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View Structure Prediction Details

Protein: SPBC887.18c
Organism: Schizosaccharomyces pombe
Length: 339 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC887.18c.

Description E-value Query
Range
Subject
Range
gi|1145779 - gi|1145779|gb|AAA84983.1| Hfi1p
336.0 [0..11] [326..50]
gi|28922500, gi|... - gi|32406094|ref|XP_323660.1| predicted protein [Neurospora crassa], gi|28922500|gb|EAA31730.1| hypot...
gi|85100450 - gi|85100450|ref|XP_960966.1| hypothetical protein NCU04320 [Neurospora crassa OR74A]
310.0 [0..2] [268..25]
gi|28950180 - gi|28950180|emb|CAD71048.1| related to transcriptional coactivator HFI1 [Neurospora crassa]
306.0 [0..2] [268..25]
gi|38110449, gi|... - gi|39952343|ref|XP_363888.1| hypothetical protein MGG_01814 [Magnaporthe grisea 70-15], gb|EAA56163....
304.0 [0..1] [258..23]
gi|46136787, gi|... - gi|46136787|ref|XP_390085.1| hypothetical protein FG09909.1 [Gibberella zeae PH-1], gi|42547292|gb|E...
293.0 [0..8] [264..33]
gi|67900922, gi|... - gi|67900922|ref|XP_680717.1| hypothetical protein AN7448.2 [Aspergillus nidulans FGSC A4], ref|XP_41...
286.0 [0..7] [257..1575]
gi|45198350, gi|... - gi|45198350|ref|NP_985379.1| AFL171Wp [Ashbya gossypii ATCC 10895], gi|44984237|gb|AAS53203.1| AFL17...
gi|44984237 - gi|44984237|gb|AAS53203.1| AFL171Wp [Ashbya gossypii ATCC 10895]
280.0 [0..17] [281..48]
orf19.307, orf19... - orf19.307 CGDID:CAL0004632 Assembly 19, Contig19-10046 (133186, 131714) CDS, reverse complemented, t...
gi|68471918, gi|... - gi|68471918|ref|XP_720002.1| hypothetical protein CaO19.307 [Candida albicans SC5314], gi|68471655|r...
279.0 [0..12] [280..43]
gi|169769486 - gi|169769486|ref|XP_001819213.1| hypothetical protein [Aspergillus oryzae RIB40]
gi|83767071 - gi|83767071|dbj|BAE57211.1| unnamed protein product [Aspergillus oryzae]
256.0 [0..15] [257..37]

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Predicted Domain #1
Region A:
Residues: [1-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEGVTVQKV QSASSNGHKP NTVISQIISE MQSLLGSSFE VYTKTMTDFL IGQLSRKEMK  60
   61 SMLLTFAGKS NFDKLHNSII FHILKLMQKN NDTFSALHHL PWFKRKKVDN SLFLHKKISS 120
  121 QNAQVRLIKR IVMS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [135-191]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSYKDRARIK TALKEKPVTP SLISGLLLET RIAKLPKIPV SRDKLNSVFV NDIKAGY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [192-339]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VAPLACETLE LPDSESLKER ITAISLENGL LGGVQKGVSD IILAGLESHL KNILSRCFSI  60
   61 LNKNIRQKNT ENDAAGFTIN DLNLAWTIEP HAFVEQYPQK LRMPFLLHDS YTEDEISICA 120
  121 ESPSYMLASN DAQSDRNSVA SLLDEVLS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.976
Match: 1h3oA
Description: TAF(II)-135, (TAF(II)-130, hTAF4), histone fold domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
histone acetyltransferase activity 5.93249134612505 bayes_pls_golite062009
lysine N-acetyltransferase activity 5.93249134612505 bayes_pls_golite062009
N-acetyltransferase activity 4.49084162254966 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 4.4864586197085 bayes_pls_golite062009
N-acyltransferase activity 4.2172829451557 bayes_pls_golite062009
DNA binding 4.00167809338753 bayes_pls_golite062009
transcription regulator activity 3.91807454227165 bayes_pls_golite062009
acetyltransferase activity 3.91533222675137 bayes_pls_golite062009
nucleic acid binding 3.72299085850948 bayes_pls_golite062009
binding 3.67149228723241 bayes_pls_golite062009
acyltransferase activity 3.38996237245502 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.35419529667223 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.18312128320637 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.02428691626433 bayes_pls_golite062009
transcription factor activity 2.18855864512878 bayes_pls_golite062009
transcription initiation factor activity 1.61443429710414 bayes_pls_golite062009
protein binding 1.22636497573761 bayes_pls_golite062009
transcription activator activity 1.12739348005764 bayes_pls_golite062009
transcription factor binding 1.01773884290535 bayes_pls_golite062009
transcription coactivator activity 0.976797801726735 bayes_pls_golite062009
transcription cofactor activity 0.840442755533537 bayes_pls_golite062009
transcription repressor activity 0.621482805601238 bayes_pls_golite062009
histone binding 0.184823910505751 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.126825123711624 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle