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View Structure Prediction Details

Protein: gpa-18
Organism: Caenorhabditis elegans
Length: 335 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gpa-18.

Description E-value Query
Range
Subject
Range
gi|114662614 - gi|114662614|ref|XP_510976.2| PREDICTED: guanine nucleotide binding protein, alpha activating polype...
371.0 [0..1] [334..206]

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Predicted Domain #1
Region A:
Residues: [1-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSAGSVDRG PIRTLVLGCM GAGKTSFIRQ MVKNHTKSIC LRRELYLYCV QLNLLNIYRE  60
   61 LKNVIEALEI PISEDQVTIL NNFDSKSTFT KQRFTQLDEY RHREVFPPKI IEAMKELFES 120
  121 GLYELCRLRQ RILPLPQNYH FLFQRGDDFM NPEYVPSELE IMMSYSQTCG LNRENVTCQG 180
  181 YKFELLEMPG HHLWRAKWAD YFDDPNLVVF VIDLSELCDP AFYNYFQKGY LENKTVTVFE 240
  241 SLVNNPVLAK VYWLLLFNKA DTFNDHSAGF DFRKLANHLD TADSARSFYR SQFTTKISKT 300
  301 RCFPHIVSLV NESQSVMMEM FKKIGKMHRE RPNLM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 100.0
Match: 1svkA
Description: Structure of the K180P mutant of Gi alpha subunit bound to AlF4 and GDP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
GTPase activity 4.8977602956056 bayes_pls_golite062009
guanyl nucleotide binding 2.37366263422025 bayes_pls_golite062009
GTP binding 2.15418131491052 bayes_pls_golite062009
G-protein-coupled receptor binding 2.06898720161422 bayes_pls_golite062009
binding 2.00548409930693 bayes_pls_golite062009
G-protein coupled receptor activity 1.63949223587737 bayes_pls_golite062009
purine ribonucleotide binding 1.21658213854831 bayes_pls_golite062009
ribonucleotide binding 1.21652144153182 bayes_pls_golite062009
purine nucleotide binding 1.21571071905795 bayes_pls_golite062009
nucleotide binding 1.20347573865566 bayes_pls_golite062009
molecular transducer activity 0.683309012097319 bayes_pls_golite062009
signal transducer activity 0.683309012097319 bayes_pls_golite062009
transmembrane receptor activity 0.661834961742057 bayes_pls_golite062009
receptor activity 0.633514002718998 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.398651949563863 bayes_pls_golite062009
guanyl ribonucleotide binding 0.372638007722845 bayes_pls_golite062009
pyrophosphatase activity 0.329606804913681 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.310343974731494 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.308125979591209 bayes_pls_golite062009
ATP binding 0.20901529484652 bayes_pls_golite062009
adenyl ribonucleotide binding 0.193888824779002 bayes_pls_golite062009
metabotropic serotonin receptor binding 0.178039386254807 bayes_pls_golite062009
adenyl nucleotide binding 0.176038316016909 bayes_pls_golite062009
protein binding 0.170837278876362 bayes_pls_golite062009
opioid receptor binding 0.105073376987609 bayes_pls_golite062009
mu-type opioid receptor binding 0.105073376987609 bayes_pls_golite062009
hydrolase activity 0.0340518447528398 bayes_pls_golite062009

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