| Protein: | hst4 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 415 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hst4.
| Description | E-value | Query Range |
Subject Range |
|
|
305.0 | [0..17] | [414..81] |
|
|
292.0 | [0..11] | [409..86] |
|
|
291.0 | [0..6] | [413..74] |
|
|
281.0 | [0..3] | [396..83] |
|
|
278.0 | [0..40] | [407..15] |
|
|
276.0 | [0..11] | [410..220] |
|
|
274.0 | [0..3] | [390..92] |
|
|
268.0 | [0..17] | [379..3] |
|
|
268.0 | [0..43] | [394..23] |
|
Region A: Residues: [1-415] |
1 11 21 31 41 51
| | | | | |
1 MKVEEHVPLI QESRKRKCQS SENASKRQQL LSKLPLRLHT GNENVDLSPL VSAIRKAKRI 60
61 VVVTGAGISC DAGIPDFRSS EGLFSSLRAE YKLNCSGKEL FDGSVYRDLK SVNIFHAMIR 120
121 KLHMLSNNAR PTDFHLFLSQ LAQESKLLRL YTQNIDFLET RLEGLQTCIP LPQSAPWPTT 180
181 IPLHGTLEVV SCTRCSFLKK FNPDIFDRNG VTVCPDCKTE NEVRRIAGKR SVIEGCLRPR 240
241 IVLYNEIHPD SESIGSVCSQ DLKSRPDCLI VAGTSCKIPG VKRIIKEMSN CVHKQKGNVI 300
301 WLNYDEPTKD FLNLCDLVVQ GDLQIAIRRL KPLLDAPSWK LKSHSAKRTS KQKSSEQTKI 360
361 TSSTKITKAI GLNTKSNDSS KKDNTSFQLH QVLNSIEIPK VEIKQEVEYA TPSPL
|
| Detection Method: |  |
| Confidence: | 64.221849 |
| Match: | 1q14A |
| Description: | Structure and autoregulation of the yeast Hst2 homolog of Sir2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein deacetylase activity | 9.15022242957651 | bayes_pls_golite062009 |
| histone deacetylase activity | 9.04876491350231 | bayes_pls_golite062009 |
| NAD-dependent protein deacetylase activity | 8.13038616303736 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity | 8.13038616303736 | bayes_pls_golite062009 |
| deacetylase activity | 8.11496387956068 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K14 specific) | 6.02509672218091 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 5.83127897351395 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity (H3-K9 specific) | 4.76068488405318 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity (H3-K14 specific) | 4.76068488405318 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity (H4-K16 specific) | 4.51070381823692 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K9 specific) | 3.4896257195243 | bayes_pls_golite062009 |
| transcription regulator activity | 2.9155913558118 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 2.82468859281133 | bayes_pls_golite062009 |
| DNA binding | 2.43141001866996 | bayes_pls_golite062009 |
| nucleic acid binding | 2.41433477472968 | bayes_pls_golite062009 |
| transcription repressor activity | 2.24657784428979 | bayes_pls_golite062009 |
| binding | 2.06552694538163 | bayes_pls_golite062009 |
| histone binding | 1.71445510915336 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.64212790017753 | bayes_pls_golite062009 |
| nucleosome binding | 1.5125174755597 | bayes_pls_golite062009 |
| transcription factor activity | 1.30143289828088 | bayes_pls_golite062009 |
| transcription factor binding | 1.14766678956419 | bayes_pls_golite062009 |
| tubulin deacetylase activity | 1.11434618720209 | bayes_pls_golite062009 |
| NAD or NADH binding | 0.877271524804045 | bayes_pls_golite062009 |
| catalytic activity | 0.739210399081789 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.54005617175343 | bayes_pls_golite062009 |
| transferase activity | 0.483523935618287 | bayes_pls_golite062009 |
| protein binding | 0.475479132768057 | bayes_pls_golite062009 |
| NAD+ ADP-ribosyltransferase activity | 0.0099486881187274 | bayes_pls_golite062009 |
