelia candel]
260.0 [0..1] [171..1]

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Predicted Domain #1
Region A:
Residues: [1-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRSKVFFDI TIGGKASGRI VMELYDDVVP KTAGNFRALC TGENGIGKSG KPLHFKGSKF  60
   61 HRIIPNFMIQ GGDFTRGNGT GGESIYGEKF PDENFKEKHT GPGVLSMANA GPNTNGSQFF 120
  121 LCTVKTEWLD GKHVVFGRVV EGLDVVKAVE SNGSQSGKPV KDCMIADCGQ LKA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.39794
Match: 1dywA
Description: Cyclophilin (eukaryotic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein deacetylase activity 4.3775483906311 bayes_pls_golite062009
histone deacetylase activity 4.29026678196473 bayes_pls_golite062009
peptidyl-prolyl cis-trans isomerase activity 3.73853378771688 bayes_pls_golite062009
cis-trans isomerase activity 3.66963215732405 bayes_pls_golite062009
deacetylase activity 3.49940864924766 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3.01511519120932 bayes_pls_golite062009
RNA binding 2.94609837984526 bayes_pls_golite062009
isomerase activity 1.96529188741504 bayes_pls_golite062009
binding 1.46018233647024 bayes_pls_golite062009
mRNA binding 1.45537055700871 bayes_pls_golite062009
unfolded protein binding 1.38124355054041 bayes_pls_golite062009
nucleic acid binding 0.939772862764466 bayes_pls_golite062009
catalytic activity 0.748655649755714 bayes_pls_golite062009
hydrolase activity 0.493806105600863 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.408539130322443 bayes_pls_golite062009
drug binding 0.36339132904137 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.322244688184474 bayes_pls_golite062009
small conjugating protein ligase activity 0.286133802341887 bayes_pls_golite062009
histone binding 0.268719695649015 bayes_pls_golite062009
protein binding 0.130251391659493 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle