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View Structure Prediction Details

Protein: sfp1
Organism: Schizosaccharomyces pombe
Length: 442 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sfp1.

Description E-value Query
Range
Subject
Range
gi|73947291 - gi|73947291|ref|XP_541354.2| PREDICTED: similar to Zinc finger protein 606 (Zinc finger protein 328)...
344.0 [0..40] [442..2476]
gi|76687658 - gi|76687658|ref|XP_875883.1| PREDICTED: similar to Zinc finger protein Kr18 (HKr18) [Bos taurus]
317.0 [0..40] [442..283]
gi|109125970 - gi|109125970|ref|XP_001115785.1| PREDICTED: similar to zinc finger protein 665 [Macaca mulatta]
313.0 [0..18] [442..245]
ZNF287 - zinc finger protein 287
311.0 [0..51] [441..356]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSLALPINK PSHHNVNYNG NSFNSIHATS FGMSPQSWGN SFSGQAWLRD TIPSLSNVVE  60
   61 SQTIPEEDST SYLNRLEEAF CRDFRCCGQT LEDLHQLIHH YEE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.0
Match: 2ct1A
Description: Solution Structure of the zinc finger domain of Transcriptional repressor CTCF protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.47951889934838 bayes_pls_golite062009
nucleic acid binding 4.35187767955595 bayes_pls_golite062009
DNA binding 4.31051339571017 bayes_pls_golite062009
transcription factor activity 3.28758716579796 bayes_pls_golite062009
binding 2.99742524370422 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.05542379535543 bayes_pls_golite062009
transcription activator activity 1.97757778483124 bayes_pls_golite062009
transcription repressor activity 1.44763794968807 bayes_pls_golite062009
sequence-specific DNA binding 1.26862497534835 bayes_pls_golite062009
chromatin binding 1.26688155139311 bayes_pls_golite062009
transcription factor binding 1.23738346570539 bayes_pls_golite062009
protein binding 0.952480850696098 bayes_pls_golite062009
structure-specific DNA binding 0.77786753211873 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.776754909146767 bayes_pls_golite062009
transcription cofactor activity 0.627794176881836 bayes_pls_golite062009
double-stranded DNA binding 0.356308409912021 bayes_pls_golite062009
catalytic activity 0.263007611601737 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [104-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QHAVLATDSA VPQEYSLDSN NAAQSNHSHI QALKQRERIR MHDLADQLGT SEISDNSAVL  60
   61 PFAFPANGGA PGPYRVSVVV PAAAAAAAAA ASSDMSSDEA SSQAETTGTP KKMPES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [220-442]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LVMDASSPLS DMSMSIDVGE SAANNVFAFN QKDMVDSTYL PPFNYDHDVF SFAPSVASAD  60
   61 QFTESSMSPT PEVVSPAATN SAISSPFVRK SSSDLEAKPS KKQRSTPAFS HDSPLTIDYP 120
  121 GSNLVVVDKP YKCPVPNCDK AYKNQNGLKY HKLHGHCSPI TTPTPAPIPH QGFVVENKPY 180
  181 RCEVCSKRYK NLNGLKYHRT HSHLQVSMAQ AQREVQMNFM RTA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.69897
Match: 2i13A
Description: No description for 2i13A was found.

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