| Protein: | Tf2-11 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 1333 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Tf2-11.
| Description | E-value | Query Range |
Subject Range |
|
|
1428.0 | [0..4] | [1326..71] |
|
|
1427.0 | [0..4] | [1326..327] |
|
Region A: Residues: [1-180] |
1 11 21 31 41 51
| | | | | |
1 MSYANYRYMK ARAKRWRPEN LDGIQTSDEH LINLFAKILS KHVPEIGKFD PNKDVESYIS 60
61 KLDQHFTEYP SLFPNEHTKR QYTLNHLEEL EQQFAERMFS ENGSLTWQEL LRQPGKVQGS 120
121 NKGDRLTKTF EGFRNQLDKV QFIRKLMSKA NVDDFHTRLF ILWMLPYSLR KLKERNYWKS 180
181
|
| Detection Method: |  |
| Confidence: | 21.045757 |
| Match: | 1e6jP |
| Description: | HIV capsid protein, dimerisation domain; HIV-1 capsid protein |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 1.28448955239851 | bayes_pls_golite062009 |
| transcription regulator activity | 0.786413651497179 | bayes_pls_golite062009 |
| nucleic acid binding | 0.548058390008807 | bayes_pls_golite062009 |
| DNA binding | 0.541861348095563 | bayes_pls_golite062009 |
|
Region A: Residues: [181-238] |
1 11 21 31 41 51
| | | | | |
1 EISEIYDFLE DKRTASYGKT HKRFQPQNKN LGKEFLPKKN NTTNSRNLRK TNISRIEY
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [239-393] |
1 11 21 31 41 51
| | | | | |
1 SSNKFLNHTR KRYEMVLQAE LPDFKCSIPC LIDTGTQANI ITEETVRAHK LPTRPWSKSV 60
61 IYGGVYPNKI NRKTIKLNIS LNGISIKTEF LVVKKFSHPA AISFTTLYDN NIEISSSKHT 120
121 LSQMNKVSNI VKEPELPDIY KEFKDITAET NTEKL
|
| Detection Method: | |
| Confidence: | 24.154902 |
| Match: | 1hvcA |
| Description: | CRYSTAL STRUCTURE OF A TETHERED DIMER OF HIV-1 PROTEASE COMPLEXED WITH AN INHIBITOR |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| hydrolase activity | 0.934096653248474 | bayes_pls_golite062009 |
| catalytic activity | 0.778715931979077 | bayes_pls_golite062009 |
| endopeptidase activity | 0.478344177019014 | bayes_pls_golite062009 |
| peptidase activity | 0.476168407632189 | bayes_pls_golite062009 |
| aspartic-type endopeptidase activity | 0.403642706513097 | bayes_pls_golite062009 |
| aspartic-type peptidase activity | 0.403642706513097 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 0.229854266530628 | bayes_pls_golite062009 |
| binding | 0.151374799700247 | bayes_pls_golite062009 |
|
Region A: Residues: [394-920] |
1 11 21 31 41 51
| | | | | |
1 PKPIKGLEFE VELTQENYRL PIRNYPLPPG KMQAMNDEIN QGLKSGIIRE SKAINACPVM 60
61 FVPKKEGTLR MVVDYKPLNK YVKPNIYPLP LIEQLLAKIQ GSTIFTKLDL KSAYHLIRVR 120
121 KGDEHKLAFR CPRGVFEYLV MPYGISIAPA HFQYFINTIL GEVKESHVVC YMDNILIHSK 180
181 SESEHVKHVK DVLQKLKNAN LIINQAKCEF HQSQVKFIGY HISEKGFTPC QENIDKVLQW 240
241 KQPKNRKELR QFLGSVNYLR KFIPKTSQLT HPLNNLLKKD VRWKWTPTQT QAIENIKQCL 300
301 VSPPVLRHFD FSKKILLETD ASDVAVGAVL SQKHDDDKYY PVGYYSAKMS KAQLNYSVSD 360
361 KEMLAIIKSL KHWRHYLEST IEPFKILTDH RNLIGRITNE SEPENKRLAR WQLFLQDFNF 420
421 EINYRPGSAN HIADALSRIV DETEPIPKDS EDNSINFVNQ ISITDDFKNQ VVTEYTNDTK 480
481 LLNLLNNEDK RVEENIQLKD GLLINSKDQI LLPNDTQLTR TIIKKYH
|
| Detection Method: | |
| Confidence: | 165.0 |
| Match: | 1lw0A |
| Description: | HIV RNase H (Domain of reverse transcriptase); HIV-1 reverse transcriptase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nucleotidyltransferase activity | 1.11992657762408 | bayes_pls_golite062009 |
| DNA polymerase activity | 0.97735803396704 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 0.966025256970563 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.870949824174184 | bayes_pls_golite062009 |
| binding | 0.452590422306309 | bayes_pls_golite062009 |
| catalytic activity | 0.282562363863898 | bayes_pls_golite062009 |
| transferase activity | 0.280309374132814 | bayes_pls_golite062009 |
| ribonuclease activity | 0.164715045017202 | bayes_pls_golite062009 |
|
Region A: Residues: [921-1220] |
1 11 21 31 41 51
| | | | | |
1 EEGKLIHPGI ELLTNIILRR FTWKGIRKQI QEYVQNCHTC QINKSRNHKP YGPLQPIPPS 60
61 ERPWESLSMD FITALPESSG YNALFVVVDR FSKMAILVPC TKSITAEQTA RMFDQRVIAY 120
121 FGNPKEIIAD NDHIFTSQTW KDFAHKYNFV MKFSLPYRPQ TDGQTERTNQ TVEKLLRCVC 180
181 STHPNTWVDH ISLVQQSYNN AIHSATQMTP FEIVHRYSPA LSPLELPSFS DKTDENSQET 240
241 IQVFQTVKEH LNTNNIKMKK YFDMKIQEIE EFQPGDLVMV KRTKTGFLHK SNKLAPSFAG 300
301
|
| Detection Method: | |
| Confidence: | 71.0 |
| Match: | 1k6yA |
| Description: | N-terminal Zn binding domain of HIV integrase; Retroviral integrase, catalytic domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1221-1333] |
1 11 21 31 41 51
| | | | | |
1 PFYVLQKSGP NNYELDLPDS IKHMFSSTFH VSHLEKYRHN SELNYATIDE SDIGTILHIL 60
61 EHKNREQVLY LNVKYISNLN PSTIMSGWTT LATALQADKA IVNDYIKNNN LNI
|
| Detection Method: | |
| Confidence: | 1.31 |
| Match: | 1pdqA |
| Description: | Polycomb chromodomain complexed with the histone H3 tail containing trimethyllysine 27. |
Matching Structure (courtesy of the PDB): |
|
