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View Structure Prediction Details

Protein: npp-17
Organism: Caenorhabditis elegans
Length: 373 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for npp-17.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
421.0 [0..1] [368..1168]

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Predicted Domain #1
Region A:
Residues: [1-373]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGSSGFGNK SMFGGSNIST STTTPAANTT QNDDFLVDGA PEDTIQVIKF SPTPQDKPML  60
   61 ACGSWDGTIR VWMFNDANTF EGKAQQNIPA PILDIAWIED SSKIFIACAD KEARLWDLAS 120
  121 NQVAVVGTHD GPVKTCHWIN GNNYQCLMTG SFDKTLRFWD MKNLPNQTQM AQIQLPERVY 180
  181 AADVLYPMAV VALANKHIKV YNLENGPTEV KDIESQLKFQ IRCISIFKDK SNQNPAGFAL 240
  241 GSIEGRVAVQ YVDVANPKDN FTFKCHRSAE LVNGFQEIYA VNDICFHPQH GTLVTIGSDG 300
  301 RYSMWDKDAR TKLKTSEPHP MPLTCCDVHS SGAFLVYALG YDWSRGHEGN TQPGSKIVIH 360
  361 KCIEDMKPRP TKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.39794
Match: 1vyhC
Description: PAF-AH Holoenzyme: Lis1/Alfa2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 3.1056443224755 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
actin binding 2.27900251096697 bayes_pls_golite062009
tubulin binding 2.01759734664395 bayes_pls_golite062009
microtubule binding 1.98090681825586 bayes_pls_golite062009
transcription regulator activity 1.95667720244696 bayes_pls_golite062009
nucleic acid binding 1.90457914882449 bayes_pls_golite062009
transcription repressor activity 1.6725482369574 bayes_pls_golite062009
snoRNA binding 1.61553185503007 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.59258100795958 bayes_pls_golite062009
structural molecule activity 1.47448876401574 bayes_pls_golite062009
DNA binding 1.38475369554616 bayes_pls_golite062009
dynactin binding 1.29574819250251 bayes_pls_golite062009
protein binding 1.21879977456466 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
protein transporter activity 0.964340340346761 bayes_pls_golite062009
transcription corepressor activity 0.963909191437161 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.937944931047515 bayes_pls_golite062009
dynein binding 0.92848877230786 bayes_pls_golite062009
transcription factor activity 0.804334981068351 bayes_pls_golite062009
substrate-specific transporter activity 0.734793983890004 bayes_pls_golite062009
signal transducer activity 0.577438981735303 bayes_pls_golite062009
molecular transducer activity 0.577438981735303 bayes_pls_golite062009
actin filament binding 0.554537899540618 bayes_pls_golite062009
acid-amino acid ligase activity 0.535041400676017 bayes_pls_golite062009
0.53274018413176 bayes_pls_golite062009
transcription factor binding 0.412844855996155 bayes_pls_golite062009
receptor activity 0.322599767074871 bayes_pls_golite062009
transcription cofactor activity 0.19391619547146 bayes_pls_golite062009
hydrolase activity 0.181211933860468 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.168317261786777 bayes_pls_golite062009
histone binding 0.166694897714113 bayes_pls_golite062009
kinase activity 0.127621956173205 bayes_pls_golite062009
structural constituent of cytoskeleton 0.118975415284669 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009

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