YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC12B10.05
Organism:	Schizosaccharomyces pombe
Length:	486 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC12B10.05.

Description	E-value	Query Range	Subject Range
gi\|109481041, gi... - gi\|194474100\|ref\|NP_001124054.1\| X-prolyl aminopeptidase (aminopeptidase P) 3, putative [Rattus norv...	376.0	[0..1]	[485..1]
gi\|48146909 - gi\|48146909\|emb\|CAG33677.1\| LOC63929 [Homo sapiens]	372.0	[0..1]	[485..1]
gi\|114686551 - gi\|114686551\|ref\|XP_515152.2\| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes]	372.0	[0..1]	[485..1]
XPP3_PONAB - Probable Xaa-Pro aminopeptidase 3 OS=Pongo abelii GN=XPNPEP3 PE=2 SV=1 XPP3_PONPY - Putative Xaa-Pro aminopeptidase 3 - Pongo pygmaeus (Orangutan)	371.0	[0..1]	[485..1]
gi\|67972222 - gi\|67972222\|dbj\|BAE02453.1\| unnamed protein product [Macaca fascicularis]	360.0	[0..19]	[485..2]
gi\|73969474 - gi\|73969474\|ref\|XP_538358.2\| PREDICTED: similar to CG9581-PA [Canis familiaris]	355.0	[0..1]	[485..1]
gi\|49088114, gi\|... - gi\|67522647\|ref\|XP_659384.1\| hypothetical protein AN1780.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	352.0	[0..2]	[485..18]
gi\|76617043 - gi\|76617043\|ref\|XP_585578.2\| PREDICTED: hypothetical protein [Bos taurus]	350.0	[0..18]	[485..23]

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Predicted Domain #1

Region A:
Residues: [1-486]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGYIRTLFI RNRFSNYRLR SQIIKYKYSN VSYLNKSALR CGQATDSTHP HILQPGELTP  60
   61 RISAQEYKTR RDRVASLLED NDFMIVTSAP VRHMCGAAFY EYHQDPNFYY LTGCLEPNAV 120
  121 LLMFKNGASG SYDCSLYLPS KNPYIEKWEG LRTGSTLGKK LFQIENVYDS SLASSVINAL 180
  181 GKKSNRIFYN YQTGYLSKMP AASAPEFIQD TLTKLFRTST QRSVDELLHP LRSIKSTAEL 240
  241 ECMKEAANIS SNVYREIMRK RFEKEAEMSA EFNYRFCIGG CDRSAYVPVV AGGKNGLTIH 300
  301 YTINNDIFRP DEMVLVDAGG EFGGYVTDIS RTWPINGKFS TVQRDLYQAV LNVQKKCIKY 360
  361 CCTSNGWSLA DIHFESVKLM HEELKQVGIH GTKREITDIL YPHSIGHEIG LEIHDCSTNN 420
  421 GYQPLRKNQV ITIEPGLYVP EEDGWPQWAQ GIAIRIEDSV IVGDDKPFVL TSAAPKEIEE 480
  481 IEALKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	94.221849
Match:	1jawA
Description:	AMINOPEPTIDASE P FROM E. COLI LOW PH FORM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidase activity	2.60615909541559	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	2.18503136472662	bayes_pls_golite062009
metallopeptidase activity	1.75829852010848	bayes_pls_golite062009
hydrolase activity	1.43646476372001	bayes_pls_golite062009
aminopeptidase activity	0.89399203910285	bayes_pls_golite062009
binding	0.762408229471586	bayes_pls_golite062009
exopeptidase activity	0.762255574851485	bayes_pls_golite062009
nucleic acid binding	0.352607952828331	bayes_pls_golite062009
catalytic activity	0.148551873544128	bayes_pls_golite062009
transcription regulator activity	0.0346092896934742	bayes_pls_golite062009
DNA binding	0.0315289262145955	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: