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View Structure Prediction Details

Protein: SPBC36B7.05c
Organism: Schizosaccharomyces pombe
Length: 279 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC36B7.05c.

Description E-value Query
Range
Subject
Range
gi|37932591 - gi|37932591|gb|AAP76435.1| RAG1 protein [Protoxerus stangeri]
105.0 [0..37] [279..58]
gi|34223829 - gi|34223829|gb|AAQ63083.1| recombination activating gene 1 [Rhipidomys mastacalis]
104.0 [0..37] [279..72]
gi|37932575 - gi|37932575|gb|AAP76427.1| RAG1 protein [Sciurotamias davidianus]
103.0 [0..37] [279..64]
gi|37932597 - gi|37932597|gb|AAP76438.1| RAG1 protein [Paraxerus ochraceus]
103.0 [0..37] [279..63]
gi|37932561 - gi|37932561|gb|AAP76420.1| RAG1 protein [Tamiops swinhoei]
102.0 [0..37] [279..63]
gi|37932555 - gi|37932555|gb|AAP76417.1| RAG1 protein [Microsciurus flaviventer]
102.0 [0..37] [279..68]
gi|37932543 - gi|37932543|gb|AAP76411.1| RAG1 protein [Glaucomys volans]
102.0 [0..37] [279..68]
gi|34223779 - gi|34223779|gb|AAQ63058.1| recombination activating gene 1 [Cricetomys gambianus]
101.0 [0..37] [279..61]
gi|37932589 - gi|37932589|gb|AAP76434.1| RAG1 protein [Heliosciurus undulatus]
101.0 [0..37] [279..42]
gi|76636278 - gi|76636278|ref|XP_872414.1| PREDICTED: recombination activating gene 1 [Bos taurus]
101.0 [0..37] [279..99]

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Predicted Domain #1
Region A:
Residues: [1-75]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEDETTYPE ALRRLLIETP AAIWQLDDES AQCNNCGGPF TWFRRRHHCR WCGKLFCYNC  60
   61 CNSFAKLPVS SVSVD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.522879
Match: 1z2qA
Description: High-resolution solution structure of the LM5-1 FYVE domain from Leishmania major
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [76-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTEDLIPQDM FIRDPDFLAN DNDDDNDSQD SSWINVRVCV NCRQQLSELK ELDLPYPITT  60
   61 CLNDDTTTRS NNQVIQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [152-279]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSCGNNLQRI EEPDDFVECP VCYAPLSSFK TLSERESHVA NCLSNNSSSP RNMTEFLKHA  60
   61 RRYISMQLSE TSPCLGQECI ICFEEFAAGD RVARIEYCLC IFHLKCYRDW LSTGAAGCPV 120
  121 HAATLHLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.09691
Match: 1rmdA
Description: RAG1 DIMERIZATION DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 5.65442784325159 bayes_pls_golite062009
small conjugating protein ligase activity 5.55686022186257 bayes_pls_golite062009
acid-amino acid ligase activity 4.59153177011595 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 2.57382484274962 bayes_pls_golite062009
binding 2.19426901055464 bayes_pls_golite062009
protein binding 1.73461977726143 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.2126425713931 bayes_pls_golite062009
ubiquitin-specific protease activity 1.03469202541773 bayes_pls_golite062009
nucleic acid binding 0.708499177773075 bayes_pls_golite062009
ligase activity 0.63517530468004 bayes_pls_golite062009
transcription regulator activity 0.553991532499653 bayes_pls_golite062009
cysteine-type peptidase activity 0.50197530717959 bayes_pls_golite062009
ubiquitin thiolesterase activity 0.265769062717221 bayes_pls_golite062009
DNA binding 0.227671243150662 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
hydrolase activity 0.0941589668589109 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle