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View Structure Prediction Details

Protein: sfp1
Organism: Schizosaccharomyces pombe
Length: 442 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sfp1.

Description E-value Query
Range
Subject
Range
gi|73947291 - gi|73947291|ref|XP_541354.2| PREDICTED: similar to Zinc finger protein 606 (Zinc finger protein 328)...
344.0 [0..40] [442..2476]
gi|76687658 - gi|76687658|ref|XP_875883.1| PREDICTED: similar to Zinc finger protein Kr18 (HKr18) [Bos taurus]
317.0 [0..40] [442..283]
gi|109125970 - gi|109125970|ref|XP_001115785.1| PREDICTED: similar to zinc finger protein 665 [Macaca mulatta]
313.0 [0..18] [442..245]
ZNF287 - zinc finger protein 287
311.0 [0..51] [441..356]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSLALPINK PSHHNVNYNG NSFNSIHATS FGMSPQSWGN SFSGQAWLRD TIPSLSNVVE  60
   61 SQTIPEEDST SYLNRLEEAF CRDFRCCGQT LEDLHQLIHH YEE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.0
Match: 2ct1A
Description: Solution Structure of the zinc finger domain of Transcriptional repressor CTCF protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.47951889934838 bayes_pls_golite062009
nucleic acid binding 4.35187767955595 bayes_pls_golite062009
DNA binding 4.31051339571017 bayes_pls_golite062009
transcription factor activity 3.28758716579796 bayes_pls_golite062009
binding 2.99742524370422 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.05542379535543 bayes_pls_golite062009
transcription activator activity 1.97757778483124 bayes_pls_golite062009
transcription repressor activity 1.44763794968807 bayes_pls_golite062009
sequence-specific DNA binding 1.26862497534835 bayes_pls_golite062009
chromatin binding 1.26688155139311 bayes_pls_golite062009
transcription factor binding 1.23738346570539 bayes_pls_golite062009
protein binding 0.952480850696098 bayes_pls_golite062009
structure-specific DNA binding 0.77786753211873 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.776754909146767 bayes_pls_golite062009
transcription cofactor activity 0.627794176881836 bayes_pls_golite062009
double-stranded DNA binding 0.356308409912021 bayes_pls_golite062009
catalytic activity 0.263007611601737 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [104-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QHAVLATDSA VPQEYSLDSN NAAQSNHSHI QALKQRERIR MHDLADQLGT SEISDNSAVL  60
   61 PFAFPANGGA PGPYRVSVVV PAAAAAAAAA ASSDMSSDEA SSQAETTGTP KKMPES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [220-442]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LVMDASSPLS DMSMSIDVGE SAANNVFAFN QKDMVDSTYL PPFNYDHDVF SFAPSVASAD  60
   61 QFTESSMSPT PEVVSPAATN SAISSPFVRK SSSDLEAKPS KKQRSTPAFS HDSPLTIDYP 120
  121 GSNLVVVDKP YKCPVPNCDK AYKNQNGLKY HKLHGHCSPI TTPTPAPIPH QGFVVENKPY 180
  181 RCEVCSKRYK NLNGLKYHRT HSHLQVSMAQ AQREVQMNFM RTA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.69897
Match: 2i13A
Description: No description for 2i13A was found.

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