YRC Public Data Repository - Protein Structure Prediction

Protein:	arp9
Organism:	Schizosaccharomyces pombe
Length:	523 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for arp9.

Description	E-value	Query Range	Subject Range
gi\|109489498 - gi\|109489498\|ref\|XP_001076100.1\| PREDICTED: similar to Actin, cytoplasmic 2 (Gamma-actin) [Rattus no...	481.0	[0..2]	[522..309]
gi\|223855 - gi\|223855\|prf\|\|1002250A actin	473.0	[0..4]	[522..1]
gi\|194130965, gi... - gi\|195340496\|ref\|XP_002036849.1\| GM12447 [Drosophila sechellia], gi\|194130965\|gb\|EDW53008.1\| GM12447... gi\|195401955, gi... - gi\|195401955\|ref\|XP_002059576.1\| GJ14747 [Drosophila virilis], gi\|194147283\|gb\|EDW62998.1\| GJ14747 [... gi\|195432731, gi... - gi\|195432731\|ref\|XP_002064370.1\| GK20124 [Drosophila willistoni], gi\|194160455\|gb\|EDW75356.1\| GK2012... gi\|195480603, gi... - gi\|195480603\|ref\|XP_002101323.1\| Act57B [Drosophila yakuba], gi\|194188847\|gb\|EDX02431.1\| Act57B [Dro... gi\|89473786, gi\|... - gi\|89473786\|gb\|ABD72705.1\| putative actin [Acyrthosiphon pisum], gi\|187109134\|ref\|NP_001119672.1\| ac... gi\|195565315, gi... - gi\|195565315\|ref\|XP_002106247.1\| GD16764 [Drosophila simulans], gi\|194203621\|gb\|EDX17197.1\| GD16764 ... ACT4_BOMMO - Actin, cytoplasmic A4 OS=Bombyx mori GN=A4 PE=2 SV=1 gi\|91088365, gi\|... - gi\|91088369\|ref\|XP_976070.1\| PREDICTED: similar to Actin-5C isoform 3 [Tribolium castaneum], gi\|9108... gi\|220947776, gi... - gi\|220957086\|gb\|ACL91086.1\| Act5C-PA [synthetic construct], gi\|220947776\|gb\|ACL86431.1\| Act5C-PA [sy... gi\|170048737, gi... - gi\|170048737\|ref\|XP_001870756.1\| conserved hypothetical protein [Culex quinquefasciatus], gi\|1678707... gi\|190648678, gi... - gi\|194889160\|ref\|XP_001977029.1\| GG18797 [Drosophila erecta], gi\|190648678\|gb\|EDV45956.1\| GG18797 [D... gi\|193892986, gi... - gi\|195046398\|ref\|XP_001992145.1\| GH24372 [Drosophila grimshawi], gi\|193892986\|gb\|EDV91852.1\| GH24372... gi\|125981707\|ref... - GA17886-PA [Drosophila pseudoobscura], GA17886 [Drosophila pseudoobscura pseudoobscura] gi\|193907820, gi... - gi\|195129856\|ref\|XP_002009370.1\| GI15312 [Drosophila mojavensis], gi\|193907820\|gb\|EDW06687.1\| GI1531... gi\|195166956, gi... - gi\|195166956\|ref\|XP_002024300.1\| GL14888 [Drosophila persimilis], gi\|194107673\|gb\|EDW29716.1\| GL1488... FBpp0311818, Act... - The gene Actin 5C is referred to in FlyBase by the symbol Dmel\Act5C (CG4027, FBgn0000042). It is a ... ACT5C_ANOGA - Actin-5C OS=Anopheles gambiae GN=Act5C PE=2 SV=1 gi\|54643168, gi\|... - gi\|54643168\|gb\|EAL31912.1\| GA17886 [Drosophila pseudoobscura pseudoobscura], gi\|125981707\|ref\|XP_001... gi\|157128681, gi... - gi\|157128681\|ref\|XP_001655176.1\| actin [Aedes aegypti], gi\|157128679\|ref\|XP_001655175.1\| actin [Aede... gi\|52630919 - gi\|52630919\|gb\|AAU84923.1\| putative actin [Toxoptera citricida] ACT3B_HELAM - Actin-A3b, cytoplasmic OS=Helicoverpa armigera GN=actA3b PE=2 SV=1 gi\|118780938, gi... - gi\|58381342\|ref\|XP_311177.2\| ENSANGP00000019055 [Anopheles gambiae str. PEST], gi\|55242984\|gb\|EAA068...	473.0	[0..1]	[522..1]
gi\|477248 - gi\|477248\|pir\|\|A48449 Actin-1A - nematode (Onchocerca volvulus) gi\|170587332, gi... - gi\|170587334\|ref\|XP_001898432.1\| actin 1 [Brugia malayi], gi\|170587332\|ref\|XP_001898431.1\| actin 1 [...	472.0	[0..1]	[522..1]
gi\|59894747 - gi\|59894747\|gb\|AAX11193.1\| actin [Ixodes ricinus]	472.0	[0..6]	[522..1]
gi\|45269029 - gi\|45269029\|gb\|AAS55927.1\| cytoskeletal beta actin [Sus scrofa]	472.0	[0..2]	[522..29]
gi\|66549344, gi\|... - gi\|66549344\|ref\|XP_623381.1\| PREDICTED: similar to Actin-5C isoform 2 [Apis mellifera], gi\|48137684\|...	472.0	[0..1]	[522..1]
gi\|19526211, gi\|... - gi\|19526213\|gb\|AAL89658.1\|AF286060_1 cytoplasmic actin A3a1 [Helicoverpa zea], gi\|19526211\|gb\|AAL896... gi\|28070937 - gi\|28070937\|emb\|CAD58315.1\| non-muscle actin [Manduca sexta] ACT3A_HELAM - Actin, cytoplasmic A3a OS=Helicoverpa armigera GN=actA3a PE=2 SV=1 gi\|154091302 - gi\|154091302\|gb\|ABS57458.1\| actin 1 [Heliconius erato]	472.0	[0..1]	[522..1]

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Predicted Domain #1

Region A:
Residues: [1-523]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSFRDDHII VIQTGSLYHR ATFGLAESLE PPTIRVRTRV GKNDNGEYVF TNKEDINMED  60
   61 PNVKTDETKV ETSESTSEQP SNSNVTEEKN MGSSFHSECK VDDFTPLPNE IQPIQRGRVV 120
  121 DWEALKAFWK HLYSLLLKDP NDTTFRYPVC LVIPTYWSLY DRELATQFFF EECQVPGFTI 180
  181 AYEPLMGLYA IGILHGLVID IGYEKTDITP ILDGQIIFTA TQQLPLGGRY MTQHLQNLLR 240
  241 ESLPTLKSSG QYVSKEDITE LFAEQVKCSE IAQVVRDEQD TAKDPVKALT STNNVEEEDP 300
  301 AEDIGKIIAS GQTRAYLAQK EREKNGESEK DEKPDNTDVE FQTIAIEPLG DCIVGRERFK 360
  361 ICEPIFHRPS NETVSLPEAI YITIKNYAAN YKRRNDLWEN IIVLGCGSRI RGFRECLIQQ 420
  421 LQFKYQLSGS LEPYYAAQGT DSILGMTTMP PTPYPALINP CKILPDYFPS WKPDAGTNAM 480
  481 FEELAFLGGS IVAKTSFNES VSSHYVTLEE YAQHGPTAIH TKQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	133.0
Match:	1nlvA
Description:	Actin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
histone acetyltransferase activity	4.28232216932019	bayes_pls_golite062009
lysine N-acetyltransferase activity	4.28232216932019	bayes_pls_golite062009
structural constituent of cytoskeleton	3.14961582364442	bayes_pls_golite062009
cytoskeletal protein binding	3.11425505645918	bayes_pls_golite062009
actin binding	2.955791490673	bayes_pls_golite062009
N-acetyltransferase activity	2.69348633032984	bayes_pls_golite062009
N-acyltransferase activity	2.44825347420194	bayes_pls_golite062009
structural molecule activity	2.37892721989886	bayes_pls_golite062009
binding	2.11855816699924	bayes_pls_golite062009
transcription regulator activity	2.09111975841662	bayes_pls_golite062009
acetyltransferase activity	2.07817518361957	bayes_pls_golite062009
protein binding	2.00711904074672	bayes_pls_golite062009
nucleic acid binding	1.84294882554466	bayes_pls_golite062009
DNA binding	1.70014394990425	bayes_pls_golite062009
actin filament binding	1.46443668299938	bayes_pls_golite062009
myosin binding	1.42865156375885	bayes_pls_golite062009
transcription activator activity	1.35676801272576	bayes_pls_golite062009
transporter activity	1.2883466875237	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	1.19428728049016	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.16749728168925	bayes_pls_golite062009
kinase activity	1.11102445353265	bayes_pls_golite062009
transcription factor activity	1.06678984888387	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.953663805249074	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.900931843471417	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.898645342556399	bayes_pls_golite062009
pyrophosphatase activity	0.875671218597808	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.78242344952806	bayes_pls_golite062009
ATPase activity	0.687771333492666	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.574998559133169	bayes_pls_golite062009
substrate-specific transporter activity	0.541702142383339	bayes_pls_golite062009
nucleosome binding	0.329990231856661	bayes_pls_golite062009
catalytic activity	0.296484721581333	bayes_pls_golite062009
carbohydrate kinase activity	0.123282448317819	bayes_pls_golite062009
transferase activity	0.105619024604158	bayes_pls_golite062009
acyltransferase activity	0.0596003372263518	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	0.0568891812635073	bayes_pls_golite062009
chromatin binding	0.0489277194984092	bayes_pls_golite062009
unfolded protein binding	0.0304569608189402	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: