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View Structure Prediction Details

Protein: SPBC36B7.05c
Organism: Schizosaccharomyces pombe
Length: 279 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC36B7.05c.

Description E-value Query
Range
Subject
Range
gi|37932591 - gi|37932591|gb|AAP76435.1| RAG1 protein [Protoxerus stangeri]
105.0 [0..37] [279..58]
gi|34223829 - gi|34223829|gb|AAQ63083.1| recombination activating gene 1 [Rhipidomys mastacalis]
104.0 [0..37] [279..72]
gi|37932575 - gi|37932575|gb|AAP76427.1| RAG1 protein [Sciurotamias davidianus]
103.0 [0..37] [279..64]
gi|37932597 - gi|37932597|gb|AAP76438.1| RAG1 protein [Paraxerus ochraceus]
103.0 [0..37] [279..63]
gi|37932561 - gi|37932561|gb|AAP76420.1| RAG1 protein [Tamiops swinhoei]
102.0 [0..37] [279..63]
gi|37932555 - gi|37932555|gb|AAP76417.1| RAG1 protein [Microsciurus flaviventer]
102.0 [0..37] [279..68]
gi|37932543 - gi|37932543|gb|AAP76411.1| RAG1 protein [Glaucomys volans]
102.0 [0..37] [279..68]
gi|34223779 - gi|34223779|gb|AAQ63058.1| recombination activating gene 1 [Cricetomys gambianus]
101.0 [0..37] [279..61]
gi|37932589 - gi|37932589|gb|AAP76434.1| RAG1 protein [Heliosciurus undulatus]
101.0 [0..37] [279..42]
gi|76636278 - gi|76636278|ref|XP_872414.1| PREDICTED: recombination activating gene 1 [Bos taurus]
101.0 [0..37] [279..99]

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Predicted Domain #1
Region A:
Residues: [1-75]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEDETTYPE ALRRLLIETP AAIWQLDDES AQCNNCGGPF TWFRRRHHCR WCGKLFCYNC  60
   61 CNSFAKLPVS SVSVD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.522879
Match: 1z2qA
Description: High-resolution solution structure of the LM5-1 FYVE domain from Leishmania major
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [76-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTEDLIPQDM FIRDPDFLAN DNDDDNDSQD SSWINVRVCV NCRQQLSELK ELDLPYPITT  60
   61 CLNDDTTTRS NNQVIQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [152-279]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSCGNNLQRI EEPDDFVECP VCYAPLSSFK TLSERESHVA NCLSNNSSSP RNMTEFLKHA  60
   61 RRYISMQLSE TSPCLGQECI ICFEEFAAGD RVARIEYCLC IFHLKCYRDW LSTGAAGCPV 120
  121 HAATLHLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.09691
Match: 1rmdA
Description: RAG1 DIMERIZATION DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 5.65442784325159 bayes_pls_golite062009
small conjugating protein ligase activity 5.55686022186257 bayes_pls_golite062009
acid-amino acid ligase activity 4.59153177011595 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 2.57382484274962 bayes_pls_golite062009
binding 2.19426901055464 bayes_pls_golite062009
protein binding 1.73461977726143 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.2126425713931 bayes_pls_golite062009
ubiquitin-specific protease activity 1.03469202541773 bayes_pls_golite062009
nucleic acid binding 0.708499177773075 bayes_pls_golite062009
ligase activity 0.63517530468004 bayes_pls_golite062009
transcription regulator activity 0.553991532499653 bayes_pls_golite062009
cysteine-type peptidase activity 0.50197530717959 bayes_pls_golite062009
ubiquitin thiolesterase activity 0.265769062717221 bayes_pls_golite062009
DNA binding 0.227671243150662 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
hydrolase activity 0.0941589668589109 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle