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View Structure Prediction Details

Protein: SPBC19F5.02c
Organism: Schizosaccharomyces pombe
Length: 710 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC19F5.02c.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
620.0 [0..6] [666..1165]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
605.0 [0..14] [710..865]
gi|148658115, gi... - gi|148658115|ref|YP_001278320.1| NB-ARC domain-containing protein [Roseiflexus sp. RS-1], gi|1485702...
603.0 [0..3] [709..811]
gi|75701503, gi|... - gi|75907778|ref|YP_322074.1| ribosome assembly protein 4 (RSA4) [Anabaena variabilis ATCC 29413], gi...
586.0 [0..50] [700..1028]
gi|110168368, gi... - gi|71673858|ref|ZP_00671606.1| G-protein beta WD-40 repeat [Trichodesmium erythraeum IMS101], gi|716...
585.0 [0..6] [703..838]

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Predicted Domain #1
Region A:
Residues: [1-615]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIHRCRFID YTPSAITAMA FSHKSGQNDS MPNNLLLAVG RASGNIEIWN PRNDWCLKTV  60
   61 LYGGVDRSIE GIVWSTGEEE LRLFSIGFST TITEWNLHTG KPLVNQDSNA GAIWSIAICD 120
  121 ETKTLAVGCD DGSCVLFDIS GGPGVIEFKR VLMRQTSRIL SLDFQTKDHL VGGCADGVIK 180
  181 VWDLSTPNSA IISRMQVDRA RKGEAALIWA VKSLRDGTIV SADSSGAVKF WNGKFFTLSQ 240
  241 SFKLHLADAL CLGVSANGDM VFSSGIDRKT IQYSREGGKR EWVSNSFRRF HSHDVRCMAV 300
  301 FECKSLDVLI SGGMDMMLAV IPVRQFNRKN HRMISAVPQR PRMAVAPKAR LFMLWNDHEV 360
  361 LLWRIGSPGY RFLLKIVLAD EENISHAAIS PDGELIAISS VLRTKLYQLQ YSDENVKVET 420
  421 VEDSFLSNIG ASLLSFTVDK NKLILVSNDS EIFLIELSRL DSRQLEVFEL SQPTSKKIAP 480
  481 RQRSNVSSMC DGICSIAVSS DGDYFAVADT VGNIFCYSLS NLTYSELPRV NTYVRAMAFR 540
  541 PDVRGRLAVA TAGNQVYEFD VQSRKLSEWS KNNSTNMPKE FSQLLDKAFG AFFDSKHPSR 600
  601 FWIWSANWVS FFDLN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.221849
Match: 1nr0A
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
snoRNA binding 6.03079504484743 bayes_pls_golite062009
3.41022148055944 bayes_pls_golite062009
RNA binding 3.0829625416797 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
transcription regulator activity 2.3610959773142 bayes_pls_golite062009
nucleic acid binding 2.30918780727915 bayes_pls_golite062009
protein binding 2.26925404328312 bayes_pls_golite062009
DNA binding 1.71685536470455 bayes_pls_golite062009
cytoskeletal protein binding 1.5283366007575 bayes_pls_golite062009
structural molecule activity 1.31060431370834 bayes_pls_golite062009
transcription activator activity 1.23969853550045 bayes_pls_golite062009
transcription factor activity 1.08768505897883 bayes_pls_golite062009
actin binding 0.794986868016276 bayes_pls_golite062009
transcription repressor activity 0.658573452658359 bayes_pls_golite062009
transcription factor binding 0.489473003915035 bayes_pls_golite062009
transcription cofactor activity 0.30761651528651 bayes_pls_golite062009
ligase activity 0.280267687917718 bayes_pls_golite062009
tubulin binding 0.194781260474147 bayes_pls_golite062009
transcription corepressor activity 0.182612389752591 bayes_pls_golite062009
microtubule binding 0.167936232702449 bayes_pls_golite062009
mRNA binding 0.0519838181830878 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [616-710]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQLPAPRAAG KRKIEMNATV DGNLNDKKLA NANSNGISNY GTGDSRCFWI THKYRPMLLV  60
   61 GSVGNSELLV VERPIADMLM SKSMPASFYE HKFGS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.39794
Match: 1k32A
Description: Tricorn protease; Tricorn protease N-terminal domain; Tricorn protease domain 2
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle