YRC Public Data Repository - Protein Structure Prediction

Protein:	rbx-2
Organism:	Caenorhabditis elegans
Length:	112 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rbx-2.

Description	E-value	Query Range	Subject Range
gi\|50728692 - gi\|50728692\|ref\|XP_416239.1\| PREDICTED: similar to RBX1 protein [Gallus gallus]	91.0	[0..1]	[111..252]
gi\|114686561 - gi\|114686561\|ref\|XP_001167997.1\| PREDICTED: similar to RBX1 protein isoform 3 [Pan troglodytes]	90.0	[0..1]	[110..1]
gi\|39589782, gi\|... - gi\|39589782\|emb\|CAE67017.1\| Hypothetical protein CBG12418 [Caenorhabditis briggsae], gi\|187029546\|em... gi\|157746647 - gi\|157746647\|ref\|XP_001668419.1\| Hypothetical protein CBG12418 [Caenorhabditis briggsae AF16]	89.0	[0..6]	[109..908]
gi\|32411197, gi\|... - gi\|32411197\|ref\|XP_326079.1\| hypothetical protein [Neurospora crassa], gi\|28924726\|gb\|EAA33839.1\| hy... gi\|85109762 - gi\|85109762\|ref\|XP_963075.1\| hypothetical protein [Neurospora crassa OR74A]	89.0	[0..1]	[112..1]
gi\|113624403, gi... - gi\|50948261\|ref\|XP_483658.1\| putative RING-H2 finger protein RHG1a [Oryza sativa (japonica cultivar-...	88.0	[0..6]	[112..198]
gi\|78394982 - gi\|78394982\|gb\|AAI07832.1\| Rbx1 protein [Danio rerio]	88.0	[0..1]	[111..15]
gi\|238503442, gi... - gi\|238503442\|ref\|XP_002382954.1\| ubiquitin ligase subunit HrtA, putative [Aspergillus flavus NRRL335... gi\|169765261 - gi\|169765261\|ref\|XP_001817102.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83764956 - gi\|83764956\|dbj\|BAE55100.1\| unnamed protein product [Aspergillus oryzae]	88.0	[0..1]	[112..6]
gi\|57092733 - gi\|57092733\|ref\|XP_531722.1\| PREDICTED: similar to RING-box protein 1 (Rbx1) [Canis familiaris]	88.0	[0..1]	[109..101]
gi\|125809513, gi... - gi\|54636324\|gb\|EAL25727.1\| GA15425-PA [Drosophila pseudoobscura], gi\|125809513\|ref\|XP_001361150.1\| G...	88.0	[0..34]	[106..276]
gi\|159126214 - gi\|159126214\|gb\|EDP51330.1\| ubiquitin ligase subunit HrtA, putative [Aspergillus fumigatus A1163] gi\|66851689, gi\|... - gi\|70998662\|ref\|XP_754053.1\| ubiquitin ligase subunit HrtA [Aspergillus fumigatus Af293], gi\|6685168...	87.0	[0..1]	[112..6]

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Predicted Domain #1

Region A:
Residues: [1-112]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNSSNADSQ EGSTSAQKQK TANPSESRPF VLKKWNALAV WAWDVECDTC AICRVHLMEE  60
   61 CLRCQSEPSA ECYVVWGDCN HSFHHCCMTQ WIRQNNRCPL CQKDWVVSRT SK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.69897
Match:	1u6gB
Description:	Crystal Structure of The Cand1-Cul1-Roc1 Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ubiquitin-protein ligase activity	10.2497392096259	bayes_pls_golite062009
small conjugating protein ligase activity	10.0460587929138	bayes_pls_golite062009
acid-amino acid ligase activity	8.99384576623969	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	7.6988425139962	bayes_pls_golite062009
NEDD8 ligase activity	5.61847630780351	bayes_pls_golite062009
ligase activity	3.92677358871643	bayes_pls_golite062009
binding	2.58862749918018	bayes_pls_golite062009
protein binding	1.49775478023418	bayes_pls_golite062009
small conjugating protein-specific protease activity	1.2126425713931	bayes_pls_golite062009
ubiquitin-specific protease activity	1.03469202541773	bayes_pls_golite062009
transcription factor binding	0.90065892745057	bayes_pls_golite062009
transcription regulator activity	0.779340816536763	bayes_pls_golite062009
nucleic acid binding	0.708499177773075	bayes_pls_golite062009
hydrolase activity	0.52386813728704	bayes_pls_golite062009
cysteine-type peptidase activity	0.50197530717959	bayes_pls_golite062009
transcription repressor activity	0.393708074680332	bayes_pls_golite062009
ubiquitin thiolesterase activity	0.265769062717221	bayes_pls_golite062009
DNA binding	0.227671243150662	bayes_pls_golite062009
catalytic activity	0.14112008370434	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: