| Protein: | fhl1 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 743 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fhl1.
| Description | E-value | Query Range |
Subject Range |
|
|
222.0 | [0..2] | [391..46] |
|
|
178.0 | [0..16] | [658..7] |
|
|
163.0 | [0..3] | [641..73] |
|
|
159.0 | [0..3] | [737..26] |
|
|
157.0 | [0..21] | [647..36] |
|
|
155.0 | [0..20] | [535..61] |
|
|
155.0 | [0..98] | [743..851] |
|
|
154.0 | [0..21] | [647..177] |
|
|
152.0 | [0..9] | [150..2] |
|
Region A: Residues: [1-155] |
1 11 21 31 41 51
| | | | | |
1 MPVAEIKNAT QQPSSTNRVQ AYAKLEFEKF SFFVQTLQVT MGRKASNSSD CDVHLGDTKA 60
61 ISRQHAKIFY SFPNQRFEIS VMGKNGAFVD GEFVERGKSV PLRSGTRVQI GQISFSFLLP 120
121 EGSEEDGHLK ETGITPLSLQ QGKIAYSDEF GGKPT
|
| Detection Method: |  |
| Confidence: | 13.39794 |
| Match: | 1lgqA |
| Description: | Cell cycle checkpoint protein Chfr |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 3.6561903894619 | bayes_pls_golite062009 |
| transcription regulator activity | 3.49687772656017 | bayes_pls_golite062009 |
| protein binding | 3.44553762357492 | bayes_pls_golite062009 |
| DNA binding | 3.30334070294767 | bayes_pls_golite062009 |
| nucleic acid binding | 3.21526555447097 | bayes_pls_golite062009 |
| transforming growth factor beta receptor, cytoplasmic mediator activity | 3.11955149440894 | bayes_pls_golite062009 |
| transcription activator activity | 2.94935902482394 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase signaling protein activity | 2.89799244272809 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.88406197124131 | bayes_pls_golite062009 |
| transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity | 2.71069110696713 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.61166537801555 | bayes_pls_golite062009 |
| R-SMAD binding | 2.6025306793153 | bayes_pls_golite062009 |
| promoter binding | 2.30493918456602 | bayes_pls_golite062009 |
| transcription factor activity | 2.08449567315174 | bayes_pls_golite062009 |
| co-SMAD binding | 1.88371912855333 | bayes_pls_golite062009 |
| transcription repressor activity | 1.74929788315626 | bayes_pls_golite062009 |
| SMAD binding | 1.58868248655216 | bayes_pls_golite062009 |
| chromatin binding | 1.44267609273288 | bayes_pls_golite062009 |
| transcription factor binding | 0.95553719139833 | bayes_pls_golite062009 |
| receptor signaling protein activity | 0.578078880190858 | bayes_pls_golite062009 |
| protein dimerization activity | 0.33340925100096 | bayes_pls_golite062009 |
| histone binding | 0.27452633104793 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.242323296067 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.163947452198109 | bayes_pls_golite062009 |
| transforming growth factor beta receptor binding | 0.161373857796846 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase binding | 0.161373857796846 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 0.15013949452504 | bayes_pls_golite062009 |
| receptor binding | 0.0581553668794451 | bayes_pls_golite062009 |
| identical protein binding | 0.0513801649373811 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.0339057097360133 | bayes_pls_golite062009 |
|
Region A: Residues: [156-276] |
1 11 21 31 41 51
| | | | | |
1 GSFHTVTSNQ EKDLLFSHIK HESDLPLGLS PADTNISNAT SIIEHPDAAN AHTLASLNQP 60
61 PKHLTVSPSS IQRLSPQPYV RPTSDERPIE TDSSVSAPKV ANHDEELKQG KSTSPSDTVL 120
121 H
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [277-383] |
1 11 21 31 41 51
| | | | | |
1 PDLNGSPDTG DATQKPNLSY ANLIARTLIA NPNKKMTLGD ICEWIANNWS YYRHQPPAWH 60
61 NSIRHNLSLN KAFIRIPRRQ NEPGKGSFWM LDPSYIDQFE GNFFRRT
|
| Detection Method: | |
| Confidence: | 31.045757 |
| Match: | 1d5vA |
| Description: | Adipocyte-transcription factor FREAC-11 (s12, fkh-14) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.55329976718261 | bayes_pls_golite062009 |
| DNA binding | 5.08959163553491 | bayes_pls_golite062009 |
| nucleic acid binding | 4.99681957904233 | bayes_pls_golite062009 |
| transcription factor activity | 4.33152142980289 | bayes_pls_golite062009 |
| transcription repressor activity | 3.85678231380989 | bayes_pls_golite062009 |
| transcription activator activity | 3.70589483230587 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.58179858678904 | bayes_pls_golite062009 |
| binding | 3.52874320222492 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.60738445921725 | bayes_pls_golite062009 |
| protein binding | 1.80415286835431 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.2723726467408 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 0.96257232341735 | bayes_pls_golite062009 |
| transcription factor binding | 0.85714789329232 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.66743181561551 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.322180400748724 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.23177057841536 | bayes_pls_golite062009 |
|
Region A: Residues: [384-482] |
1 11 21 31 41 51
| | | | | |
1 KKPTPSATPA AHPDTARENE LAAIQTKGIS AGKTEQLNPQ KETSRSKTHT SRGENVEDRP 60
61 QSLLQNGIQP IIMRDGKLAL NPEFFKNANG EQQAPNEQA
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [483-587] |
1 11 21 31 41 51
| | | | | |
1 VQAISLLQQH INKQLGPAAA NNPEQATAIA NALAVALAQK LQKQQTQMQG PQQVQQQAKR 60
61 RKAYTSQQLN PAPTAMPHPN ITSPSPSISV TQRPAVNVGP PPYVR
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [588-743] |
1 11 21 31 41 51
| | | | | |
1 PSAPSKLPDT RQSIGDPLPP GAMANVSAGP SSVRSSSYNS TASESKSEIT SHQNLHTIPI 60
61 NKPFTSDRPL YSSPNDTLER VETGNQGQRM NSIGNASSFS KRDIMENENG SFDTNAKNGN 120
121 NVDDSSSVRG MNLPSNSSDA LRGVKRPLDE TSSSYT
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
