Protein: | brc1 |
Organism: | Schizosaccharomyces pombe |
Length: | 878 amino acids |
Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for brc1.
Description | E-value | Query Range |
Subject Range |
|
354.0 | [0..15] | [869..7] |
|
344.0 | [0..19] | [874..5] |
|
343.0 | [0..11] | [868..1] |
|
338.0 | [0..13] | [874..6] |
|
317.0 | [0..16] | [868..8] |
|
312.0 | [0..17] | [868..9] |
|
303.0 | [0..13] | [873..5] |
|
290.0 | [0..14] | [873..3] |
|
273.0 | [0..18] | [871..1] |
|
268.0 | [0..7] | [860..599] |
Region A: Residues: [1-86] |
1 11 21 31 41 51 | | | | | | 1 MEKIKLLNVK TPNHYTIIFK VVAYYSALQP NQNELRKKEL FIKNDGKALS FPYDWKLATH 60 61 VICDDFSSPN VQEGSKRSLR LAKTNW |
Detection Method: | |
Confidence: | 21.39794 |
Match: | 1wf6A |
Description: | The third BRCA1 C-terminus (BRCT) domain of Similar to S.pombe rad4+/cut5+ product |
Matching Structure (courtesy of the PDB): |
Term | Confidence | Notes |
damaged DNA binding | 2.78264840479873 | bayes_pls_golite062009 |
DNA binding | 2.7698198756738 | bayes_pls_golite062009 |
nucleic acid binding | 2.61633684028078 | bayes_pls_golite062009 |
transcription regulator activity | 2.5081824552293 | bayes_pls_golite062009 |
binding | 2.39904249850929 | bayes_pls_golite062009 |
sequence-specific DNA binding | 1.41538783957147 | bayes_pls_golite062009 |
telomeric DNA binding | 1.26128385496855 | bayes_pls_golite062009 |
protein binding | 1.25126059595954 | bayes_pls_golite062009 |
transcription activator activity | 0.855915697559548 | bayes_pls_golite062009 |
transcription factor binding | 0.79968459369401 | bayes_pls_golite062009 |
structure-specific DNA binding | 0.436014478237905 | bayes_pls_golite062009 |
catalytic activity | 0.17721113579921 | bayes_pls_golite062009 |
double-stranded DNA binding | 0.163902958036495 | bayes_pls_golite062009 |
transcription repressor activity | 0.00883892441550604 | bayes_pls_golite062009 |
Region A: Residues: [87-387] |
1 11 21 31 41 51 | | | | | | 1 IRDCVDKNTL LNYSFYSCNP YLLFKGICAS SCQIDSYQSS LIDDALETFG GRFSKGLMKS 60 61 MTHLFTYSGM GAKCKKVLDK PSLSIKLIHP QWLLDCLQFG QLIDQDPYLF PNPSYKKNDS 120 121 SISKAEPTSL FRNVLHGKRI YFSNDLNLPT NFRHSLQKFS VGIGAKIAES INDCDIFIGL 180 181 KRDTIEFNLA SNKNTTIGTI SWLLNLFVLG SWKSPLLNAL HYPFPSVGFL KDQMVAVTNY 240 241 TDAARIYLEK LLLACGATYT KDLKPTNTLL IAASSYGQKY GAAKVWNIPT VHHSWLYSSF 300 301 K |
Detection Method: | |
Confidence: | 35.39794 |
Match: | 2owoA |
Description: | No description for 2owoA was found. |
Region A: Residues: [388-458] |
1 11 21 31 41 51 | | | | | | 1 NLSSQAFTDF PVPLDDSYMD FIFPCPLNVE KGSFEDTLKS SLTKGNSEVL LDDLSDPSVS 60 61 SIKGNKTNEE L |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
Region A: Residues: [459-650] |
1 11 21 31 41 51 | | | | | | 1 EKEFKSTSDN FGKHIILTSS FSNQSADKGS SLAAEDDRND EGSTITGVNR ELQDEGRLEI 60 61 DAKSSKTNTP PSPLLVGTPS KESLKEASSD DELPVLATKL VDNVIKEKSP LSLTPKVVVP 120 121 SHKETYTDEK KLIDELDRVN PLNSSQLLRS KRKSAATALS MLQNVIMPDV LAFEREKKRR 180 181 QTHRSVSSGE VS |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
Region A: Residues: [651-878] |
1 11 21 31 41 51 | | | | | | 1 RESSESRNTN AKASKRVYIT FTGYDKKPSI DNLKKLDMSI TSNPSKCTHL IAPRILRTSK 60 61 FLCSIPYGPC VVTMDWINSC LKTHEIVDEE PYLLNDPEKE LELGCTLESA LKRARAQGPS 120 121 LLEDYVVYLT SKTVAPENVP AVISIVKSNG GVCSTLNVYN KRLARHLEDG NVVLITCNED 180 181 SHIWTNFLDN ASQNKTIFLQ NYDWLIKTVL RQEIDVNDRI ADEFARAV |
Detection Method: | |
Confidence: | 41.0 |
Match: | 2azmA |
Description: | Crystal structure of the MDC1 brct repeat in complex with the histone tail of gamma-H2AX |
Matching Structure (courtesy of the PDB): |