YRC Public Data Repository - Protein Structure Prediction

Protein:	CE03954
Organism:	Caenorhabditis elegans
Length:	274 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE03954.

Description	E-value	Query Range	Subject Range
FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima GN=fabG PE=3 SV=1 FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / D...	289.0	[0..3]	[265..2]
gi\|146296617, gi... - gi\|82501013\|ref\|ZP_00886394.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Caldicellulosiruptor sacc...	284.0	[0..1]	[265..1]
gi\|255313843 - gi\|255313843\|ref\|ZP_05355426.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255516524 - gi\|255516524\|ref\|ZP_05384200.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255649624 - gi\|255649624\|ref\|ZP_05396526.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|254974717 - gi\|254974717\|ref\|ZP_05271189.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255092105 - gi\|255092105\|ref\|ZP_05321583.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile CI... gi\|90575404, gi\|... - gi\|90575404\|ref\|ZP_01231888.1\| hypothetical protein CdifQ_02001165 [Clostridium difficile QCD-32g58]...	280.0	[0..1]	[265..1]
gi\|115250215, gi... - gi\|126698778\|ref\|YP_001087675.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile 6... gi\|255306086 - gi\|255306086\|ref\|ZP_05350258.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile AT... gi\|255100197 - gi\|255100197\|ref\|ZP_05329174.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC...	280.0	[0..1]	[265..1]
gi\|18310052, gi\|... - gi\|18310052\|ref\|NP_561986.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens st...	278.0	[0..4]	[265..2]
gi\|11498806, gi\|... - gi\|2649386\|gb\|AAB90046.1\| 2-deoxy-D-gluconate 3-dehydrogenase (kduD) [Archaeoglobus fulgidus DSM 430... gi\|7431025 - pir\|\|F69400 2-deoxy-D-gluconate 3-dehydrogenase (kduD) homolog - Archaeoglobus fulgidus	275.0	[0..1]	[264..30]
gi\|91184216, gi\|... - gi\|91217712\|ref\|ZP_01254669.1\| putative 3-oxoacyl-[acyl-carrier protein] reductase [Psychroflexus to...	275.0	[0..1]	[264..8]
gi\|28210515, gi\|... - gi\|28210515\|ref\|NP_781459.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium tetani E88], g...	275.0	[0..4]	[263..6]
gi\|168210762, gi... - gi\|170711222\|gb\|EDT23404.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens B st... gi\|110675446, gi... - gi\|110800799\|ref\|YP_695772.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens A... gi\|170660709, gi... - gi\|170660709\|gb\|EDT13392.1\| 3-oxoacyl- reductase [Clostridium perfringens E str. JGS1987], gi\|168207...	275.0	[0..4]	[265..2]
gi\|89098688, gi\|... - gi\|89098688\|ref\|ZP_01171570.1\| beta-ketoacyl-acyl carrier protein reductase [Bacillus sp. NRRL B-149...	274.0	[0..3]	[265..2]

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Predicted Domain #1

Region A:
Residues: [1-274]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARFTDKVAI ITGSSNGIGR ATAVLLATDG AKVTITGRDA ARLEETRQAI LKAGISATNV  60
   61 NSVVADVTTA EGQDLLISST LDKFGKINIL INNAGANIPD SQGQTRTKCS IENLTKMFQL 120
  121 NLQSVVEMVQ KVRPHLAKTR GEIVNISSIG AGPAAQPASP YYSSAKAALD QYSRCAAIDL 180
  181 ISEGIRINVV QPGFVSTGFS TAARGLSADE SVKFYDLMGS LPHCIPAGYC GQPDHLASVI 240
  241 AFLVDRKVSE YIVGQTIIAD GGSSLVIGCH APRQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	67.0
Match:	1spxA
Description:	Crystal Structure of Glucose Dehydrogenase of Caenorhabditis Elegans in the Apo-Form
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	3.09625241707629	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	3.06391460989761	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	3.02758902218302	bayes_pls_golite062009
retinol dehydrogenase activity	2.50453100919665	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	2.01043991420942	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	1.84548524949714	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
steroid dehydrogenase activity	1.75109362865449	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.65338499044318	bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.55012034958204	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.47309297191111	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	1.248916824872	bayes_pls_golite062009
fatty acid synthase activity	1.23679054027553	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	1.1634925015191	bayes_pls_golite062009
alcohol binding	1.07158175924364	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	1.01627645289834	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	0.867909552357575	bayes_pls_golite062009
binding	0.784517759335365	bayes_pls_golite062009
retinal dehydrogenase activity	0.69372321031969	bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity	0.604742541607263	bayes_pls_golite062009
3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity	0.583772223704381	bayes_pls_golite062009
testosterone 17-beta-dehydrogenase activity	0.532187027260366	bayes_pls_golite062009
DNA binding	0.525227236870065	bayes_pls_golite062009
nucleic acid binding	0.459537641913493	bayes_pls_golite062009
enoyl-CoA hydratase activity	0.439912268968251	bayes_pls_golite062009
retinol binding	0.343379136183648	bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent	0.311551606659739	bayes_pls_golite062009
transcription regulator activity	0.152651308844322	bayes_pls_golite062009
ethanol binding	0.0448614072391299	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: