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View Structure Prediction Details

Protein: glt-3
Organism: Caenorhabditis elegans
Length: 532 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for glt-3.

Description E-value Query
Range		 Subject
Range
SLC1A7 - solute carrier family 1 (glutamate transporter), member 7
 443.0 [0..4] [531..15]

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Predicted Domain #1
Region A:
Residues: [1-459] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGMKKDLLLV LTIESVVLGV VLGFVIRPFN PSNDTISLIG FPGEIFMQIV EMMILPLIMS  60
   61 SVISALAQVR ARDARRIGIV TIIYYMITTF LATFTGIILV SSIHPGDPEL IHELGEGTLE 120
  121 NTALSTLDTF LDQIRNMFPE NIIQATFQQV QTEYMPIKPS RVRNATSMNM TSEVLHKQTL 180
  181 TYTNEMNVLG LIVFCSGFGI ILSILGDQAR LMINFFIVLD AIIMRWISAL MWCYPIGILS 240
  241 LVCKNIIDID NLTETAQALA MYVVTVICGL MIHSLLTLPL LYFLVTKKSP FAFMTGMLQA 300
  301 LATAFGTASS GATLPVTFRA LEENLKIDRR VTRFVLPLGA TITMDGTALY EAVAVIFIAQ 360
  361 LHNIKLSLMD LVTISITTTV ASIGSGSVPA GLDTIVIVLT TVGLPAKDLS LLLTVDWLLD 420
  421 RIRTSVNVLG DSFGAGIIHH LTRSSLLEAD TDELIRQIR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.69897
Match: 1xfhA
Description: Structure of glutamate transporter homolog from Pyrococcus horikoshii
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
high-affinity glutamate transmembrane transporter activity 9.03564241021137 bayes_pls_golite062009
dicarboxylic acid transmembrane transporter activity 8.28237742051097 bayes_pls_golite062009
L-hydroxyproline transmembrane transporter activity 8.15113968525681 bayes_pls_golite062009
serine transmembrane transporter activity 8.15113968525681 bayes_pls_golite062009
alanine transmembrane transporter activity 8.15113968525681 bayes_pls_golite062009
L-threonine transmembrane transporter activity 8.15113968525681 bayes_pls_golite062009
L-serine transmembrane transporter activity 8.15113968525681 bayes_pls_golite062009
L-proline transmembrane transporter activity 8.15113968525681 bayes_pls_golite062009
L-alanine transmembrane transporter activity 8.15113968525681 bayes_pls_golite062009
L-aspartate transmembrane transporter activity 6.32804156021168 bayes_pls_golite062009
carboxylic acid transmembrane transporter activity 6.20769381184606 bayes_pls_golite062009
organic acid transmembrane transporter activity 6.19258658226115 bayes_pls_golite062009
anion:cation symporter activity 5.39486898992441 bayes_pls_golite062009
transporter activity 5.14616859489508 bayes_pls_golite062009
L-cystine transmembrane transporter activity 5.11451286998367 bayes_pls_golite062009
substrate-specific transporter activity 5.08516306839475 bayes_pls_golite062009
transmembrane transporter activity 5.06400974103865 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.03536308870823 bayes_pls_golite062009
ion transmembrane transporter activity 4.56245375639148 bayes_pls_golite062009
acidic amino acid transmembrane transporter activity 4.55490142908046 bayes_pls_golite062009
L-glutamate transmembrane transporter activity 4.55490142908046 bayes_pls_golite062009
cation transmembrane transporter activity 4.38524103588396 bayes_pls_golite062009
active transmembrane transporter activity 4.37939766329509 bayes_pls_golite062009
sulfur amino acid transmembrane transporter activity 4.37598805288869 bayes_pls_golite062009
secondary active transmembrane transporter activity 3.93820513423101 bayes_pls_golite062009
amine transmembrane transporter activity 3.7335977004076 bayes_pls_golite062009
L-amino acid transmembrane transporter activity 3.55306444119183 bayes_pls_golite062009
solute:cation symporter activity 3.47181854698038 bayes_pls_golite062009
symporter activity 3.47181854698038 bayes_pls_golite062009
organic acid:sodium symporter activity 3.44677545809568 bayes_pls_golite062009
amino acid transmembrane transporter activity 3.22640982674356 bayes_pls_golite062009
solute:hydrogen symporter activity 3.11518167297447 bayes_pls_golite062009
neutral amino acid transmembrane transporter activity 2.88609411192338 bayes_pls_golite062009
anion transmembrane transporter activity 2.02127810434029 bayes_pls_golite062009
solute:sodium symporter activity 1.76557983021416 bayes_pls_golite062009
C4-dicarboxylate transmembrane transporter activity 1.60815006184662 bayes_pls_golite062009
protein binding 1.39188421476117 bayes_pls_golite062009
binding 1.33552537079117 bayes_pls_golite062009
amine binding 1.22219692417544 bayes_pls_golite062009
amino acid binding 1.0487791191866 bayes_pls_golite062009
cation:amino acid symporter activity 0.85052491897986 bayes_pls_golite062009
glutamate:sodium symporter activity 0.553718735358201 bayes_pls_golite062009
monocarboxylic acid transmembrane transporter activity 0.31624582149961 bayes_pls_golite062009
neurotransmitter transporter activity 0.25304246415333 bayes_pls_golite062009
passive transmembrane transporter activity 0.119412711778045 bayes_pls_golite062009
channel activity 0.119412711778045 bayes_pls_golite062009
substrate-specific channel activity 0.0999184515491418 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [460-532] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDIDILNNPH QDTLPISHHS VQSTIQNTQN AMQAPHVYSK SARASFAPIP NEEERKALLK  60
   61 ESIALNKSDT HIV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle