YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC977.14c
Organism:	Schizosaccharomyces pombe
Length:	351 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC977.14c.

Description	E-value	Query Range	Subject Range
gi\|33596263 - gi\|33596263\|ref\|NP_883906.1\| putative oxidoreductase [Bordetella parapertussis 12822] gi\|33573266 - gi\|33573266\|emb\|CAE36928.1\| putative oxidoreductase [Bordetella parapertussis]	323.0	[0..7]	[349..1]
gi\|33602077, gi\|... - gi\|33602077\|ref\|NP_889637.1\| putative oxidoreductase [Bordetella bronchiseptica RB50], gi\|33576515\|e...	323.0	[0..7]	[349..1]
gi\|42546330, gi\|... - gi\|46109854\|ref\|XP_381985.1\| hypothetical protein FG01809.1 [Gibberella zeae PH-1], gi\|42546330\|gb\|E...	322.0	[0..4]	[351..1]
gi\|33592063, gi\|... - gi\|33592063\|ref\|NP_879707.1\| putative oxidoreductase [Bordetella pertussis Tohama I], gi\|33571707\|em...	321.0	[0..7]	[349..1]
gi\|115433338, gi... - gi\|115433338\|ref\|XP_001216806.1\| hypothetical protein ATEG_08185 [Aspergillus terreus NIH2624], gi\|1...	319.0	[0..5]	[349..578]
gi\|78062171, gi\|... - gi\|78062171\|ref\|YP_372079.1\| aldo/keto reductase [Burkholderia sp. 383], gi\|77970056\|gb\|ABB11435.1\| ...	316.0	[0..7]	[349..1]
gi\|50119681, gi\|... - gi\|50119681\|ref\|YP_048848.1\| putative aldo/keto reductase [Pectobacterium atrosepticum SCRI1043], gi...	313.0	[0..7]	[350..1]
gi\|68227685, gi\|... - gi\|68227685\|ref\|ZP_00566891.1\| Aldo/keto reductase [Frankia sp. EAN1pec], gi\|68204973\|gb\|EAN19139.1\|...	313.0	[0..5]	[349..71]
gi\|63255741, gi\|... - gi\|66045034\|ref\|YP_234875.1\| aldo/keto reductase [Pseudomonas syringae pv. syringae B728a], gi\|63255...	311.0	[0..7]	[349..1]
gi\|71737520, gi\|... - gi\|71737520\|ref\|YP_273981.1\| aldo/keto reductase family oxidoreductase [Pseudomonas syringae pv. pha...	311.0	[0..7]	[349..1]

Back

Predicted Domain #1

Region A:
Residues: [1-351]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLSPELYG CLGNSGLKVS KLILGCMSYG KKEYWEDWVL EDEEEVFKIM KAAYDAGIRT  60
   61 FDTANCYSAG VSEELVGKFI RKYEIPRSSI VILSKCFFPV RKDLIKIFGD LSSRGVHFLD 120
  121 SPELANQCGL SRKHIFDAVE DSVKRLGTYI DVLQIHRYDP HVSAEEVMRA LNDVVESGKV 180
  181 RYIGASTMRC YQFIELQNTA EKHGWHKFIS MQNYHNLLYR EEEREMIPYC QKTGVGLIPW 240
  241 SPLARGLLTR SIDANEETIR SKTDLYTRAL EFGAGYKAIL SRVEELAKKY NVSMATLATA 300
  301 WSLHKGDYPI VGISKVERLK DALAAVELKL SEEDIKYLEE PYCPVPIQGE I

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	71.522879
Match:	1pyfA
Description:	Structure of NADPH-dependent family 11 aldo-keto reductase AKR11A(apo)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
potassium channel activity	7.51963276589303	bayes_pls_golite062009
voltage-gated potassium channel activity	7.40239094355354	bayes_pls_golite062009
voltage-gated cation channel activity	6.67507110634301	bayes_pls_golite062009
metal ion transmembrane transporter activity	6.588881463055	bayes_pls_golite062009
voltage-gated ion channel activity	6.52286930358188	bayes_pls_golite062009
voltage-gated channel activity	6.50716590143831	bayes_pls_golite062009
cation channel activity	5.72172645555113	bayes_pls_golite062009
ion channel activity	5.15119282480682	bayes_pls_golite062009
passive transmembrane transporter activity	5.07214658557001	bayes_pls_golite062009
channel activity	5.07214658557001	bayes_pls_golite062009
substrate-specific channel activity	5.02503292701043	bayes_pls_golite062009
gated channel activity	4.92848832197692	bayes_pls_golite062009
aldo-keto reductase activity	3.79117514230146	bayes_pls_golite062009
ion transmembrane transporter activity	2.63772951680109	bayes_pls_golite062009
cation transmembrane transporter activity	2.58068601897668	bayes_pls_golite062009
aryl-alcohol dehydrogenase activity	2.5168190536972	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.46488926936937	bayes_pls_golite062009
aldehyde reductase activity	2.19831490122079	bayes_pls_golite062009
catalytic activity	1.68179794468736	bayes_pls_golite062009
transporter activity	1.24767072239634	bayes_pls_golite062009
binding	1.15657176144267	bayes_pls_golite062009
transmembrane transporter activity	1.03420335553507	bayes_pls_golite062009
potassium channel regulator activity	1.03017249802223	bayes_pls_golite062009
substrate-specific transporter activity	0.783004917746429	bayes_pls_golite062009
oxidoreductase activity	0.409822872480823	bayes_pls_golite062009
protein binding	0.220529867719707	bayes_pls_golite062009
3-alpha-hydroxysteroid dehydrogenase (B-specific) activity	0.207008954325429	bayes_pls_golite062009
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	0.207008954325429	bayes_pls_golite062009
	0.139676323362391	bayes_pls_golite062009
channel regulator activity	0.12154513851913	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.0465377885825481	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.0143508436041874	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: